Day: November 1, 2022

Chavan, Omprakash S. published an article in 2022, the title of the article was Comparative study of various synthetic methods of 1,2,3-triazoles via click reaction: a mini review.Recommanded Product: 4-(p-Tolyl)-1H-1,2,3-triazole And the article contains the following content:

Different derivatives of azides were condensed with different derivatives of terminal alkynes via click condensation reaction to form resp. derivatives of 1,2,3-triazoles in various reaction conditions. Present paper deals with the comparative study of synthesis of derivatives of 1,2,3-triazoles with respect to yield, reaction time and reaction conditions. All products were characterized by spectral data and elemental anal. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Recommanded Product: 4-(p-Tolyl)-1H-1,2,3-triazole

The Article related to alkyne azide condensation reaction green chem, triazole preparation, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Recommanded Product: 4-(p-Tolyl)-1H-1,2,3-triazole

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

On February 29, 2016, Wu, Luyong; Wang, Xianghui; Chen, Yuxue; Huang, Qinglan; Lin, Qiang; Wu, Mingshu published an article.Recommanded Product: 4-(p-Tolyl)-1H-1,2,3-triazole The title of the article was 4-Aryl-NH-1,2,3-Triazoles via Multicomponent Reaction of Aldehydes, Nitroalkanes, and Sodium Azide. And the article contained the following:

4-Aryl-NH-1,2,3-triazoles are valuable compounds in organic chem. and pharmaceutical chem. In this paper, we describe a novel multicomponent reaction of aldehydes, nitroalkanes, and sodium azide for the synthesis of 4-aryl-NH-1,2,3-triazoles. In this transformation, it was found that both the slow addition of nitroalkane and the presence of NaHSO3/Na2SO3 are advantageous to promote the reaction results. Addnl., a series of aldehydes and nitro compounds were investigated. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Recommanded Product: 4-(p-Tolyl)-1H-1,2,3-triazole

The Article related to aryl triazole multicomponent preparation aldehyde nitroalkane sodium azide, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Recommanded Product: 4-(p-Tolyl)-1H-1,2,3-triazole

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

On August 7, 2008, Kalisiak, Jaroslaw; Sharpless, K. Barry; Fokin, Valery V. published an article.Product Details of 5301-96-2 The title of the article was Efficient Synthesis of 2-Substituted-1,2,3-triazoles. And the article contained the following:

In this three-component reaction, alkynes undergo a CuSO4-catalyzed cycloaddition with sodium azide and formaldehyde to yield 2-hydroxymethyl-2H-1,2,3-triazoles, which are useful intermediates that can be readily converted to polyfunctional mols. The hydroxymethyl group can also be removed, providing convenient access to NH-1,2,3-triazoles. The reaction is exptl. simple and readily scalable. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Product Details of 5301-96-2

The Article related to triazole preparation, copper catalyst cycloaddition alkyne azide formaldehyde, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Product Details of 5301-96-2

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

On February 16, 2018, Ke, Fang; Xu, Yiwen; Zhang, Peng; Lin, Xiaoyan; Xu, Jianhua; Lin, Chen published a patent.Computed Properties of 5301-96-2 The title of the patent was Catalytic synthesis method of 4-aryl-1H-1,2,3-triazole derivative under microwave irradiation. And the patent contained the following:

A process for preparation of 4-aryl-1H-1,2,3-triazole derivative I (R = halo, Me, Et, i-Pr, Bu, nitro, acetyl, etc.) under microwave irradiation is disclosed. The process comprises cyclization of 2-nitroolefin with sodium azide under catalysis of trifluoromethanesulfonic acid (TfOH) in pyridine by microwave irradiation at 50-80° and 100-250 W for 10-30 min tp generate the product. The process has the advantages of mild reaction condition, simple operation, high yield and safety, low cost and environmental protection. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Computed Properties of 5301-96-2

The Article related to aryl triazole derivative preparation catalytic cyclization microwave irradiation, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Computed Properties of 5301-96-2

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Alves, Tania M. F.; Jardim, Guilherme A. M.; Ferreira, Marco A. B. published an article in 2021, the title of the article was A green metal-free “one-pot” microwave assisted synthesis of 1,4-dihydrochromene triazoles.HPLC of Formula: 5301-96-2 And the article contains the following content:

The synthesis of several 4-aryl-1,4-dihydrochromene-triazoles I (R1 = H, 8-Cl, 8-Br, 8-t-Bu, 6-OEt; R2 = Ph, 2-MeC6H4, 3-O2NC6H4, etc.) was achieved via a metal-free “one-pot” procedure using PEG400 as the sole solvent in an eco-friendly process. Using microwave irradiation, the triazole derivatives were obtained in good yields and short reaction times starting from readily accessible building blocks. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).HPLC of Formula: 5301-96-2

The Article related to dihydrochromene triazole preparation green chem microwave irradiation metal free, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.HPLC of Formula: 5301-96-2

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

On January 31, 2016, Zhang, Hui; Dong, Dao-Qing; Wang, Zu-Li published an article.Reference of 4-(p-Tolyl)-1H-1,2,3-triazole The title of the article was Direct Synthesis of N-Unsubstituted 4-Aryl-1,2,3-triazoles Mediated by Amberlyst-15. And the article contained the following:

Aryltriazoles I [Ar is (un)substituted Ph, 2-thienyl] were prepared by reaction of nitrooelefins ArCH:CH2 with NaN3 promoted by Amberlyst-15. The method is highly efficient and the promoter can be recycled and reused up to eight times without any reduction in its catalytic activity. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Reference of 4-(p-Tolyl)-1H-1,2,3-triazole

The Article related to triazole phenyl preparation nitrostyrene cycloaddition azide catalyst amberlyst 15, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Reference of 4-(p-Tolyl)-1H-1,2,3-triazole

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Yan, Wuming; Ye, Xiaohan; Weise, Keith; Petersen, Jeffrey L.; Shi, Xiaodong published an article in 2012, the title of the article was Synthesis of allene triazole through iron catalyzed regioselective addition to propargyl alcohols.Safety of 4-(p-Tolyl)-1H-1,2,3-triazole And the article contains the following content:

Allene triazole derivatives were successfully synthesized through iron catalyzed regioselective triazole addition to tertiary propargyl alcs. The reaction proceeds under mild conditions, giving the desired allene-triazoles in good to excellent yields (up to 96%). The resulting allene-triazoles were confirmed by X-ray crystallog. and indicated improved stability. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Safety of 4-(p-Tolyl)-1H-1,2,3-triazole

The Article related to allene triazolyl preparation regioselective addition triazole propynol iron catalyst, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Safety of 4-(p-Tolyl)-1H-1,2,3-triazole

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

On April 30, 2008, Lu, Li-Hui; Wu, Jia-Hao; Yang, Chia-Hsi published an article.Electric Literature of 5301-96-2 The title of the article was Preparation of 1H-1,2,3-triazoles by cuprous ion mediated cycloaddition of terminal alkyne and sodium azide. And the article contained the following:

1H-1,2,3-triazoles were prepared in good yield by the reaction of terminal alkyne and sodium azide in the presence of cuprous chloride at a temperature higher than 70 °C. The alkyne was unactivated and the reaction was carried out under inert gas. At room temperature, the reaction first gave a Cu(I)-azide complex which was converted to a Cu-alkyne complex when the temperature was raised to higher than 70 °C. The reaction of Cu(I)-alkyne complex and azide ion dissociated from or coordinated to Cu(I) then gave 1H-1,2,3-triazoles. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Electric Literature of 5301-96-2

The Article related to alkyne cycloaddition reaction sodium azide copper chloride reagent, triazole preparation, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Electric Literature of 5301-96-2

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

On November 15, 2019, Shu, Wen-Ming; Zhang, Xun-Fang; Zhang, Xiang-Xiang; Li, Min; Wang, An-Jing; Wu, An-Xin published an article.Related Products of 5301-96-2 The title of the article was Metal-Free Cascade [4+1] Cyclization Access to 4-Aryl-NH-1,2,3-Triazoles from N-Tosylhydrazones and Sodium Azide. And the article contained the following:

A mol. iodine mediated coupling cyclization reaction for the synthesis of 4-aryl-NH-1,2,3-triazoles I (R1 = C6H5, 2-CH3C6H4, 3-CH3OC6H4, etc.; R2 = H, CH3, C6H5) has been developed from N-tosylhydrazones and sodium azide. This metal-free cascade [4+1] cyclization reaction could rapidly synthesize valuable compounds via a sequential C-N and N-N bond formation. Mechanistic studies demostrate that the nitrogen-atoms of the 1,2,3-triazoles are not entirely from sodium azide. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Related Products of 5301-96-2

The Article related to aryl triazole preparation metal free, tosylhydrazone sodium azide mol iodine cyclization, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Related Products of 5301-96-2

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Hui, Rongrong; Zhao, Mina; Chen, Ming; Ren, Zhihui; Guan, Zhenghui published an article in 2017, the title of the article was One-Pot Synthesis of 4-Aryl-NH-1,2,3-Triazoles through Three-Component Reaction of Aldehydes, Nitroalkanes and NaN3.Synthetic Route of 5301-96-2 And the article contains the following content:

A one-pot three-component reaction of aldehydes, nitroalkanes and NaN3 for the synthesis of NH-1,2,3-triazoles such as I [R1 = Ph, 2-furyl, 3-indolyl, etc.; R2 = H, Me, Et, CO2Et] was developed. The reaction provided a safe, efficient and step-economic approach for the synthesis of various NH-1,2,3-triazoles in good to excellent yields. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Synthetic Route of 5301-96-2

The Article related to triazole preparation, aryl aldehyde nitro alkane sodium azide three component condensation, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Synthetic Route of 5301-96-2

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics