Day: November 2, 2021

Formula: C2H4N4. In 2021.0 APPL ORGANOMET CHEM published article about METAL-COMPLEXES; CU(II) COMPLEXES; ANTIOXIDANT; NI(II); CO(II); HYDRAZIDE; SPECTRA; CD(II); MODELS; ZN(II) in [Majeed, Abdulnasir A.; Khalil, Mostafa M. H.; Abdel Aziz, Ayman A.] Ain Shams Univ, Dept Chem, Fac Sci, Cairo, Egypt; [Fetoh, Ahmed; Abu El-Reash, G. M.] Mansoura Univ, Dept Chem, Fac Sci, POB 70, Mansoura, Egypt in 2021.0, Cited 64.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

In this work, (Z)-N-benzoyl-N ‘-(1H-1,2,4-triazol-3-yl)carbamimidothioic acid and its Mn(II), Co(II), Cu(II) and Cd(II) complexes were introduced for the first time. This carbonyl thiourea ligand was prepared by the reaction of 1H-1,2,4-triazol-3-amine with benzoyl isothiocyanate. The structural elucidation of these compounds was performed using elemental analysis and spectral and magnetic measurements. Octahedral structures of all complexes, except Cd(II) complex with a tetrahedral geometry, were confirmed by applying DFT structural optimization. The thermal decomposition behaviour of metal complexes of carbonyl thiourea ligand is discussed. The calculation of kinetic parameters for prepared complexes (E-a, A, Delta H*, Delta S* and Delta G*) of all thermal degradation stages has been evaluated using two comparable approaches. Antimicrobial and ABTS-antioxidant studies indicated potent activity of Cd(II) complex compared with the other investigated compounds. The cytotoxic activity of the prepared compounds was investigated in vitro. The results indicated potent activity of Mn(II) complex against both HePG2 (liver carcinoma) and MCF-7 (breast carcinoma) cancer cells.

Formula: C2H4N4. Welcome to talk about 61-82-5, If you have any questions, you can contact Majeed, AA; Khalil, MMH; Fetoh, A; Aziz, AAA; Abu El-Reash, GM or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

I found the field of Biochemistry & Molecular Biology; Chemistry; Polymer Science very interesting. Saw the article Screening and analysis of agouti signaling protein interaction partners in Pelodiscus sinensis suggests a role in lipid metabolism published in 2020.0. Category: Triazoles, Reprint Addresses Si, YX (corresponding author), Zhejiang Chinese Med Univ, Sch Basic Med Sci, Hangzhou 310053, Peoples R China.; Qian, GY (corresponding author), Zhejiang Wanli Univ, Coll Biol & Environm Sci, Ningbo 315100, Peoples R China.. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

Agouti signaling protein (ASP) is a secreted paracrine protein that has been widely reported to function in melanogenesis and obesity and could potentially be a core protein that regulates the color and fatty phenotype of P. sinensis. In this study, we screened out interacting proteins of ASP by combined co-immunoprecipitation mass spectrometry (CoIP-MS), yeast two hybrid (Y2H) analysis, and computational predictions. We performed docking of ASP with its well-known receptor melanocortin receptor 4 (MC4R) to predict the binding capacity and to screen out actual ASP interacting proteins, CoIP-MS was performed where identified 32 proteins that could bind with ASP and Y2H confirmed seven proteins binding with ASP directly. CoIP-MS and Y2H screening results including PPI prediction revealed that vitronectin (VIN), apolipoprotein Al (AP0A1), apolipoprotein B (APOB), and filamin B (FLNB) were the key interacting proteins of ASP. VTN, AP0A1, and APOB are functional proteins in lipid metabolism and various skin disorders, suggesting ASP may function in lipid metabolism through these partners. This study provided protein-protein interaction information of ASP, and the results will promote further research into the diverse roles of ASP, as well as its binding partners, and their function in different strains of P. sinensis. (C) 2019 Published by Elsevier B.V.

Category: Triazoles. Welcome to talk about 61-82-5, If you have any questions, you can contact Zhang, LL; Yin, SJ; Zheng, XY; Chen, XW; Wang, Q; Park, YD; Qian, GY; Si, YX or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Zhao, YL; Lai, GD; Li, GG; Shang, YL; Shi, JC in [Zhao, Y. L.; Shi, J. C.] Peac Inst Multiscale Sci, Chengdu 610027, Sichuan, Peoples R China; [Lai, G. D.; Li, G. G.; Shang, Y. L.] Southwest Jiaotong Univ, Key Lab Adv Technol Mat, Minist Educ, Chengdu 610031, Sichuan, Peoples R China; [Lai, G. D.] Southwest Jiaotong Univ, Sch Phys Sci & Technol, Chengdu 610031, Peoples R China published Identifying C2H4N4 structural isomers using fs-laser induced breakdown spectroscopy in 2020.0, Cited 48.0. Product Details of 61-82-5. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Four C2H4N4 structural isomers are investigated with fs laser-induced breakdown spectroscopy. Plasma emissions, C I, H-alpha, the CN violet system (B-2 sigma(+)-X-2 sigma(+), Delta nu = 0 sequence) and C-2 swan system (d(3)pi(g)-a(3)pi(u), Delta nu = 0 sequence) are measured. The temporal evolution of the characteristic emission intensity is obtained for each emission and their lifetimes are calculated. The lifetimes of the molecular emissions are much longer than those of the atomic emissions. Characteristic emission intensities and lifetime are correlated with the molecular structures of the four isomers to a certain extent. Plasma temperature is extracted by fitting the spectrum of the CN violet system, B-2 sigma(+)-X-2 sigma(+); Delta nu = 0 sequence, and is weakly correlated with the molecular structures of the four isomers. Using the characteristic emission intensities as input, principal component analysis (PCA) and artificial neural network (ANN) analysis are performed and the individual isomers can be well identified with PCA or ANN.

Product Details of 61-82-5. Welcome to talk about 61-82-5, If you have any questions, you can contact Zhao, YL; Lai, GD; Li, GG; Shang, YL; Shi, JC or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

In 2019.0 J MOL STRUCT published article about METAL-ORGANIC FRAMEWORKS; IONIC LIQUID; INHIBITORS; DESIGN; DERIVATIVES; EFFICIENT; POTENT; WATER; ACID in [Abdollahi-Basir, Mohammad Hossein; Shirini, Farhad; Tajik, Hassan] Univ Guilan, Coll Sci, Dept Chem, Rasht 4133519141, Iran; [Ghasemzadeh, Mohammad Ali] Islamic Azad Univ, Qom Branch, Dept Chem, Qom, Iran in 2019.0, Cited 31.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. Quality Control of 1H-1,2,4-Triazol-5-amine

Zinc terephthalate metal-organic framework catalyzed one-pot, three-component reaction of 3-amino-1H-1,2,4-triazoles, aromatic aldehydes and barbituric acid to prepare some new pyrimido[4,5-d][1,2,4]triazolo[1,5-a]pyrimidinediones. The reactions conducted under ultrasonic irradiation and solvent-free conditions with good to excellent yields of products. The zinc terephthalate metal-organic framework catalyst could be recovered by a simple filtration and applied in consecutive runs with no significant decrease in the yield. The method was demonstrated to be a truly green process with economics and sustainability. (C) 2019 Elsevier B.V. All rights reserved.

Quality Control of 1H-1,2,4-Triazol-5-amine. Welcome to talk about 61-82-5, If you have any questions, you can contact Abdollahi-Basir, MH; Shirini, F; Tajik, H; Ghasemzadeh, MA or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Quality Control of 1H-1,2,4-Triazol-5-amine. Recently I am researching about INTRAMOLECULAR HYDROGEN-BOND; CRYSTAL-STRUCTURE; SOLID-STATE; SPECTROSCOPIC CHARACTERIZATION; DERIVATIVES; N-15; IR; H-1-NMR; 2-HYDROXY-1-NAPHTHALDEHYDE; UV/VIS, Saw an article supported by the National Science CentreNational Science Centre, Poland [2017/01/X/ST4/01132]. Published in ELSEVIER SCIENCE BV in AMSTERDAM ,Authors: Kolodziej, B; Morawiak, M; Schilf, W; Kamienski, B. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

In the present paper, twelve Schiff bases derived from 3-amino-1H-1,2,4-triazole (ATz) and various benzaldehydes, and salicylaldehydes were synthesized. The H-1, C-13, and N-15 NMR data are discussed in relation to the structure of ATz and its imine products. In addition, X-ray, ATR-FTIR, and UV-Vis analytical techniques are used for structure elucidation of ATz-based Schiff bases. It was found that the starting material, 3-amino-1H-1,2,4-triazole, exists as tautomeric mixture of three forms (Graphical Abstract) in solution, whereas in the solid state (C-13 and N-15 CPMAS data) potentially tautomeric proton is located on nitrogen atom traditionally marked as N-2 (Graphical Abstract, 2N-H structure). All investigated Schiff bases derived from salicylaldehydes exist in both phases as tautomeric equilibrium mixtures, where enol-imine forms are dominated structures. The positions of those equilibria only very slightly depend on substituents in phenol ring. Generally, the contributions of keto-amine forms in the solid state are higher comparing with DMSO solutions. (C) 2019 Published by Elsevier B.V.

Quality Control of 1H-1,2,4-Triazol-5-amine. Welcome to talk about 61-82-5, If you have any questions, you can contact Kolodziej, B; Morawiak, M; Schilf, W; Kamienski, B or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Recommanded Product: 1H-1,2,4-Triazol-5-amine. Zhang, Z; Zhang, L; He, L; Yuan, WL; Xu, DG; Tao, GH in [Zhang, Zhang; Zhang, Lei; He, Ling; Yuan, Wen-Li; Xu, Dingguo; Tao, Guo-Hong] Sichuan Univ, Coll Chem, Chengdu 610064, Sichuan, Peoples R China published Is it Always Chemical When Amino Groups Come Across CO2? Anion-Anion-Interaction-Induced Inhibition of Chemical Adsorption in 2019.0, Cited 46.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Amino-functionalized ionic liquids (IL) are often applied to fix CO2. However, as far as we know, none of them have ever been reported to exhibit considerable physical CO2 capture. Herein, we describe an amino-functionalized room-temperature ionic liquid, 1-butyl-3-methylimidazolium 3-amino-1H-1,2,4-triazolate ([Bmim][ATZ]), with an unusual ultrafast physical CO2 capture at room temperature and atmospheric pressure. Within the time needed for a chemisorbent to reach an equilibrium, 15 adsorption and desorption cycles are finished for [Bmim][ATZ], with an accumulative molar ratio of up to 2.04. The CO2/IL ratio for one adsorption process reaches 0.14, which is 4 times the highest recorded physical CO2 solubility by [thtdp][Cl] (trihexyltetradecylphosphonium chloride). The first theoretical study on anion-anion interactions of ionic liquids is reported, which rationalizes the inhibition of chemical adsorption. These results provide a new perspective on the aspect of CO2 capture, as well as designing of ionic liquids.

Recommanded Product: 1H-1,2,4-Triazol-5-amine. Welcome to talk about 61-82-5, If you have any questions, you can contact Zhang, Z; Zhang, L; He, L; Yuan, WL; Xu, DG; Tao, GH or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

I found the field of Biochemistry & Molecular Biology; Chemistry very interesting. Saw the article Synthesis, molecular docking and antimicrobial activity of new fused pyrimidine and pyridine derivatives published in 2020.0. Safety of 1H-1,2,4-Triazol-5-amine, Reprint Addresses Radwan, MAA; Alshubramy, MA (corresponding author), Qassim Univ, Dept Chem, Collage Sci, Buraydah, Saudi Arabia.. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

Synthesis of some new heterocyclic ring systems incorporated pyrimidine and pyridine moieties starting from 1-(furan-2-yl)-3-(thiophen-2-yl) chalcone was achieved. The structure of the new compounds was interpreted by spectral studies and ESI-MS analysis. Antimicrobial investigations of the designated compounds were performed towards some harmful pathogenic microbes. Antimicrobial tests proved that compound 11 unveiled a greater antimicrobial activity than other designed compounds. Docking of compound 11 into active site of DNA gyrase B chain displayed binding-energy of -13.05 kJ mol(-1) and distance at 3.18 A degrees. Furthermore, docking investigation was approved for the goal compounds into DNA gyrase B chain and exhibiting binding energy extended from -13.05 to -20.48 kJ mol(-1).

Safety of 1H-1,2,4-Triazol-5-amine. Welcome to talk about 61-82-5, If you have any questions, you can contact Radwan, MAA; Alshubramy, MA; Abdel-Motaal, M; Hemdan, BA; El-Kady, DS or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Safety of 1H-1,2,4-Triazol-5-amine. Li, MX; Lu, QJ; Liu, ML; Yin, P; Wu, CY; Li, HT; Zhang, YY; Yao, SZ in [Li, Mingxia; Lu, Qiujun; Liu, Meiling; Yin, Peng; Wu, Cuiyan; Li, Haitao; Zhang, Youyu; Yao, Shouzhuo] Hunan Normal Univ, Coll Chem & Chem Engn, Minist Educ, Key Lab Chem Biol & Tradit Chinese Med Res, Changsha 410081, Peoples R China published Photoinduced Charge Separation via the Double-Electron Transfer Mechanism in Nitrogen Vacancies g-C3N5/BiOBr for the Photoelectrochemical Nitrogen Reduction in 2020.0, Cited 32.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Due to the harsh reaction conditions, high energy consumption, and numerous carbon emissions of the traditional Haber-Bosch method, the fixation of nitrogen under environmentally friendly and milder conditions is of great importance. Recently, photoelectrochemical (PEC) strategies have attracted extensive attention, where the catalysts with the advantages of costeffectiveness and improved efficiency are critical for the nitrogen reduction reaction (NRR). Herein, we synthesized nitrogen vacancies that contained g-C3N5 (NV-g-C3N5) and combined with BiOBr to construct the p-n heterostructure NV-g-C3N5/BiOBr, in which the double-electron transfer mechanism was constructed. In one side, the nitrogen vacancies store the electrons coming from the g-C3N5 and provide for the nitrogen activation when needed; in addition, NV-g-C3N5/BiOBr further separates photoinduced electrons and holes because of the matched Z-shaped energy band structure. The double-electron transfer mechanism effectively retards the recombination of charge carriers and ensures the support of high-quality electrons, which results in excellent PEC NRR performance without the addition of noble metals. Although yields and durability are insufficient, the described double-electron transfer mechanism manifests the potential of the non-noble metal material in the PEC NRR, providing a foundation for the design of a more affordable and efficient photocathode in nitrogen reduction.

Safety of 1H-1,2,4-Triazol-5-amine. Welcome to talk about 61-82-5, If you have any questions, you can contact Li, MX; Lu, QJ; Liu, ML; Yin, P; Wu, CY; Li, HT; Zhang, YY; Yao, SZ or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Authors Sweidan, NI; El-Abadelah, MM; Nazer, MZ; Voelter, W in WALTER DE GRUYTER GMBH published article about THIENOPYRIDINONE ANTIBACTERIALS; BIOLOGICAL EVALUATION; PART; DERIVATIVES; ACIDS in [Voelter, Wolfgang] Univ Tubingen, Interfak Inst Biochem, Hoppe Seyler Str 4, D-72076 Tubingen, Germany; [Sweidan, Nuha, I] Univ Petra, Fac Art & Sci, Dept Chem, Amman 961343, Jordan; [El-Abadelah, Mustafa M.; Nazer, Musa Z.] Univ Jordan, Fac Sci, Dept Chem, Amman 11942, Jordan in 2020.0, Cited 23.0. Safety of 1H-1,2,4-Triazol-5-amine. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

Interaction of methyl 3-ethoxy-2-(2,5-dichloro-3-thenoyl)acrylate (I) with 3-aminopyrazole and 3- amino-1,2,4-triazole generated the respective pyrazolo [1,5-alpha]pyrimidine (4) and triazolo[1,5-alpha]pyrimidine (7). The formation of 4 entails selective and consecutive displacement of the 3-ethoxy and methoxy (ester) anions in I by 3-NH2 and 1-NH of 3-aminopyrazole. On the other hand, the formation of 7 implies selective displacement of 3-ethoxy in I by the ring-NH followed by cyclocondensation involving the keto group in I and 3-NH2 of aminotriazole. This latter selective displacement sequence is also followed by 3-amino-5-hydroxypyrazole in its reaction with I. The structures of the new compounds are supported by microanalytical and spectral data.

Safety of 1H-1,2,4-Triazol-5-amine. Welcome to talk about 61-82-5, If you have any questions, you can contact Sweidan, NI; El-Abadelah, MM; Nazer, MZ; Voelter, W or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Formula: C2H4N4. Recently I am researching about ANTIMICROBIAL POLYMERS; DRUG-RESISTANCE; BROAD-SPECTRUM; DESIGN; CHAIN; PEPTIDES; PROFILE; POTENT; AGENTS; CHARGE, Saw an article supported by the Ministerio de Economia y Competitividad of Spain [MAT2016-77345-C3-2-P]; VIPPITUS. Published in ELSEVIER in AMSTERDAM ,Authors: Rangel-Nunez, C; Ramirez-Trujillo, C; Hakkou, K; Suarez-Cruz, A; Molina-Pinilla, I; Bueno-Martinez, M. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

Novel linear cationic poly(amide aminotriazole)s (PATnD) with secondary amine groups in the backbone were obtained by using azide-alkyne 1,3-dipolar cycloaddition reactions: metal- and solvent-free (thermal conditions, PATTnD) or copper(I)-catalyzed (Sharpless conditions, PATCnD). PATnD were investigated in vitro against strains of E. coli, P. aeruginosa, S. aureus, and S. epidermidis. Hemolytic activity was tested using human red blood cells (hRBC), and very low or no hemolytic activity was observed. The cytotoxicity of PATnD polymers against Human Gingival Fibroblasts (HGnF) cells was concentration-dependent, and significant differences between PATT1D and PATC1D were observed. The ability of these polymers to induce resistance against both Grampositive and Gram-negative bacteria was also assessed. Studied bacterial strains acquired resistance to catalytic polymers (PATCnD) in initial passages meanwhile resistance to thermal polymers (PATTnD) appears in later passages, being the increase of the minimum inhibitory concentration lower than in catalytic polymers. This result, together with the higher biocidal capacity of thermal polymers compared to catalytic ones, seems to suggest an influence of the regiospecificity of the polymers on their antibacterial characteristics. This study also demonstrates that PAT1D polymers, which do not appear to have strong hydrophobic residues, can exert significant antimicrobial activity against Gram-positive bacteria such as S. epidermidis. This pair of polymers, PATC1D and PATT1D, displays the greatest antimicrobial activity while not causing significant hemolysis along with the lowest susceptibility for resistance development of the polymers evaluated.

Formula: C2H4N4. Welcome to talk about 61-82-5, If you have any questions, you can contact Rangel-Nunez, C; Ramirez-Trujillo, C; Hakkou, K; Suarez-Cruz, A; Molina-Pinilla, I; Bueno-Martinez, M or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics