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New explortion of 61-82-5

Category: Triazoles. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Fandzloch, M; Augustyniak, AW; Dobrzanska, L; Jedrzejewski, T; Sitkowski, J; Wypij, M; Golinska, P or concate me.

Fandzloch, M; Augustyniak, AW; Dobrzanska, L; Jedrzejewski, T; Sitkowski, J; Wypij, M; Golinska, P in [Fandzloch, Marzena] PAS, Inst Low Temp & Struct Res, Okolna 2, PL-50422 Wroclaw, Poland; [Augustyniak, Adam W.] Univ Wroclaw, Fac Chem, F Joliot Curie 14, PL-50383 Wroclaw, Poland; [Dobrzanska, Liliana] Nicolaus Copernicus Univ Torun, Fac Chem, Gagarina 7, PL-87100 Torun, Poland; [Jedrzejewski, Tomasz] Nicolaus Copernicus Univ Torun, Fac Biol & Vet Sci, Dept Immunol, Lwowska 1, PL-87100 Torun, Poland; [Sitkowski, Jerzy] Natl Inst Med, Chelmska 30-34, PL-00725 Warsaw, Poland; [Sitkowski, Jerzy] Polish Acad Sci, Inst Organ Chem, Kasprzaka 44-52, PL-01224 Warsaw, Poland; [Wypij, Magdalena; Golinska, Patrycja] Nicolaus Copernicus Univ Torun, Fac Biol & Vet Sci, Dept Microbiol, Lwowska 1, PL-87100 Torun, Poland published First dinuclear rhodium(II) complexes with triazolopyrimidines and the of their use in 2020.0, Cited 82.0. Category: Triazoles. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Five novel rhodium(II) complexes of general formula [Rh-2(mu-OOCCH3)(4)L-2], where L is a triazolopyrimidine derivative, in particular dimethyl-1,2,4-triazolo[1,5-a]pyrimidine (dmtp) for (1), 5,7-diethyl-1,2,4-triazolo[1,5a]pyrimidine (detp) for (2), 7-isobutyl-5-methyl-1,2,4-triazolo[1,5-a]pyrimidine (ibmtp) for (3), 7-hydroxy-5methyl-1,2,4-triazolo[1,5-a]pyrimidine (HmtpO) for (4) and 5,7-ditertbutyl-1,2,4-triazolo[1,5-a]pyrimidine (dbtp) for (5) are reported. These first representatives of paddle-wheel dirhodium complexes with triazolopyrimidines have been characterized by IR and NMR spectroscopy as well as by single-crystal X-ray diffraction studies. Three of the new complexes (1), (2) and (5) were thoroughly screened in vitro for their cytotoxicity against human breast cancer cell line MCF-7 and L929 murine fibroblast cells. Favorably, they show significantly less effective inhibition on the cell growth of L929 than cisplatin under identical conditions. Complexes (1) and (5) display moderate cytotoxic activity (IC50 = 16.3-21.5 mu M) against MCF-7 cells which is induced via reactive oxygen species-independent pathways. Extensive studies of rhodium complexes (1), (2) and (5) against microorganisms have shown that the tested compounds exhibit antibacterial activity against Gram-positive bacteria (Staphylococcus aureus and Bacillus subtilis) while (5) significantly inhibited the growth of Malassezia furfur. The highest antibacterial, and antifungal activity, was observed for (5).

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Extracurricular laboratory: Synthetic route of 1H-1,2,4-Triazol-5-amine

Computed Properties of C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Umar, T; Shalini, S; Raza, MK; Gusain, S; Kumar, J; Seth, P; Tiwari, M; Hoda, N or concate me.

Umar, T; Shalini, S; Raza, MK; Gusain, S; Kumar, J; Seth, P; Tiwari, M; Hoda, N in [Umar, Tarana; Hoda, Nasimul] Jamia Millia Islamia, Dept Chem, New Delhi 110025, India; [Shalini, Shruti; Gusain, Siddharth; Seth, Prerna; Tiwari, Manisha] Univ Delhi, Dr BR Ambedkar Ctr Biomed Res, New Delhi 110007, India; [Raza, Md Kausar] Indian Inst Sci, Dept Inorgan & Phys Chem, Bangalore 560012, Karnataka, India; [Kumar, Jitendra] Sardar Vallabhbhai Patel Coll, Dept Chem, Bhabua 821101, Kaimur, India; [Kumar, Jitendra] VKSU, Ara 802301, Bihar, India published A multifunctional therapeutic approach: Synthesis, biological evaluation, crystal structure and molecular docking of diversified 1H-pyrazolo[3,4-b]pyridine derivatives against Alzheimer’s disease in 2019.0, Cited 65.0. Computed Properties of C2H4N4. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

2-(piperazin-1-yl)-N-(1H-pyrazolo[3,4-b]pyridin-3-yl)acetamides are described as a new class of selective and potent acetylcholinesterase (AChE) inhibitors and amyloid beta aggregation inhibitors. Formation of synthesized compounds (P1-P9) was justified via H-1 NMR, C-13 NMR, mass spectra and single crystal X-Ray diffraction study. All compounds were evaluated for their acetylcholinesterase and butyrylcholinesterase inhibitory activity, inhibition of self-mediated A beta aggregation and Cu(II)-mediated A beta aggregation. Also, docking study carried out was in concordance with in vitro results. The most potent molecule amongst the derivatives exhibited excellent anti-AChE activity (IC50=4.8 nM). Kinetic study of P3 suggested it to be a mixed type inhibitor. In vitro study revealed that all the compounds are capable of inhibiting self-induced beta-amyloid (A beta) aggregation with the highest inhibition percentage to be 81.65%. Potency of P1 and P3 to inhibit self-induced A beta(1-)(42) aggregation was ascertained by TEM analysis. Compounds were also evaluated for their A beta disaggregation, antioxidation, metal-chelation activity. (C) 2019 Elsevier Masson SAS. All rights reserved.

Machine Learning in Chemistry about 61-82-5

About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Chen, S; Wang, YT; An, ZH; Ma, M; Shi, YQ; Wang, X or concate me.. Category: Triazoles

I found the field of Thermodynamics; Chemistry very interesting. Saw the article Stability, antibacterial ability, and inhibition of zinc burning of amitrole as thermal stabilizer for transparent poly(vinyl chloride) published in 2019.0. Category: Triazoles, Reprint Addresses Wang, X (corresponding author), Zhejiang Univ Technol, Coll Mat Sci & Engn, Hangzhou 310014, Zhejiang, Peoples R China.. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

Amitrole is reported as a novel kind of transparent poly(vinyl chloride) (PVC) thermal stabilizer that has both excellent inhibition of zinc burning thermal stability and antibacterial ability in this paper, which provide the possibility of applying the whole PVC industry into medical and food packaging, artificial leather, wire and cable, indoor decoration, and so on. From the results of Congo red test, discoloration test, and dynamic thermal stability test, we could clearly find out that amitrole could effectively replace the unstable chlorine atom and inhibit zinc burning of transparent PVC, while the long-term stability should be improved. Next, the stabilization mechanism of amitrole was also confirmed. The antibacterial activity of amitrole was measured by the bacteriostatic ring experiments. It was observed that the PVC films had good antibacterial properties after modified by amitrole. At last, optimal design of the amitrole/ZnSt(2) (1:1)/ESBO formulation was studied, which have strong potential as thermal stabilizer to prepare super transparency and antibacterial PVC resin.

About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Chen, S; Wang, YT; An, ZH; Ma, M; Shi, YQ; Wang, X or concate me.. Category: Triazoles

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Recommanded Product: 1H-1,2,4-Triazol-5-amine. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Li, B; Kuang, Y; Yi, Y; Qiao, X; Liang, L; Ye, M or concate me.

I found the field of Pharmacology & Pharmacy; Chemistry very interesting. Saw the article Chemical modifications of ergostane-type triterpenoids from Antrodia camphorata and their cytotoxic activities published in 2021.0. Recommanded Product: 1H-1,2,4-Triazol-5-amine, Reprint Addresses Liang, L; Ye, M (corresponding author), Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, 38 Xueyuan Rd, Beijing 100191, Peoples R China.. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

In order to discover potential antitumor agents from natural products, chemical modifications of ergostane-type triterpenoids from Antrodia camphorata yielded ten new compounds. They include nine C-26 amide derivatives of antcin G (1) and a methyl antcin B (4) derivative with hydroxyamino groups at C-3 and C-7. Chemical structures of the new compounds were elucidated by NMR and MS analyses. Furthermore, cytotoxicities of the triterpenoid derivatives were evaluated using four human cancer cell lines (HL60, U251, SW480, and MCF-7). As a result, 1a, 1g, and 4a exhibited potent cytotoxic activities against HL60, U251, and SW480 with IC50 values of 0.7 +/- 0.9, 2.9 +/- 1.3, and 2.2 +/- 0.6 mu M, respectively. Molecular docking indicates that 1a, 1g, and 4a have strong binding affinity with DNA topoisomerase II alpha (-9.3, -7.9, and -7.4 kcal/mol, respectively), and that they could be potent topoisomerase II alpha inhibitors.

Recommanded Product: 1H-1,2,4-Triazol-5-amine. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Li, B; Kuang, Y; Yi, Y; Qiao, X; Liang, L; Ye, M or concate me.

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HPLC of Formula: C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Liu, X; Zhan, J; Jing, XY; Zhou, SG; Lovley, DR or concate me.

HPLC of Formula: C2H4N4. In 2019.0 ENVIRON MICROBIOL published article about INTERSPECIES ELECTRON-TRANSFER; IV PILI; PROTEIN; REDUCTION; NANOWIRES; EXCHANGE; FE(III) in [Liu, Xing; Zhan, Ji; Jing, Xianyue; Zhou, Shungui] Fujian Agr & Forestry Univ, Coll Resources & Environm, Fujian Prov Key Lab Soil Environm Hlth & Regulat, Fuzhou, Fujian, Peoples R China; [Lovley, Derek R.] Univ Massachusetts, Dept Microbiol, Amherst, MA 01003 USA in 2019.0, Cited 44.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Mechanisms controlling the expression of the electrically conductive pili (e-pili) of Geobacter species are of interest because of the important role of e-pili in diverse biogeochemical processes, anaerobic digestion and electromicrobiological applications. We investigated the function of the protein, designated Spc (short pilin chaperone), encoded by the gene immediately downstream from the gene for PilA, the monomer that assembles into e-pili. Multiple lines of evidence suggest that Spc forms an oligomer that is associated with the inner membrane. Mutating the start codon of spc to prevent translation increased the transcript abundance of pilA but greatly diminished the abundance of PilA, and e-pili could no longer be detected. Cross-linking, protein capture and two-hybrid studies demonstrated that Spc and PilA interacted. Two sites in PilA for electrostatic interaction with Spc were identified. The results demonstrate that Spc is required for PilA stability prior to incorporation into e-pili, suggesting that Spc has a chaperone function that may be specific to the relatively short PilA monomers that assemble into e-pili. These results are important for identifying microorganisms likely to express e-pili from (meta)genomic data and for the construction of microbial strains expressing e-pili.

HPLC of Formula: C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Liu, X; Zhan, J; Jing, XY; Zhou, SG; Lovley, DR or concate me.

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About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Lahmidi, S; Anouar, EH; El Hafi, M; Boulhaoua, M; Ejjoummany, A; El Jemli, M; Essassi, EM; Mague, JT or concate me.. Recommanded Product: 1H-1,2,4-Triazol-5-amine

Recommanded Product: 1H-1,2,4-Triazol-5-amine. Recently I am researching about PHENOLIC SCHIFF-BASES; NMR CHEMICAL-SHIFTS; TRIAZOLOPYRIMIDINE; MECHANISM; APPROXIMATION; INHIBITORS; COMPLEXES; HERBICIDE; POTENT; SAR, Saw an article supported by the . Published in ELSEVIER SCIENCE BV in AMSTERDAM ,Authors: Lahmidi, S; Anouar, EH; El Hafi, M; Boulhaoua, M; Ejjoummany, A; El Jemli, M; Essassi, EM; Mague, JT. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

Two new (4-5) and a known (3) derivatives of 1,2,4-triazolo [1,5-a]pyrimidine are synthesized and characterized through spectroscopic NMR, FT-IR and single crystal X-ray diffraction techniques. Along with experimental data, the predicted spectral data are obtained using density functional theory (DFT) at the B3LYP/6-31 + G (d,p) level of theory. The closest contacts between active atoms of the compounds are identified through Hirshfeld surface analysis and electrostatic potential map (EPM) studies. Relatively, good correlations were found between the experimental and predicted spectroscopic data with correlation coefficients higher than 90%. Hirshfeld surface analysis and EPM reveal that the closest interaction between the units of the compounds are between hydrogen atoms (39.6-46.3%). The antioxidant activity of 3-5 is evaluated using DPPH free radical scavenging and ferric reducing antioxidant power assays. (C) 2018 Elsevier B.V. All rights reserved.

How did you first get involved in researching 1H-1,2,4-Triazol-5-amine

About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Wu, J; Wu, WJ; Liang, JH; Jin, YJ; Gazzarrini, S; He, JN; Yi, MF or concate me.. Application In Synthesis of 1H-1,2,4-Triazol-5-amine

Application In Synthesis of 1H-1,2,4-Triazol-5-amine. In 2019.0 PLANT CELL PHYSIOL published article about ABSCISIC-ACID; SEED-GERMINATION; CELL-DIVISION; GENE-EXPRESSION; POTATO-TUBERS; CLASS-I; ARABIDOPSIS; CYTOKININ; GROWTH; BIOSYNTHESIS in [Wu, Jian; Wu, Wenjing; Liang, Jiahui; Jin, Yujie; He, Junna; Yi, Mingfang] China Agr Univ, Dept Ornamental Hort & Landscape Architecture, Beijing Key Lab Dev & Qual Control Ornamental Cro, Beijing 100193, Peoples R China; [Wu, Jian; Gazzarrini, Sonia] Univ Toronto Scarborough, Dept Biol Sci, Toronto, ON, Canada; [Gazzarrini, Sonia] Univ Toronto, Dept Cell & Syst Biol, Toronto, ON, Canada in 2019.0, Cited 55.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Dormancy is one of the least understood phenomena in plant biology; however, bud/corm dormancy is an important economic trait in agricultural/horticultural breeding. In this study, we isolated an ABA biosynthesis gene, GhNCED, from the transcriptome database of corm dormancy release (CDR), and characterized its negative role in regulating CDR. To understand transcriptional regulation of GhNCED, yeast one-hybrid screening was conducted and GhTCP19 was identified and shown to regulate GhNCED expression directly. An in planta assay showed that GhTCP19 negatively regulates GhNCED expression. GhTCP19 is dramatically induced by exogenous cytokinins (CKs) and is induced during CDR. Silencing of GhTCP19 in dormant cormels delayed CDR, resulting in higher expression of GhNCED and ABA levels. Meanwhile, endogenous CK biosynthesis and signaling were inhibited in GhTCP19-silenced cormels. Taken together, our results reveal that GhTCP19 is a positive regulator of the CDR process by repressing expression of an ABA biosynthesis gene (GhNCED), promoting CK biosynthesis (GhIPT) and signal transduction (GhARR) as well as inducing cyclin genes. This study expands our knowledge on CDR which is mediated by TCP family members.

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Computed Properties of C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Chen, Y; Chen, YH; Zhang, YJ; Zhang, DP; Li, GM; Wei, JL; Hua, X; Lv, B; Liu, LJ or concate me.

Computed Properties of C2H4N4. Authors Chen, Y; Chen, YH; Zhang, YJ; Zhang, DP; Li, GM; Wei, JL; Hua, X; Lv, B; Liu, LJ in TAYLOR & FRANCIS INC published article about in [Chen, Yun; Liu, Lijun] Yangzhou Univ, Jiangsu Key Lab Crop Genet & Physiol, Jiangsu Coinnovat Ctr Modern Prod Technol Grain C, Jiangsu Key Lab Crop Genom & Mol Breeding, Yangzhou, Jiangsu, Peoples R China; [Chen, Yun; Chen, Yuanhua; Zhang, Yajun; Zhang, Dongping; Li, Guoming; Wei, Jiali; Hua, Xia; Lv, Bing] Yangzhou Univ, Coll Biosci & Biotechnol, Yangzhou, Jiangsu, Peoples R China in 2021.0, Cited 49.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

Heterotrimeric G-protein a and beta-subunits regulate H2O2-mediated aerenchyma formation. The rice G-protein gamma-subunit, dense and erect panicle 1 (DEP1), is known to interact with the a-subunit and regulate nitrogen utilization and yield. However, it is unclear whether DEP1 regulates cell death for aerenchyma formation in rice roots. Using wild-type WYJ8 and its transgenic line WYJ8(DEPJ), we confirmed that DEP1 is involved in H2O2-mediated aerenchyma formation. The rates of aerenchyma formation varied in different parts of the roots in both varieties, with the highest rate in the 4-7 cm segments, reaching a plateau in the 7-8 cm segments. Compared with WYJ8, the aerenchyma area and H2O2 content in WYJ8(DEP1) were increased by 55.98% and 53.37%, respectively; however, the responses of aerenchyma formation to exogenous H2O2 were basically the same in the two varieties. Diphenylene iodonium (DPI) treatment had no effect on H2O2 production and elimination processes in WYJ8, but significantly reduced the activity of the key enzyme that catalyzes H2O2 biosynthesis in WYJ8(DEP1). Importantly, exogenous H2O2 treatment did not offset the effect of the decrease in endogenous H2O2 level caused by DPI on aerenchyma formation. These results indicated that DEP1 enhanced H2O2 biosynthesis and promoted the cell death of the root cortex, thus contributing to aerenchyma development in WYJ8(DEP1).

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SDS of cas: 61-82-5. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Allemang, A; De Abrew, KN; Shan, YQK; Krailler, JM; Pfuhler, S or concate me.

In 2021.0 ENVIRON MOL MUTAGEN published article about NONGENOTOXIC CHEMICALS; RECOMMENDED LISTS; OXIDATIVE STRESS; FOLLOW-UP; ASSAY; PERFORMANCE; MUTAGENESIS; QUERCETIN; THRESHOLD; TESTS in [Allemang, Ashley; De Abrew, K. Nadira; Shan, Yuqing K.; Pfuhler, Stefan] Procter & Gamble Co, Global Prod Stewardship, Cincinnati, OH USA; [Krailler, Jesse M.] Procter & Gamble Co, Data & Modeling Sci, Cincinnati, OH USA in 2021.0, Cited 35.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. SDS of cas: 61-82-5

A key step in the risk assessment process of a substance is the assessment of its genotoxic potential. Irrespective of the industry involved, current approaches rely on combinations of two or three in vitro tests and while highly sensitive, their specificity is thought to be limited. A refined in vitro genotoxicity testing strategy with improved predictive capacity would be beneficial and 3R friendly as it helps to avoid unnecessary in vivo follow-up testing. Here, we describe a proof of concept study evaluating a balanced set of compounds that have in vivo negative or positive outcomes, but variable in vitro data, to determine if we could differentiate between direct and indirect acting genotoxicants. Compounds were examined in TK6 cells using an approach in which the same sample was used to evaluate both early genomic markers (Affymetrix analysis 4 hr post treatment), and the genotoxic outcome (micronuclei [MN] after 24 hr). The resulting genomic data was then analyzed using the TGx-DDI biomarker, Connectivity mapping and whole genome clustering. Chemicals were also tested in the ToxTracker assay, which uses six different biomarker genes. None of the methods correctly differentiated all direct from indirect acting genotoxicants when used alone, however, the ToxTracker assay, TGx-DDI biomarker and whole genome approaches provided high predictive capacity when used in combination with the MN assay (1/18, 2/18, 1/18 missed calls). Ultimately, a fit for purpose combination will depend on the specific tools available to the end user, as well as considerations of the unique benefits of the individual assays.

SDS of cas: 61-82-5. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Allemang, A; De Abrew, KN; Shan, YQK; Krailler, JM; Pfuhler, S or concate me.

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Computed Properties of C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Dawood, DH; Nossier, ES; Ali, MM; Mahmoud, AE or concate me.

In 2020.0 BIOORG CHEM published article about GROWTH-FACTOR RECEPTOR-2; BIOLOGICAL EVALUATION; ANTICANCER EVALUATION; INHIBITORS; ANGIOGENESIS; RESISTANCE; MECHANISM; DISCOVERY; DESIGN in [Dawood, Dina H.] Natl Res Ctr, Chem Nat & Microbial Prod Dept, Pharmaceut & Drug Ind Res Div, 33 El Bohouth St,POB 12622, Giza, Egypt; [Nossier, Eman S.] Al Azhar Univ, Fac Pharm Girls, Dept Pharmaceut Chem, POB 11754, Cairo, Egypt; [Ali, Mamdouh M.; Mahmoud, Abeer E.] Natl Res Ctr, Biochem Dept, Genet Engn & Biotechnol Res Div, 33 El Bohouth St,POB 12622, Giza, Egypt in 2020.0, Cited 50.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. Computed Properties of C2H4N4

Based on the previous studies that revealed the valuable role of pyrazole scaffold in cancer management and VEGFR-2 inhibition, a new set of pyrazole conjugated with pyrazoline, triazolopyrimidine and pyrazolone moieties were synthesized and investigated for their anticancer efficiency against human breast cancer MCF-7. The anticancer screening revealed the significant sensitivity of breast carcinoma towards compounds 4b, 5c, 6c, 7b, 7c and 12c with IC50 values ranging from 16.50 – 26.73 mu M in comparison with tamoxifen (IC50 = 23.31 mu M). Moreover, the new analogues were further examined for their VEGFR-2 inhibitory activity, among the tested derivatives 5c, 6c, 7b, 7c and 12c displayed prominent inhibitory efficiency versus VEGFR-2 kinase with % inhibition ranging from 70 to 79%. Compounds 6c, 7c and 12c revealed inhibitory efficiency in nanomolar level with IC50 (913.51, 225.17 and 828.23 nM, respectively) comparing to sorafenib (IC50 = 186.54 nM). Flow cytometric analysis revealed that the promising compound 12c prompted pre-G1 apoptosis and cell growth cessation at G2/M phase and stimulated apoptosis via activation of caspase-3. Moreover, molecular docking study of the promising derivatives was performed to highlight their binding modes and interactions with the amino acid residues of VEGFR-2 enzyme.

Computed Properties of C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Dawood, DH; Nossier, ES; Ali, MM; Mahmoud, AE or concate me.