Month: February 2022

Category: Triazoles. Authors Wang, GY; Zheng, T; Zhang, SQ; Ye, JW; Ning, GL in ELSEVIER published article about in [Ye, Junwei; Ning, Guiling] Dalian Univ Technol, State Key Lab Fine Chem, 2 Linggong Rd, Dalian 116012, Peoples R China; Dalian Univ Technol, Sch Chem Engn, 2 Linggong Rd, Dalian 116012, Peoples R China in 2021.0, Cited 47.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

A novel pyridinium salt derivative, 2,3,4,5,6-pentaphenyl-1-(1H-1,2,4-triazol-3-yl)pyridinium perchlorate (1) has been designed and synthesized by using pyrylium perchlorate and 3-amino-1H-1,2,4-triazole as ingredients, which can be exploited for the binding and specific sensing of anion via hydrogen bonds. Compound 1 exhibits intense blue emission in solution with maximum emission at 469 nm with a red shift relative to that (426 nm) of solid state. The luminescence intensity of 1 could be selectively and sensitivity quenched with acetate ion and fluorine ion among various anions including F-, Cl-, Br-, I-, AcO- and NO3-. Furthermore, the possible detection mechanism was investigated. This work could contribute a credible potential sensing application of 1,2,4-triazolyl substituted pentaphenylpyridinium salts towards the specific anions in biological and environmental concerns. (C) 2021 Elsevier B.V. All rights reserved.

Category: Triazoles. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Wang, GY; Zheng, T; Zhang, SQ; Ye, JW; Ning, GL or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article Screening for extractables in additive-manufactured acrylonitrile butadiene styrene orthopedic cast published in 2020.0. Recommanded Product: 61-82-5, Reprint Addresses Wickramasekara, S (corresponding author), US FDA, DBCMS, OSEL, CDRH, 10903 New Hampshire Ave,Bldg 64,Rm 3064, Silver Spring, MD 20993 USA.. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

The use of additive-manufactured components in medical applications, specifically medical devices (e.g., orthopedic casts), has increased in recent years. Such devices may be fabricated at the point of care using consumer-grade additive manufacturing. Limited studies have been conducted to evaluate the extractable substances of these devices. Chemical characterization followed by toxicological risk assessment is one means of evaluating safety of devices. This study was designed to determine the extractables profile of additive-manufactured materials according to filament grade and post-processing method. Feedstocks for additive manufacturing were tested as filament and manufactured casts, while the cast from consumer-grade filament (CGF) was post-processed. Samples were extracted using three solvents of varying polarities. Extracts were analyzed by gas chromatography/mass spectrometry (GC/MS) and liquid chromatography/mass spectrometry (LC/MS) techniques. In GC/MS analysis, isopropanol extracts generated fewer compound identifications for USP Class VI filament (USPF)-based casts (3) compared with the respective filament (17) while hexane generated the most compound identifications for the finished cast manufactured from CGF. CGF was found to have the highest number of nonvolatile extractables for isopropanol (15) and hexane (34) by positive ion LC/MS. Additionally, CGF produced more non-polar extractables in hexane than the USPF. A known polymer byproduct and potential genotoxicant, styrene acrylonitrile (SAN) trimer, was one of the compounds identified in both GC/MS and LC/MS at quantities ranging from 19 to 270 mu g g(-1). Overall these results suggested that the extractables profile was affected by the filament material, printing procedure, and post-processing method.

Recommanded Product: 61-82-5. Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Recently I am researching about MECHANICAL-PROPERTIES; COMPOSITE RESIN; THERMAL-DEGRADATION; FILLER MORPHOLOGY; FLEXURAL STRENGTH; WEAR; PARTICLES; MEMBRANES; FRACTION; BEHAVIOR, Saw an article supported by the . COA of Formula: C2H4N4. Published in SAGE PUBLICATIONS LTD in LONDON ,Authors: Yushau, US; Almofeez, L; Bozkurt, A. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

This article is focused on the preparation and characterization of functional nanosilica incorporated dental resins with better mechanical, cytotoxicity, sorption, and solubility properties. Silica nanoparticles were synthesized via Stober method and were functionalized with 3-amino-1,2,4-triazole. Dental nanocomposites were produced by embedding the functionalized nanosilica into bisphenol-A-glycidyl methacrylate/triethylene glycol dimethacrylate matrix to form B1-B6 series. This was achieved by mechanical mixing of the monomer (50:50 wt%), filler (10-60 wt%), initiator combination (CQ/EDMAB:O. 1 :0.4 wt%) and then followed by LED light curing (wavelength: 450-500 nm, power density:1000 mW cm(-2)) for 60 s. Fourier transform infrared spectroscopy, scanning electron microscopy, and thermogravimetric analysis techniques were used for characterization of the materials. Cytotoxicity tests were performed to evaluate cell viability and mechanical tests were done to check mechanical strength and stability of the materials. The mean sorption and solubility values of the materials were measured by making a series of experiments on different composite formulations.

About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Yushau, US; Almofeez, L; Bozkurt, A or concate me.. COA of Formula: C2H4N4

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

SDS of cas: 61-82-5. Authors Ben Ali, A; El Bakri, Y; Lai, CH; Sebhaoui, J; El Ghayati, L; Essassi, E; Mague, JT in INT UNION CRYSTALLOGRAPHY published article about in [Ben Ali, Abdelkader] Mohammed V Univ Rabat, Fac Sci, Ctr Sci Mat, Lab Chim Appl Mat, Ave Ibn,BP 1014, Rabat, Morocco; [El Bakri, Youness; Sebhaoui, Jihad; El Ghayati, Lhoussaine; Essassi, El Mokhtar] Univ Mohammed 5, Fac Sci, Ctr Rech Sci Med, URAC 21,Pole Competence Pharmacochim, Av Ibn Battouta,BP 1014, Rabat, Morocco; [Lai, Chin-Hung] Chung Shan Med Univ, Dept Med Appl Chem, Taichung 40241, Taiwan; [Lai, Chin-Hung] Chung Shan Med Univ Hosp, Dept Med Educ, Taichung 40241, Taiwan; [Mague, Joel T.] Tulane Univ, Dept Chem, New Orleans, LA 70118 USA in 2019.0, Cited 38.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

In the title molecule, C13H16N4O3, the mean planes of the phenyl and triazole rings are nearly perpendicular to one another as a result of the intramolecular C-H center dot center dot center dot O and C-H center dot center dot center dot pi(ring) interactions. In the crystal, layers parallel to (101) are generated by O-H center dot center dot center dot N, N-H center dot center dot center dot O and N-H center dot center dot center dot N hydrogen bonds. The layers are connected by inversion-related pairs of C-H center dot center dot center dot O hydrogen bonds. The experimental molecular structure is close to the gas-phase geometryoptimized structure calculated by DFT methods. Hirshfeld surface analysis indicates that the most important interaction involving hydrogen in the title compound is the H center dot center dot center dot H contact. The contribution of the H center dot center dot center dot O, H center dot center dot center dot N, and H center dot center dot center dot H contacts are 13.6, 16.1, and 54.6%, respectively.

SDS of cas: 61-82-5. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Ben Ali, A; El Bakri, Y; Lai, CH; Sebhaoui, J; El Ghayati, L; Essassi, E; Mague, JT or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

HPLC of Formula: C2H4N4. In 2021.0 CHEM PHYS published article about GOLD NANOPARTICLES; NANOPOROUS CARBON; POROUS CARBON; SULFUR; SENSOR in [Zhou, Shenghai; Xu, Hongbo; Liu, Jinyu; Wei, Yajun; Ma, Xinhuan; Han, Zhimin; Chen, Hongli] Hebei Normal Univ Nationalities, Coll Chem & Chem Engn, Chengde 067000, Peoples R China in 2021.0, Cited 45.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

N-doped carbon nanopipe-arrayed mesoporous carbon (N-CMK-5) with double-pore system, large surface area (992 m(2)/g), and high nitrogen amount (5.2 at.%) was synthesized by a simplified template route. In this route, mesoporous silica was directly used instead of using time-consuming aluminosilicate as a template and the carbonization process occurred in a nitrogen atmosphere instead of a vacuum. Furthermore, CMK-3, N-doped CMK-3, and CMK-5 ordered mesopomus carbons (OMCs) were compared with the as-prepared N-doped CMK-5 (N-CMK-5) to investigate the effect of microstructure on the electrochemical activity of OMCs. N-CMK-5 exhibited higher electrochemical activity than the other OMCs because it has more exposed defective sites and nitrogen active species. The developed N-CMK-5-based electrochemical sensor showed good practical application for the electrochemical detection of pesticide amitrole in real water sample. This work contributes a simplified route to synthesize tubular N-CMK-5 carbon and provides valuable information on the design of high-performance carbon electrode materials.

Welcome to talk about 61-82-5, If you have any questions, you can contact Zhou, SH; Xu, HB; Liu, JY; Wei, YJ; Ma, XH; Han, ZM; Chen, HL or send Email.. HPLC of Formula: C2H4N4

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Quality Control of 1H-1,2,4-Triazol-5-amine. Authors Tkachenko, IG; Komykhov, SA; Gladkov, ES; Musatov, VI; Chebanov, VA; Desenko, SM in SPRINGER published article about in [Tkachenko, Irina G.; Komykhov, Sergey A.; Gladkov, Eugene S.; Musatov, Vladimir I.; Chebanov, Valentyn A.; Desenko, Sergey M.] Natl Acad Sci Ukraine, Inst Single Crystals, State Sci Inst, 60 Nauky Ave, UA-61072 Kharkov, Ukraine; [Tkachenko, Irina G.; Komykhov, Sergey A.; Gladkov, Eugene S.; Chebanov, Valentyn A.; Desenko, Sergey M.] Kharkov Natl Univ, 4 Svobody Sq, UA-61022 Kharkov, Ukraine; [Tkachenko, Irina G.] Minist Internal Affairs Ukraine, Kharkiv Forens Sci Ctr, 32 Kovtuna St, UA-61036 Kharkov, Ukraine in 2019.0, Cited 22.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

Three-component reaction of 3-amino-1H-1,2,4-triazole or 5-amino-2H-1,2,3-triazole derivatives, acetaldehyde, and 1,3-dicarbonyl compounds (acetylacetone or -keto esters) in water under microwave irradiation leads to regioselective formation of 4,7-dihydro[1,2,4]-triazolo- and 4,7-dihydro[1,2,3]triazolo[1,5-a]pyrimidines. Using ethyl 4,4,4-trifluoro-3-oxobutanoate as 1,3-dicarbonyl compound under the same conditions allows to obtain the corresponding 5-hydroxy-4,5,6,7-tetrahydro derivatives, which fail to dehydrate in the reaction medium.

Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.. Quality Control of 1H-1,2,4-Triazol-5-amine

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Computed Properties of C2H4N4. In 2020.0 J HETEROCYCLIC CHEM published article about THIAZOLE DERIVATIVES; MOLECULAR DESIGN; ANTITUMOR; AGENTS in [Abed, Nader A.; Hammouda, Mohamed M.; Ismail, Mohamed A.; Abdel-Latif, Ehab] Mansoura Univ, Fac Sci, Chem Dept, Mansoura 35516, Egypt in 2020.0, Cited 37.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

The chemical performance of 5-bromo-2-(bromoacetyl)-thiophene (1) was tested toward the reaction with numerous bi-nucleophilic reagents (namely; 2-aminobenzothiazoles, 2-aminothiazole, 2-aminotetrazole, 2-aminotriazole, 2-aminopyridines, 2-aminobenzimidazole ando-phenylenediamine). Therefore, a series of bridged nitrogen heterocycles bearing thiophene moiety3,5,7,9,11,13and15, respectively was synthesized. In addition, the reaction of 5-bromo-2-(bromoacetyl)-thiophene with the thiocarbamoyl compounds17,19and/or24afforded the corresponding thienyl-thiazoles18or dithien-2-yl ketones20and25, based on the reaction conditions. Treatment of1with 2-mercapto-4,6-dimethylnicotinonitrile was achieved to obtain the target dithien-2-yl ketone28. The new synthesized scaffolds were examined for their antioxidant activity by means of ABTS antioxidant assay. The thienyl-thiazole scaffold18cand 2-((2-[thiophen-2-yl]-2-oxoethyl)thio)nicotinonitrile derivative27displayed a reasonable radical scavenging activity.

Computed Properties of C2H4N4. Welcome to talk about 61-82-5, If you have any questions, you can contact Abed, NA; Hammouda, MM; Ismail, MA; Abdel-Latif, E or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Computed Properties of C2H4N4. In 2019.0 INT J MOL SCI published article about HISTONE H2AX; BRCT DOMAINS; S-PHASE; DNA; PROTEIN; REPAIR; MDC1; LOCALIZATION; LIGASE; REGION in [Krieger, Kimiko L.; Hu, Wen-Feng; Ripperger, Tyler; Woods, Nicholas T.] Univ Nebraska Med Ctr, Fred & Pamela Buffett Canc Ctr, Eppley Inst Res Canc & Allied Dis, Omaha, NE 68198 USA; [Hu, Wen-Feng] Univ Nebraska Med Ctr, Coll Med, Dept Emergency Med, Omaha, NE 68198 USA; [Ripperger, Tyler] Univ Arizona, Dept Immunobiol, Coll Med, Tucson, AZ 85724 USA in 2019.0, Cited 43.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Deleterious mutations in Breast Cancer 1 (BRCA1) are associated with an increased risk of breast and ovarian cancer. Mutations in the tandem BRCA1 C-terminal (tBRCT) protein domain disrupt critical protein interactions required for the faithful repair of DNA through homologous recombination, which contributes to oncogenesis. Our studies have identified RICTOR, PRR5, and SIN1 subunits of the mammalian target of rapamycin complex 2 (mTORC2) as interacting partners with the tBRCT domain of BRCA1 leading to the disruption of the mTORC2 complex. However, the interplay between mTORC2 signaling and BRCA1 function in the DNA damage response (DDR) remains to be determined. In this study, we used protein interaction assays to determine the binary interactions between the tBRCT domain and mTORC2 subunits, evaluated the impact of mTOR inhibition on the transcriptional function of the tBRCT, evaluated the impact of mTOR signaling on BRCA1 recruitment to DNA damage-induced foci and determined the breast cancer cell line response to mTOR inhibition dependent upon BRCA1 expression and mutation. This study determined that PRR5, RICTOR, and SIN1 could each independently interact with the BRCA1 tBRCT. Inhibition of mTORC1, but not mTORC1/2, increases BRCA1 transcriptional activation activity. Treatment with pan-mTOR inhibitor PP242 diminishes DNA damage-induced gamma H2AX and BRCA1 foci formation. Breast cancer cells lacking expression of functional BRCA1 are more sensitive to mTOR inhibitors. These data suggest that mTOR signaling is required for BRCA1 response to DNA damage and breast cancer cells lacking BRCA1 are more sensitive to pan-mTOR inhibition. This work suggests chemotherapeutic strategies using mTOR inhibitors could be tailored for patients that lack functional BRCA1.

Welcome to talk about 61-82-5, If you have any questions, you can contact Krieger, KL; Hu, WF; Ripperger, T; Woods, NT or send Email.. Computed Properties of C2H4N4

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Maza, S; Kijatkin, C; Bouhidel, Z; Pillet, S; Schaniel, D; Imlau, M; Guillot, B; Cherouana, A; Bendeif, EE in [Maza, Soumeya; Bouhidel, Zakaria; Cherouana, Aoutef] Univ Freres Mentouri Constantine 1, Dept Chim, Unite Rech Chim Environm & Mol Struct CHEMS, Constantine 25000, Algeria; [Maza, Soumeya; Pillet, Sebastien; Schaniel, Dominik; Guillot, Benoit; Bendeif, El-Eulmi] Univ Lorraine, CRM2, CNRS, Nancy, France; [Kijatkin, Christian; Imlau, Mirco] Osnabruck Univ, Sch Phys, D-49076 Osnabruck, Germany; [Kijatkin, Christian; Imlau, Mirco] Osnabruck Univ, Res Ctr Cellular Nanoanalyt, CellNanOs, D-49076 Osnabruck, Germany published Synthesis, structural investigation and NLO properties of three 1,2,4-triazole Schiff bases in 2020.0, Cited 60.0. SDS of cas: 61-82-5. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

We report in this work the synthesis, crystal structures analyses, and nonlinear-optical (NLO) properties of three Schiff bases with halogens and triazole moieties: (E)-1-(4-bromophenyl)-N-(1H-1,2,4-triazol-3yl)methanimine L1, (E)-1-(4-bromophenyl)-N-(4H-1,2,4-triazol-3-yl)methanimine L2, and (E)-1-(4chlorophenyl)-N-(4H-1,2,4-triazol-3-yl)methanimine L3. The three molecules are built on the basis of the same backbone formed by two aromatic rings (phenyl and triazole) linked by imine bridge. The two first compounds L1 and L2 contain tautomers of the Schiff base, where a phenyl ring is substituted by a bromine atom. The third one, L3, is similar to L2 but contains a chlorine atom instead of bromine. In crystals formed by these three Schiff bases the three dimensional networks are formed by supramolecular interactions such as hydrogen bonds, C-X…pi and X…X (X = Cl or Br) contacts. Complementary Hirshfeld surface analyses were carried out to investigate and quantify the contributions of the different intermolecular interactions within the supramolecular assemblies. These analyses reveal that the main contributions in the studied compounds are provided by the H center dot center dot center dot H and N center dot center dot center dot H interactions that represent-53% (for L1),-49% (for L2) and-50% (for L3) of the total contributions to the Hirshfeld surface. The nonlinear optical properties are investigated by nonlinear diffuse femtosecond-pulse reflectometry and are compared with those of the reference material LiNbO3, in particular regarding the temporal evolution. (C) 2020 Elsevier B.V. All rights reserved.

About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Maza, S; Kijatkin, C; Bouhidel, Z; Pillet, S; Schaniel, D; Imlau, M; Guillot, B; Cherouana, A; Bendeif, EE or concate me.. SDS of cas: 61-82-5

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Recommanded Product: 1H-1,2,4-Triazol-5-amine. In 2019.0 CHEM HETEROCYCL COM+ published article about ONE-POT SYNTHESIS; BUILDING-BLOCKS; HYDRAZINE; COMPLEXES; EFFICIENT; DERIVATIVES; LIGAND; YLIDE in [Kudyakova, Yulia S.; Slepukhin, Pavel A.; Burgart, Yanina V.; Saloutin, Victor I.; Bazhin, Denis N.] Russian Acad Sci, Ural Branch, Postovsky Inst Organ Synth, 22 S Kovalevskoi,20 Akad Skaya St, Ekaterinburg 620990, Russia; [Onoprienko, Aleksandra Ya.; Slepukhin, Pavel A.; Burgart, Yanina V.; Saloutin, Victor I.; Bazhin, Denis N.] Ural Fed Univ, 19 Mira St, Ekaterinburg 620002, Russia in 2019.0, Cited 53.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Five- and six-membered fluorine-containing azaheterocycles were synthesized based on available furan-3(2H)-ones, and the influence of the nature of the fluoroalkyl substituent on the direction of the chemical transformations by the action of N,N- and N,O-binucleophiles was revealed.

Recommanded Product: 1H-1,2,4-Triazol-5-amine. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Kudyakova, YS; Onoprienko, AY; Slepukhin, PA; Burgart, YV; Saloutin, VI; Bazhin, DN or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics