Month: February 2024

Pore Wall-Functionalized Luminescent Cd(II) Framework for Selective CO₂ Adsorption, Highly Specific 2,4,6-Trinitrophenol Detection, and Colorimetric Sensing of Cu²⁺ Ions was written by Senthilkumar, S.;Goswami, Ranadip;Smith, Vincent J.;Bajaj, Hari C.;Neogi, Subhadip. And the article was included in ACS Sustainable Chemistry & Engineering in 2018.COA of Formula: C9H7N3O2 This article mentions the following:

Astute combination of basic functionality and luminescence property can pursue multifunctional metal-organic frameworks (MOFs) with assorted applications such as selective CO₂ adsorption, specific detection of explosive nitro compounds, and toxic metal ion sensing. The bifunctional ligand 4-(4-carboxyphenyl)-1,2,4-triazole (HL) is used to build the framework [Cd(L)₂]璺?DMF)_0.92 (1) (L = L^-1, DMF = N,N’-dimethylformamide), having a free N atom decorated porous channel. The solvothermal synthesis is extended to produce three isoskeletal frameworks in diverse solvents, where pore size maximizes in 2 by employing N,N’-diethylformamide solvent. The activated framework [Cd(L)₂] exhibits strong CO₂ affinity with good CO₂/N₂ selectivity, and shows min. CO₂ loss during five adsorption-desorption cycles. Sensing studies for nitro-aromatic compounds in DMF reveal highly specific detection of 2,4,6-trinitophenol (TNP) with remarkable quenching (K_SV = 9.3 鑴?10⁴ M^-1) and low limit of detection (LOD: 0.3 ppm). The quenching mechanism is ascribed to the combined existence of static and dynamic quenching plus resonance energy transfer. The activated framework further shows highly selective luminescent detection of Cu²⁺ ions with a quenching constant of 4.4 鑴?10³ M^-1 and very low LOD of 3.9 ppm. The detection of Cu²⁺ ions accompanies a visible color change in solution and solid phase, which validates the present system as a potential colorimetric Cu²⁺ sensor. Of note is that bifunctional sensor shows excellent reusability toward TNP and Cu²⁺ detection. Overall, selective and multicycle CO₂ adsorption, together with efficient sensing of both TNP and Cu²⁺ ion, manifest this pore-functionalized MOF as a versatile material for sustainability. In the experiment, the researchers used many compounds, for example, 4-(4H-1,2,4-Triazol-4-yl)benzoic acid (cas: 157069-48-2COA of Formula: C9H7N3O2).

4-(4H-1,2,4-Triazol-4-yl)benzoic acid (cas: 157069-48-2) belongs to triazole derivatives. Triazoles exhibit substantial isomerism, depending on the positioning of the nitrogen atoms within the ring. Triazoles are compounds with a vast spectrum of applications, varying from materials (polymers), agricultural chemicals, pharmaceuticals, photoactive chemicals and dyes.COA of Formula: C9H7N3O2

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Expanding Reactivity in DNA-Encoded Library Synthesis via Reversible Binding of DNA to an Inert Quaternary Ammonium Support was written by Flood, Dillon T.;Asai, Shota;Zhang, Xuejing;Wang, Jie;Yoon, Leonard;Adams, Zoe C.;Dillingham, Blythe C.;Sanchez, Brittany B.;Vantourout, Julien C.;Flanagan, Mark E.;Piotrowski, David W.;Richardson, Paul;Green, Samantha A.;Shenvi, Ryan A.;Chen, Jason S.;Baran, Phil S.;Dawson, Philip E.. And the article was included in Journal of the American Chemical Society in 2019.Category: triazoles This article mentions the following:

DNA Encoded Libraries have proven immensely powerful tools for lead identification. The ability to screen billions of compounds at once has spurred increasing interest in DEL development and utilization. Although DEL provides access to libraries of unprecedented size and diversity, the idiosyncratic and hydrophilic nature of the DNA tag severely limits the scope of applicable chemistries. It is known that biomacromols. can be reversibly, noncovalently adsorbed and eluted from solid supports, and this phenomenon has been utilized to perform synthetic modification of biomols. in a strategy we have described as reversible adsorption to solid support (RASS). Herein, we present the adaptation of RASS for a DEL setting, which allows reactions to be performed in organic solvents at near anhydrous conditions opening previously inaccessible chem. reactivities to DEL. The RASS approach enabled the rapid development of C(sp²)-C(sp³) decarboxylative cross-couplings with broad substrate scope, an electrochem. amination (the first electrochem. synthetic transformation performed in a DEL context), and improved reductive amination conditions. The utility of these reactions was demonstrated through a DEL-rehearsal in which all newly developed chemistries were orchestrated to afford a compound rich in diverse skeletal linkages. We believe that RASS will offer expedient access to new DEL reactivities, expanded chem. space, and ultimately more drug-like libraries. In the experiment, the researchers used many compounds, for example, 1H-Benzo[d][1,2,3]triazol-1-amine (cas: 1614-12-6Category: triazoles).

1H-Benzo[d][1,2,3]triazol-1-amine (cas: 1614-12-6) belongs to triazole derivatives. The triazole ring is a relatively stable functional group, and the triazole bond can be used for a variety of applications, such as replacing the phosphate backbone of DNA.Triazole heterocyclic structures are found to form many weak nonbond interactions with the receptors and enzymes in biological systems.Category: triazoles

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics