Day: January 5, 2022

HPLC of Formula: C2H4N4. In 2019.0 J HETEROCYCLIC CHEM published article about MICROWAVE-ASSISTED SYNTHESIS; BIOLOGICAL-ACTIVITY; ANTIBACTERIAL ACTIVITY; DERIVATIVES; 1,2,4-TRIAZOLE; ANTIFUNGAL; RESISTANCE; INHIBITORS; PYRAZOLE; SYSTEMS in [El Azab, Islam H.; Gobouri, Adil A.; Altalhi, Tariq A.] Taif Univ, Fac Sci, Chem Dept, POB 888, At Taif 21974, Saudi Arabia in 2019.0, Cited 44.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

In our approach to synthesize bioactive molecules, a series of novel N-heterocycles were synthesized and evaluated for their in vitro antitumor activity against a panel of three human cancer cell lines, namely, human breast cancer cell line (MCF-7), human cervical cancer cell line (HeLa), and human prostate cancer PC-3. The majority of the tested compounds exhibited significant cytotoxic activity toward the tested tumor cell lines. Analogues 33, 34, 31, 38, 21, 23, 22, and 20 exhibited considerable cytotoxic activities comparable with standard drug 5-fuorouracil. Compound 33 displayed superior cytotoxicity with IC50 value of 4.12 +/- 1.21 mu g/mL against HeLa tumor cell line.

HPLC of Formula: C2H4N4. Welcome to talk about 61-82-5, If you have any questions, you can contact El Azab, IH; Gobouri, AA; Altalhi, TA or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Category: Triazoles. Ibrahim, MA; El-Kazak, AM in [Ibrahim, Magdy A.; El-Kazak, Azza M.] Ain Shams Univ, Fac Educ, Dept Chem, Cairo 11711, Egypt published Ring Opening and Recyclization Reactions with Chromone-3-carbonitrile in 2019.0, Cited 32.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Chemical transformations of chromone-3-carbonitrile (1) with some substituted hydrazines, namely, thiosemicarbazide, S-methyl/benzyldithiocarbazate, 7-chloro-4-hydrazinoquinoline, and 3-hydrazino-5,6-diphenyl-1,2,4-triazine, led to substituted pyrazoles 2, 5-8. Ring opening of carbonitrile 1 followed by recyclization with 3-amino-1,2,4-triazole and 2-aminobenzimidazole gave triazolo[1,5-a]pyrimidine 9 and pyrimido[1,2-a]benzimidazole 10, respectively. Treatment of carbonitrile 1 with some heterocyclic amines produced 2-amino-3-substituted-chromones 11 and 12. The novel 3-hydroxychromeno[4,3-b]pyrazolo[4,3-e]pyridin-5(1H)-one (13) was efficiently synthesized from the ring conversion of carbonitrile 1 with cyanoacetohydrazide. A mixture of chromeno[2,3-b]naphthyridine 14 and chromeno[4,3-b]pyridine 15 was obtained from base catalyzed transformation of carbonitrile 1 with malononitrile dimer. A diversity of novel annulated chromeno[2,3-b]pyridines 16-22 was also synthesized. Chromeno[2,3-b]pyrrole-2-carboxylate 23 was obtained from the reaction of carbonitrile 1 with ethyl chloroacetate. Structures of the new synthesized products were deduced on the basis of their analytical and spectral data.

Category: Triazoles. Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

I found the field of Materials Science very interesting. Saw the article Porous graphitic carbon nitride with controllable nitrogen vacancies: As promising catalyst for enhanced degradation of pollutant under visible light published in 2019.0. Safety of 1H-1,2,4-Triazol-5-amine, Reprint Addresses Zhang, YY (corresponding author), Hunan Normal Univ, Coll Chem & Chem Engn, Minist Educ, Key Lab Chem Biol & Tradit Chinese Med Res, Changsha 410081, Hunan, Peoples R China.. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

Carbon nitride (CN) materials are considered as promising photocatalysts due to the advantages of easy availability and visible light absorption. However, wide band gap and high recombination rates of electron-hole pairs of conventional CN materials remain the bottleneck of the photocatalysts. Therefore, it is necessary to develop an efficient strategy to narrow band gap of CN and accelerate its charge transfer. In addition, the introduction of nitrogen (N) vacancies is an efficient strategy to narrow band gap and reduce recombination rates of electron-hole pairs. Herein, a novel triazole ring-based graphite carbon nitride (g-CN) is developed by one step pathway of NaOH-assisted condensation of triazole rings for the first time. It is found that NaOH can control N vacancies and band gap of g-C3Nx. Meanwhile, the N vacancies of g-CN, gradually increase with the increasing concentration of NaOH in the range of 0.005-0.1 g, suppressing the recombination of photogenerated electron-hole pairs. The proposed g-C3N5 exhibits outstanding photocatalytical and photoelectrochemical performance. Therefore, the study highlights the significance of N vacancies in enhancing the photocatalytical and photoelectrochemical performance of promising g-C3N5. (C) 2015 Published by Elsevier Ltd.

Safety of 1H-1,2,4-Triazol-5-amine. Welcome to talk about 61-82-5, If you have any questions, you can contact Wang, HY; Li, MX; Li, H; Lu, QJ; Zhang, YY; Yao, SZ or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

SDS of cas: 61-82-5. I found the field of Chemistry very interesting. Saw the article Bioinspired Construction of a Nanozyme-Based H2O2 Homeostasis Disruptor for Intensive Chemodynamic Therapy published in 2020.0, Reprint Addresses Ren, JS; Qu, XG (corresponding author), Chinese Acad Sci, Changchun Inst Appl Chem, Lab Chem Biol, Changchun 130022, Jilin, Peoples R China.; Ren, JS; Qu, XG (corresponding author), Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Rare Earth Resource Utilizat, Changchun 130022, Jilin, Peoples R China.. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine.

The insufficient intracellular H2O2 level in tumor cells is closely associated with the limited efficacy of chemodynamic therapy (CDT). Despite tremendous efforts, engineering CDT agents with a straightforward and secure H2O2 supplying ability remains a great challenge. Inspired by the balance of H2O2 generation and elimination in cancer cells, herein, a nanozyme-based H2O2 homeostasis disruptor is fabricated to elevate the intracellular H2O2 level through facilitating H2O2 production and restraining H2O2 elimination for enhanced CDT. In the formulation, the disruptor with superoxide dismutase-mimicking activity can convert O-2(center dot-) to H2O2, promoting the production of H2O2. Simultaneously, the suppression of catalase activity and depletion of glutathione by the disruptor weaken the transformation of H2O2 to H2O. Thus, the well-defined system could perturb the H2O2 balance and give rise to the accumulation of H2O2 in cancer cells. The raised H2O2 level would ultimately amplify the Fenton-like reaction-based CDT efficiency. Our work not only paves a way to engineer alternative CDT agents with a H2O2 supplying ability for intensive CDT but also provides new insights into the construction of bioinspired materials.

SDS of cas: 61-82-5. Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Recently I am researching about HETEROJUNCTION PHOTOCATALYSTS; COMPOSITE; WATER; DEGRADATION; NANOTUBES; EVOLUTION; SEMICONDUCTORS; OXIDATION; REDUCTION; PHENOL, Saw an article supported by the ARC Discovery ProjectsAustralian Research Council [DP14010243, DP190103720]; Macquarie University iMQRTP scholarship. Published in PERGAMON-ELSEVIER SCIENCE LTD in OXFORD ,Authors: Kheradmand, A; Zhu, YX; Zhang, WW; Marianov, A; Jiang, YJ. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine. Formula: C2H4N4

Cobalt oxide (Co3O4) nanoparticles decorated on mesoporous carbon nitride (Co3O4/MCN) nanocomposites for photocatalytic hydrogen evolution were investigated in this work. MCN was prepared using 3-amino-1,2,4-triazole, high nitrogen content, as a single molecular carbon and nitrogen precursor and SiO2 nanoparticles as the hard template. Complementary characterization techniques were employed to understand the textural and chemical properties of the nanocomposites. The bare MCN showed high photocatalytic activity under visible light irradiation without using any co-catalyst. The photocatalytic activity of Co3O4/MCN with a Co3O4 mass content of 5 wt % presented two times higher than the bare MCN, which is attributed to the enhanced visible-light harvesting and more efficient charge separation. Mechanistic study shows lower electron-hole recombination rate, higher charge separation efficiency occurs after the formation of p-n type heterojunction. (C) 2019 Hydrogen Energy Publications LLC. Published by Elsevier Ltd. All rights reserved.

Formula: C2H4N4. Welcome to talk about 61-82-5, If you have any questions, you can contact Kheradmand, A; Zhu, YX; Zhang, WW; Marianov, A; Jiang, YJ or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

HPLC of Formula: C2H4N4. Li, JJ; Zhou, YN; Luo, ZH; Zhu, SP in [Li, Jin-Jin; Zhou, Yin-Ning; Zhu, Shiping] McMaster Univ, Dept Chem Engn, Hamilton, ON L8S 4L7, Canada; [Li, Jin-Jin; Zhou, Yin-Ning; Luo, Zheng-Hong] Shanghai Jiao Tong Univ, Sch Chem & Chem Engn, Dept Chem Engn, Shanghai 200240, Peoples R China; [Zhu, Shiping] Chinese Univ Hong Kong, Sch Sci & Engn, Shenzhen 518172, Peoples R China published A polyelectrolyte-containing copolymer with a gas-switchable lower critical solution temperature-type phase transition in 2019.0, Cited 50.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

A thermo-responsive copolymer with a gas-switchable LCST-type phase transition was synthesized by reversible addition-fragmentation chain transfer (RAFT) polymerization of N-isopropylacrylamide (NIPAM) and glycidyl methacrylate (GMA), followed by post-polymerization functionalization with sodium 3-amino-1,2,4-triazole (ATANa). Incorporating ionic moieties provides an elevated cloud point of 61 degrees C. Importantly, both CO2 and SO2 cause a reduction in the cloud point of the polymer solution. The CO2-triggered system can be easily and fully recovered to its initial state by introducing an inert gas (e.g. N-2), whereas the SO2-triggered system shows only partial recovery. The pH-dependent phase transition behaviors confirm that the gas bubbling-induced pH changes contribute to the gas-switchable cloud point of P(NIPAM-co-(GMA-ATANa)). In addition, P(NIPAM-co-(GMA-ATA)) (ATA: 3-amino-1,2,4-triazole), a counterpart of P(NIPAM-co-(GMA-ATANa)), was prepared and the relevant solution phase transition behavior was studied. Its cloud point shift in response to gas bubbling and pH adjustment is opposite to that of P(NIPAM-co-(GMA-ATANa)), indicating that the latter does not result from the protonation of amidine groups. Alternatively, a reversible H+-induced decrease in hydrophilicity was thus proposed. This contribution enriches the family of thermo-responsive polymers by introducing gas-sensitive polyelectrolytes and also broadens the scope of gas-responsive smart materials.

Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.. HPLC of Formula: C2H4N4

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

An article Synthesis of novel AgCl loaded g-C3N5 with ultrahigh activity as visible light photocatalyst for pollutants degradation WOS:000501784200050 published article about FABRICATION; CATALYSTS in [Vadivel, S.; Hariganesh, S.; Maruthamani, D.; Kumaravel, M.] PSG Coll Technol, Dept Chem, Coimbatore 641004, Tamil Nadu, India; [Paul, Bappi] Natl Inst Technol Silchar, Dept Chem, Silchar 788010, Assam, India; [Rajendran, Saravanan] Univ Tarapaca, Dept Mech Engn, Fac Engn, Avda Gen Velasquez, Arica 1775, Chile; [Habibi-Yangjeh, Aziz] Univ Mohaghegh, Dept Chem, Fac Sci, POB 179, Ardebil, Iran in 2020.0, Cited 22.0. Product Details of 61-82-5. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

We report the photocatalytic property of a novel AgCl loaded carbon nitride (AgCl/g-C3N5) composite was prepared by a simple precipitation route. The brown colored g-C3N5 was synthesized by a nano-hard templating method using 3-amino-1,2,4-triazole precursor. The morphology, crystallinity and optical properties of the AgCl/g-C3N5 composite were characterized using the X-ray diffraction analysis (XRD), transmission electron microscopy (TEM), and diffuse reflectance spectroscopy (UV-DRS) spectroscopy. The rhodamine B (RhB) removal efficiency was reached 96% within 30 min, which could be attributed to the effective formation of a heterojunction and excellent visible light absorption of AgCl by g-C3N5 incorporation.

Product Details of 61-82-5. Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

HPLC of Formula: C2H4N4. In 2019.0 MOLECULES published article about BIOLOGICAL EVALUATION; BIS-THIAZOLES; ANTI-HCV; INHIBITORS; DESIGN; IDENTIFICATION; POTENT; AGENTS; THIADIAZOLES; COMPLEXES in [Althagafi, Ismail; El-Metwaly, Nashwa; Farghaly, Thoraya A.] Umm Al Qura Univ, Fac Sci Appl, Dept Chem, Mecca 21514, Saudi Arabia; [El-Metwaly, Nashwa] Mansoura Univ, Dept Chem, Fac Sci, Mansoura 002050, Egypt; [Farghaly, Thoraya A.] Cairo Univ, Dept Chem, Fac Sci, Giza 12613, Egypt in 2019.0, Cited 41.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Based on the extensive biological activities of thiazole derivatives against different types of diseases, we are interested in the effective part of many natural compounds, so we synthesized a new series of compounds containing di-, tri- and tetrathiazole moieties. The formation of such derivatives proceeded via reaction of 2-bromo-1-(4-methyl-2-(methylamino)thiazol-5-yl)ethan-1-one with heterocyclic amines, o-aminothiophenol and thiosemicarbazone derivatives. The structure and mechanistic pathways for all products were discussed and proved based on spectral results, in addition to conformational studies. Our aim after the synthesis is to investigate their antimicrobial activity against various types of bacteria and fungi species. Preceeding such an investigation, a molecular docking study was carried out with selected conformers, as representative examples, against three pathogen-proteins. This preliminary stage could support the biological application. The potency of these compounds as antimicrobial agents has been evaluated. The results showed that derivatives which have di- and trithiazole rings displayed high activity that exceeds the used standard antibiotic.

HPLC of Formula: C2H4N4. Welcome to talk about 61-82-5, If you have any questions, you can contact Althagafi, I; El-Metwaly, N; Farghaly, TA or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Yuan, S; Feng, SQ; Li, AQ; Zuo, JH; Zhang, DQ; Xing, YJ; Xie, ZY; Yu, B; Liu, HM in [Yuan, Shuo; Feng, Si-Qi; Li, An-Qi; Zuo, Jia-Hui; Zhang, Dan-Qing; Xing, Yu-Jie; Yu, Bin; Liu, Hong-Min] Zhengzhou Univ, Sch Pharmaceut Sci, Zhengzhou 450001, Peoples R China; [Yuan, Shuo; Feng, Si-Qi; Li, An-Qi; Zuo, Jia-Hui; Zhang, Dan-Qing; Xing, Yu-Jie; Yu, Bin; Liu, Hong-Min] Zhengzhou Univ, Key Lab Adv Drug Preparat Technol, Minist Educ, Zhengzhou 450001, Peoples R China; [Xie, Zhiyu] Xuchang Univ, Coll Chem & Mat Engn, 88 Bayi Rd, Xuchang 461000, Henan, Peoples R China published Design and synthesis of new indole containing biaryl derivatives as potent antiproliferative agents in 2021.0, Cited 26.0. Name: 1H-1,2,4-Triazol-5-amine. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

A new series of indole containing biaryl derivatives were designed and synthesized, and further biological evaluations of their antiproliferative activity against cancer cell lines (MGC-803 and TE-1 cells) were also conducted. Of these synthesized biaryls, compound 4-methyl-2-((5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl) methyl)quinazoline (23) performed as the most potent antiproliferative agent that inhibited cell viability of MGC-803 cells with an IC50 value of 8.28 mu M. In addition, investigation of mechanism exhibited that the compound 4-methyl-2-((5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)methyl)quinazoline (23) could inhibit the expression of c-Myc and glycolysis related proteins, decrease the ATP and lactate production, and further induce apoptosis by activating the AMP-activated protein kinase (AMPK) and p53 signaling pathways.

Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.. Name: 1H-1,2,4-Triazol-5-amine

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

In 2021.0 PLANT SCI published article about LOCUS-T; FT PROTEIN; FLORAL INDUCTION; SIGNAL; PHLOEM; ACTIVATION; IDENTITY; GENES; ACTS in [Zhang, Liang; Liu, Fangbing; Song, Shiyong] Chinese Acad Sci, CAS Key Lab Plant Germplasm Enhancement & Special, Wuhan Bot Garden, Wuhan 430074, Hubei, Peoples R China; [Zhang, Liang; Liu, Fangbing] Univ Chinese Acad Sci, Beijing 100049, Peoples R China; [Zhang, Liang; Liu, Fangbing; Song, Shiyong] Chinese Acad Sci, Ctr Econ Bot, Core Bot Gardens, Wuhan 430074, Peoples R China; [Zhang, Fan; Shen, Jun; Wang, Jiaxuan; Jiang, Meng; Chen, Ying; Song, Shiyong] Zhejiang Univ, Inst Crop Sci, State Key Lab Rice Biol, Zhejiang Prov Key Lab Crop Genet Resources, Hangzhou 310058, Peoples R China; [Zhang, Dasheng] Chinese Acad Sci, Shanghai Chenshan Bot Garden, Shanghai Chenshan Plant Sci Res Ctr, Shanghai 201602, Peoples R China; [Yang, Pingfang] Hubei Univ, Sch Life Sci, State Key Lab Biocatalysis & Enzyme Engn, Wuhan 430062, Peoples R China in 2021.0, Cited 40.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. Application In Synthesis of 1H-1,2,4-Triazol-5-amine

In higher plants, floral signals are mainly collected and transduced to FLOWERING LOCUS T (FT) in Arabidopsis and its orthologues. The movement of FT from leaves to the shoot apical meristem (SAM) is partially mediated by FT-INTERACTING PROTEIN1 (FTIP1). Although the functions of OsFTIP1 in rice and DOFTIP1 in orchid in FT transport have also been investigated, the FTIP1 homologue in lotus (Nelumbo nucifera Gaertn.), a type of horticultural plant with high economic and cultural value, has not been isolated, and the mechanism of NnFT1 transport has not been explored. Here, we revealed that NnFTIP1 mediates the transport of NnFT1 in ectopic transgenic lines in Arabidopsis. Overexpression of NnFTIP1 in the ftip1-1 background rescued the late flowering phenotype of ftip1-1, indicating that NnFTIP1 has a conserved function as FTIP1. NnFTIP1 and NnFT1 share similar tissue expression patterns and subcellular localization. NnFTIP1 and NnFT1 interact both in vitro and in vivo. In addition, NnFTIP1 affects NnFT1 transport from leaves to the SAM. Furthermore, we found that NnUOF8, a MYB-like transcription factor, directly regulates the expression of NnFTIP1. Our results suggest that the functions of FTIP1 and FT are conserved during evolution in flowering plants.

Application In Synthesis of 1H-1,2,4-Triazol-5-amine. Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics