Awesome and Easy Science Experiments about C2H4N4

Quality Control of 1H-1,2,4-Triazol-5-amine. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Kargarpour, Z; Nasirzade, J; Di Summa, F; Panahipour, L; Miron, RJ; Gruber, R or concate me.

Quality Control of 1H-1,2,4-Triazol-5-amine. Recently I am researching about HEAT INACTIVATION; CATALASE; ANTIOXIDANTS; RELEASE; OXIDANT, Saw an article supported by the Osteology Foundation, Switzerland [17-125, 17-219]; Austrian Science Fund (FWF)Austrian Science Fund (FWF) [4072-B28]. Published in MDPI in BASEL ,Authors: Kargarpour, Z; Nasirzade, J; Di Summa, F; Panahipour, L; Miron, RJ; Gruber, R. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

Hydrogen peroxide is a damage signal at sites of chronic inflammation. The question arises whether platelet-rich fibrin (PRF), platelet-poor plasma (PPP), and the buffy coat can neutralize hydrogen peroxide toxicity and thereby counteract local oxidative stress. In the present study, gingival fibroblasts cells were exposed to hydrogen peroxide with and without lysates obtained from PRF membranes, PPP, heated PPP (75 degrees C for 10 min), and the buffy coat. Cell viability was examined by trypan blue staining, live-dead staining, and formazan crystal formation. Cell apoptosis was assessed by cleaved caspase-3 Western blot analysis. Reverse transcription-quantitative polymerase chain reaction (RT-PCR) was utilized to determine the impact of PRF lysates on the expression of catalase in fibroblasts. It was reported that lysates from PRF, PPP, and the buffy coat-but not heated PPP-abolished the hydrogen peroxide-induced toxicity in gingival fibroblasts. Necrosis was confirmed by a loss of membrane integrity and apoptosis was ruled out by the lack of cleavage of caspase-3. Aminotriazole, an inhibitor of catalase, reduced the cytoprotective activity of PRF lysates yet blocking of glutathione peroxidase by mercaptosuccinate did not show the same effect. PRF lysates had no impact on the expression of catalase in gingival fibroblasts. These findings suggest that PRF, PPP, and the buffy coat can neutralize hydrogen peroxide through the release of heat-sensitive catalase.

Quality Control of 1H-1,2,4-Triazol-5-amine. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Kargarpour, Z; Nasirzade, J; Di Summa, F; Panahipour, L; Miron, RJ; Gruber, R or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Extended knowledge of 61-82-5

About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Polunin, KE; Ul’yanov, AV; Polunina, IA; Buryak, AK or concate me.. Safety of 1H-1,2,4-Triazol-5-amine

Safety of 1H-1,2,4-Triazol-5-amine. Authors Polunin, KE; Ul’yanov, AV; Polunina, IA; Buryak, AK in MAIK NAUKA/INTERPERIODICA/SPRINGER published article about in [Polunin, K. E.; Ul’yanov, A. V.; Polunina, I. A.; Buryak, A. K.] Russian Acad Sci, Frumkin Inst Phys Chem & Electrochem, Moscow 119071, Russia in 2021.0, Cited 21.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

The construction materials that contacted with unsymmetrical dimethylhydrazine and the desorption solutions obtained when treating the contaminated surface of metals and alloys with water and reagents were studied by chromatography and mass spectrometry. Neutralization of unsymmetrical dimethylhydrazine was studied using ozone and shungite. Ozonation makes it possible to destroy the toxicant molecules chemically and physically adsorbed on the surface of metal constructions, due to which they can be reused and utilized. Shungite effectively adsorbs and catalytically decomposes not only unsymmetrical dimethylhydrazine and its transformation products, but also oligomer compounds formed during the storage of hydrazine fuel. Ozonation of spent shungite can increase the efficiency of destructive processes and completeness of its regeneration.

About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Polunin, KE; Ul’yanov, AV; Polunina, IA; Buryak, AK or concate me.. Safety of 1H-1,2,4-Triazol-5-amine

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Extended knowledge of 61-82-5

About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Zhou, SH; Xu, HB; Liu, JY; Wei, YJ; Ma, XH; Han, ZM; Chen, HL or concate me.. Quality Control of 1H-1,2,4-Triazol-5-amine

An article Simplified synthesis of N-doped carbon nanotube arrayed mesoporous carbon for electrochemical detection of amitrole WOS:000609493900007 published article about GOLD NANOPARTICLES; NANOPOROUS CARBON; POROUS CARBON; SULFUR; SENSOR in [Zhou, Shenghai; Xu, Hongbo; Liu, Jinyu; Wei, Yajun; Ma, Xinhuan; Han, Zhimin; Chen, Hongli] Hebei Normal Univ Nationalities, Coll Chem & Chem Engn, Chengde 067000, Peoples R China in 2021.0, Cited 45.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. Quality Control of 1H-1,2,4-Triazol-5-amine

N-doped carbon nanopipe-arrayed mesoporous carbon (N-CMK-5) with double-pore system, large surface area (992 m(2)/g), and high nitrogen amount (5.2 at.%) was synthesized by a simplified template route. In this route, mesoporous silica was directly used instead of using time-consuming aluminosilicate as a template and the carbonization process occurred in a nitrogen atmosphere instead of a vacuum. Furthermore, CMK-3, N-doped CMK-3, and CMK-5 ordered mesopomus carbons (OMCs) were compared with the as-prepared N-doped CMK-5 (N-CMK-5) to investigate the effect of microstructure on the electrochemical activity of OMCs. N-CMK-5 exhibited higher electrochemical activity than the other OMCs because it has more exposed defective sites and nitrogen active species. The developed N-CMK-5-based electrochemical sensor showed good practical application for the electrochemical detection of pesticide amitrole in real water sample. This work contributes a simplified route to synthesize tubular N-CMK-5 carbon and provides valuable information on the design of high-performance carbon electrode materials.

About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Zhou, SH; Xu, HB; Liu, JY; Wei, YJ; Ma, XH; Han, ZM; Chen, HL or concate me.. Quality Control of 1H-1,2,4-Triazol-5-amine

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Our Top Choice Compound:61-82-5

Computed Properties of C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Zhu, TY; Yu, X; Yi, M; Wang, Y or concate me.

Recently I am researching about COMPOSITE MEMBRANES; WATER-ADSORPTION; HYBRID MEMBRANES; PDMS MEMBRANE; PERVAPORATION; RECOVERY; MIXTURES; ALCOHOL; SOLVENT; PERMEABILITY, Saw an article supported by the Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21878117]; Analysis and Testing Center; Analysis and Testing Center of Chemistry and Chemical Engineering School (HUST). Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Zhu, TY; Yu, X; Yi, M; Wang, Y. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine. Computed Properties of C2H4N4

The interfacial design is critical in preparing high-performance mixed matrix membranes (MMMs), especially for the separation of larger sized components from mixtures. Herein, a facile and novel strategy was employed to design covalently linked zeolitic imidazolate framework-8-polydimethylsiloxane (ZIF-8@PDMS) MMMs without interfacial defects by a onestep synthesis route for ethanol recovery from ethanol aqueous solution. In this strategy, 3-glycidyloxypropyltrimethoxysilane (GOPTS) worked as the covalent linker of PDMS and amine-functionalized ZIF-8 nanoparticles (AZIF-8) simultaneously. The chemical structures and morphologies of AZIF-8 and AZIF-8@PDMS MMMs were demonstrated by various characterization techniques. The results exhibited that AZIF-8 and the MMMs were successfully prepared and AZIF-8 as the filler displayed better dispersion in the PDMS matrix and compatibility with the PDMS matrix as compared to ZIF-8 or GOPTS-modified ZIF-8 (GZIF-8). Therefore, AZIF-8@PDMS MMMs showed more excellent separation performance than ZIF-8 or GZIF-8-filled MMMs. In particular, AZIF-8@PDMS MMM with 7 wt % AZIF-8 loading exhibited the highest separation factor of 17.7 and a comparable total flux of 585.6 g/m(2) h at 40 degrees C with 5 wt % ethanol aqueous solution, which were improved by 176.6 and 34.5%, respectively, in comparison with the pristine PDMS membrane, breaking the trade-off effect between the flux and separation factor. This study might provide some new insights into the fabrication of high-performance MMMs for pervaporation recovery of various organic systems.

Computed Properties of C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Zhu, TY; Yu, X; Yi, M; Wang, Y or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

The important role of C2H4N4

Quality Control of 1H-1,2,4-Triazol-5-amine. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Pandey, YK; Mishra, A; Rai, P; Singh, J; Singh, J; Singh, RK or concate me.

I found the field of Chemistry very interesting. Saw the article DBU Catalysis: An Efficient Synthetic Strategy for 5,7-disubstituted-1,2,4-triazolo[1,5-a]pyrimidines published in 2020.0. Quality Control of 1H-1,2,4-Triazol-5-amine, Reprint Addresses Singh, RK (corresponding author), Univ Allahabad, Dept Chem, Bioorgan Res Lab, Allahabad 211002, Uttar Pradesh, India.; Singh, J (corresponding author), Univ Allahabad, Dept Chem, Environm Benign Synth Lab, Allahabad 211002, Uttar Pradesh, India.. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

Aims and Objectives: An efficient and facile DBU catalysed synthesis of highly significant motif 5,7-disubstituted-1,2,4-triazolo[1,5-a]pyrimidines under solvent-free condition has been reported. Materials and Methods: To a round bottom flask, 1.0 mmol of chalcone (1), 1.5 mmol of 3-amino-1,2,4-triazole (2) and 30 mol% of DBU were added at 70 degrees C and stirred in solvent-free condition. After the completion of the reaction (monitored by TLC), water (10 ml) was added. The aqueous layer was extracted with ethyl acetate (3 x 10 ml). The combined organic layers were dried over anhydrous Na2SO4. The combined organic layers were evaporated under reduced pressure and the resulting crude product was purified by column chromatography by using ethyl acetate and hexane as eluent. Results: Reaction using chalcone and 3-amino-1,2,4-triazole as model substrates were carried out under different reaction conditions and it was observed that 30 mol% of DBU under the solvent-free condition at 70 degrees C was the optimum temperature for the proposed synthesis. Conclusion: Use of DBU (an organocatalyst) as a base, operational simplicity, high yield of products and short reaction time are some of the significant advantages associated with the proposed strategy.

Quality Control of 1H-1,2,4-Triazol-5-amine. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Pandey, YK; Mishra, A; Rai, P; Singh, J; Singh, J; Singh, RK or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

The Absolute Best Science Experiment for 61-82-5

About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Wen, D; Dong, Z; Ao, YY; Xie, KJ; Zhai, ML; Zhao, L or concate me.. Product Details of 61-82-5

Product Details of 61-82-5. Authors Wen, D; Dong, Z; Ao, YY; Xie, KJ; Zhai, ML; Zhao, L in ELSEVIER SCI LTD published article about in [Wen, Di; Dong, Zhen; Xie, Kangjun; Zhao, Long] Huazhong Univ Sci & Technol, Sch Elect & Elect Engn, State Key Lab Adv Electromagnet Engn & Technol, Wuhan 430074, Peoples R China; [Wen, Di; Xie, Kangjun] Huazhong Univ Sci & Technol, Sch Chem & Chem Engn, Wuhan 430074, Peoples R China; [Ao, Yinyong] China Acad Engn Phys, Inst Nucl Phys & Chem, Mianyang 621900, Sichuan, Peoples R China; [Zhai, Maolin] Peking Univ, Beijing Natl Lab Mol Sci Radiochem & Radiat Chem, Coll Chem & Mol Engn,Key Lab Fundamental Sci, Key Lab Polymer Chem & Phys,Minist Educ, Beijing 100871, Peoples R China in 2021.0, Cited 53.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

Aminotriazole isomers with high nitrogen content show potential affinity for U(VI). Combining the advantages of both aminotriazole and cellulose, two n-aminotriazole isomers modified cellulose microspheres (n-ATARs, n = 3, 4) were newly prepared as adsorbents via radiation technology. Batch adsorption experiments showed that n-ATARs possessed good adsorption capacity of U(VI) in the order of 3-ATAR > 4-ATAR, and the adsorption process followed the Langmuir-Freundlich isotherm model and the pseudo-second-order kinetic model. Both n-ATARs exhibited good selectivity and reusability. Besides, 3-ATAR and 4-ATAR were more suitable for the extraction of trace amount of U(VI) from the contaminated groundwater and the simulated seawater, respectively. The effect of amino position on triazole ring on adsorption behavior of n-ATAR was studied and explained by DFT calculation. Finally, the adsorption mechanism of U(VI) onto n-ATARs was revealed to be inner-sphere complexation via different 1:1 or 1:2 coordination models by FTIR, MS, XPS analysis and DFT calculation.

About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Wen, D; Dong, Z; Ao, YY; Xie, KJ; Zhai, ML; Zhao, L or concate me.. Product Details of 61-82-5

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Chemical Research in C2H4N4

Safety of 1H-1,2,4-Triazol-5-amine. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Jin, MM; Chen, Y; Song, WX; Lian, H; Guo, HE; Dong, QC; Huang, JH; Su, JH or concate me.

Safety of 1H-1,2,4-Triazol-5-amine. Jin, MM; Chen, Y; Song, WX; Lian, H; Guo, HE; Dong, QC; Huang, JH; Su, JH in [Jin, Minmin; Chen, Yi; Song, Wenxian; Su, Jianhua] East China Univ Sci & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China; [Jin, Minmin; Chen, Yi; Song, Wenxian; Su, Jianhua] East China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China; [Lian, Hong; Guo, Hongen; Dong, Qingchen] Taiyuan Univ Technol, MOE Key Lab Interface Sci & Engn Adv Mat, 79 Yingze West St, Taiyuan 030024, Shanxi, Peoples R China; [Lian, Hong; Guo, Hongen; Dong, Qingchen] Taiyuan Univ Technol, Res Ctr Adv Mat Sci & Technol, 79 Yingze West St, Taiyuan 030024, Shanxi, Peoples R China; [Huang, Jinhai] Shanghai Taoe Chem Technol Co Ltd, Shanghai, Peoples R China published Synthesis, characterization, and electroluminescent properties of indazole, pyrazole, and triazole/triphenylamine-based compounds in 2020.0, Cited 34.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

In this work, seven small molecular compounds named N,N-diphenyl-4-(2-phenylpyrimido [1,2-b]indazol-4-yl) aniline (1), N,N-diphenyl-4-(5-phenylpyrazolo [1,5-a]pyrimidin-7-yl)aniline (2), N,N-diphenyl-4-(5-phenyl[1,2,4]triazolo [1,5-a]pyrimidin-7-yl)aniline (3), 4,4′-(pyrimido [1,2-b]indazole-2,4-diyl)bis (N,N-diphenylaniline) (4), 4,4′-(pyrazolo [1,5-a]pyrimidine-5,7-diyl)bis (N,N-diphenylaniline) (5), 4,4′-([1,2,4]triazolo [1,5-a] pyrimidine-5,7-diyl)bis (N,N-diphenylaniline) (6), N,N-diphenyl-4-(4-phenylpyrimido [1,2-b]indazol-2-yl)aniline (7) with donor-acceptor (D-A) structure were designed and synthesized by employing triphenylamine (TPA) as donor and indazole, pyrazole and/or triazole as acceptor. Systematic study and analysis on thermal, photo physical, electrochemical properties of all compounds were performed. All compounds exhibit good thermal and morphological stabilities with decomposition temperatures (T-d) range from 270 to 462 degrees C, and glass transition temperatures (T-g) range from 78 to 127 degrees C. The investigation of photophysical properties of these compounds revealed that all these compounds are of high photoluminescence quantum yields (PLQY), particularly for compound 6, whose PLQY value was as high as 90.22%. To explore potential applications of these materials in organic light-emitting diodes (OLEDs), two devices with compounds 2 and 5 were fabricated. Both devices show excellent device performances with maximum current efficiency, maximum power efficiency and external quantum efficiency of 15.9 cd A(-1), 10.41 m W-1 and 8.4% for compound 2-based device and 10.1 cd A(-1), 5.81 m W-1 and 5.5% for compound 5-based device, respectively.

Safety of 1H-1,2,4-Triazol-5-amine. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Jin, MM; Chen, Y; Song, WX; Lian, H; Guo, HE; Dong, QC; Huang, JH; Su, JH or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

When did you first realize you had a special interest and talent inC2H4N4

About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Maza, S; Kijatkin, C; Bouhidel, Z; Pillet, S; Schaniel, D; Imlau, M; Guillot, B; Cherouana, A; Bendeif, EE or concate me.. Application In Synthesis of 1H-1,2,4-Triazol-5-amine

An article Synthesis, structural investigation and NLO properties of three 1,2,4-triazole Schiff bases WOS:000569381800021 published article about POROUS COORDINATION POLYMER; CRYSTAL-STRUCTURE; SPECTROSCOPIC CHARACTERIZATION; MOLECULAR-STRUCTURE; ANTIOXIDANT ACTIVITY; BIOLOGICAL-ACTIVITY; COMPLEXES; PATTERNS; DOCKING; STORAGE in [Maza, Soumeya; Bouhidel, Zakaria; Cherouana, Aoutef] Univ Freres Mentouri Constantine 1, Dept Chim, Unite Rech Chim Environm & Mol Struct CHEMS, Constantine 25000, Algeria; [Maza, Soumeya; Pillet, Sebastien; Schaniel, Dominik; Guillot, Benoit; Bendeif, El-Eulmi] Univ Lorraine, CRM2, CNRS, Nancy, France; [Kijatkin, Christian; Imlau, Mirco] Osnabruck Univ, Sch Phys, D-49076 Osnabruck, Germany; [Kijatkin, Christian; Imlau, Mirco] Osnabruck Univ, Res Ctr Cellular Nanoanalyt, CellNanOs, D-49076 Osnabruck, Germany in 2020.0, Cited 60.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. Application In Synthesis of 1H-1,2,4-Triazol-5-amine

We report in this work the synthesis, crystal structures analyses, and nonlinear-optical (NLO) properties of three Schiff bases with halogens and triazole moieties: (E)-1-(4-bromophenyl)-N-(1H-1,2,4-triazol-3yl)methanimine L1, (E)-1-(4-bromophenyl)-N-(4H-1,2,4-triazol-3-yl)methanimine L2, and (E)-1-(4chlorophenyl)-N-(4H-1,2,4-triazol-3-yl)methanimine L3. The three molecules are built on the basis of the same backbone formed by two aromatic rings (phenyl and triazole) linked by imine bridge. The two first compounds L1 and L2 contain tautomers of the Schiff base, where a phenyl ring is substituted by a bromine atom. The third one, L3, is similar to L2 but contains a chlorine atom instead of bromine. In crystals formed by these three Schiff bases the three dimensional networks are formed by supramolecular interactions such as hydrogen bonds, C-X…pi and X…X (X = Cl or Br) contacts. Complementary Hirshfeld surface analyses were carried out to investigate and quantify the contributions of the different intermolecular interactions within the supramolecular assemblies. These analyses reveal that the main contributions in the studied compounds are provided by the H center dot center dot center dot H and N center dot center dot center dot H interactions that represent-53% (for L1),-49% (for L2) and-50% (for L3) of the total contributions to the Hirshfeld surface. The nonlinear optical properties are investigated by nonlinear diffuse femtosecond-pulse reflectometry and are compared with those of the reference material LiNbO3, in particular regarding the temporal evolution. (C) 2020 Elsevier B.V. All rights reserved.

About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Maza, S; Kijatkin, C; Bouhidel, Z; Pillet, S; Schaniel, D; Imlau, M; Guillot, B; Cherouana, A; Bendeif, EE or concate me.. Application In Synthesis of 1H-1,2,4-Triazol-5-amine

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Why Are Children Getting Addicted To 61-82-5

Quality Control of 1H-1,2,4-Triazol-5-amine. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Seo, JE; Tryndyak, V; Wu, QG; Dreval, K; Pogribny, I; Bryant, M; Zhou, T; Robison, TW; Mei, N; Guo, XQ or concate me.

Recently I am researching about DOSE-RESPONSE RELATIONSHIPS; DNA-DAMAGE; MOUSE LYMPHOMA; MUTAGENICITY; PERFORMANCE; GAMMA-H2AX; EXPRESSION; INDUCTION; DEPARTURE; TOXICITY, Saw an article supported by the . Quality Control of 1H-1,2,4-Triazol-5-amine. Published in SPRINGER HEIDELBERG in HEIDELBERG ,Authors: Seo, JE; Tryndyak, V; Wu, QG; Dreval, K; Pogribny, I; Bryant, M; Zhou, T; Robison, TW; Mei, N; Guo, XQ. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

In vitro genotoxicity testing that employs metabolically active human cells may be better suited for evaluating human in vivo genotoxicity than current bacterial or non-metabolically active mammalian cell systems. In the current study, 28 compounds, known to have different genotoxicity and carcinogenicity modes of action (MoAs), were evaluated over a wide range of concentrations for the ability to induce DNA damage in human HepG2 and HepaRG cells. DNA damage dose-responses in both cell lines were quantified using a combination of high-throughput high-content (HTHC) CometChip technology and benchmark dose (BMD) quantitative approaches. Assays of metabolic activity indicated that differentiated HepaRG cells had much higher levels of cytochromes P450 activity than did HepG2 cells. DNA damage was observed for four and two out of five indirect-acting genotoxic carcinogens in HepaRG and HepG2 cells, respectively. Four out of seven direct-acting carcinogens were positive in both cell lines, with two of the three negatives being genotoxic mainly through aneugenicity. The four chemicals positive in both cell lines generated HTHC Comet data in HepaRG and HepG2 cells with comparable BMD values. All the non-genotoxic compounds, including six non-genotoxic carcinogens, were negative in HepaRG cells; five genotoxic non-carcinogens also were negative. Our results indicate that the HTHC CometChip assay detects a greater proportion of genotoxic carcinogens requiring metabolic activation (i.e., indirect carcinogens) when conducted with HepaRG cells than with HepG2 cells. In addition, BMD genotoxicity potency estimate is useful for quantitatively evaluating CometChip assay data in a scientifically rigorous manner.

Quality Control of 1H-1,2,4-Triazol-5-amine. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Seo, JE; Tryndyak, V; Wu, QG; Dreval, K; Pogribny, I; Bryant, M; Zhou, T; Robison, TW; Mei, N; Guo, XQ or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Our Top Choice Compound:1H-1,2,4-Triazol-5-amine

About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Al-Khodir, FAI; Al-Warhi, T; Abumelha, HMA; Al-Issa, SA or concate me.. Recommanded Product: 61-82-5

Recommanded Product: 61-82-5. In 2019.0 J MOL STRUCT published article about METAL-COMPLEXES; ANTICANCER; TRIAZINES; CU(II); CO(II); SERIES; COPPER; MODEL; DNA in [Al-Khodir, Fatima A. I.; Al-Warhi, Tarfah; Abumelha, Hana M. A.; Al-Issa, S. A.] Princess Nourah Bint Abdulrahman Univ, Coll Sci, Dept Chem, Riyadh, Saudi Arabia in 2019.0, Cited 61.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

A series of vital complexes of [Se (L-n) (Cl)(x)]center dot yCl (where n = L-1, L-2, L-3 and L-4; x = 1, 2, or 3 and y = 1, 2, or 3) and [Ru (L-n) (Cl)(x) (H2O)(y)]zCl (where x = 2 or 3; y = 0,1 or 2 and z = 0 or 1) have been synthesized from the chemical reactions between ruthenium (III) or selenium (IV) salts and tri-substituted s-triazine derivatives (L-1 = N-2-(4-chlorophenyl)-N-4,N-6-di (pyrimidin-2-yl)-1,3,5-triazine-2,4,6-triamine; L-2 = N-2-(4-chlorophenyl)-N-4- (pyrimidin-2-yl)- N-6-(thiazol-2-yl)-1,3,5-triazine-2,4,6-triamine; L-3 = 6-chloro-N-2-(pyrimidin-2-yl)-N-4-(1H-1,2,4-triazol-3-yl)-1,3,5-triazine-2,4-diamine and L-4 = 6-chloro-N-2-(4-chlorophenyl)-N-4-(pyrimidin-2-yl)-1,3,5-triazine-2,4-diamine). The structural was investigated using of elemental analyses, molar conductance, IR, UV-Vis, magnetic susceptibility, H-1, C-13 NMR spectra and thermal analyses. The surface morphology behaviors of selenium (IV) and ruthenium (111) complexes were studied based on scanning and transmittance electron microscopes. The crystalline nature of s-triazine complexes have been investigated using X-ray powder diffraction spectra. Spectral results were concluded that the ligand acts as a neutral bidentate for (L-1 and L-4) and tridentate for (L-2 and L-3), and coordinates through the nitrogen atom of triazine ring and nitrogen atoms of (pyrimidine, thiazole, and triazole) rings towards metal ion. The cytotoxic IC50 results of the free L-n ligands and its selenium (IV) complexes in vitro against the human colon and lung cancer cell lines introduced a promising efficiency. (C) 2018 Elsevier B.V. All rights reserved.

About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Al-Khodir, FAI; Al-Warhi, T; Abumelha, HMA; Al-Issa, SA or concate me.. Recommanded Product: 61-82-5

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics