Ethyl 1H-1,2,3-triazole-5-carboxylate (cas: 40594-98-7) belongs to triazole derivatives. The many free lone pairs in triazoles make them useful as coordination compounds, although not typically as haptic ligands. The presence of the three nitrogen atoms in triazole structures afforded opportunities for a plethora of structural modification with the generation of novel therapeutically potential agents, which is different from other heterocyclic compounds.Recommanded Product: 40594-98-7
Syntheses of D-arabinofuranosyl and 2′-deoxy-D-ribofuranosyl 1,2,3-triazolecarboxamides was written by Makabe, Osamu;Suzuki, Hiroshi;Umezawa, Sumio. And the article was included in Bulletin of the Chemical Society of Japan in 1977.Recommanded Product: 40594-98-7 This article mentions the following:
Several D-arabino- and 2′-deoxy-D-ribonucleosides of 1,2,3-triazolecarboxamides were synthesized by 2 methods, one involving acid-catalyzed fusion reactions of 1-O-acetyl-2,3,5-tri-O-benzyl-D-arabinofuranose or 1-O-acetyl-3,5-di-O-(p-nitrobenzoyl)-D-2-deoxyribofuranose with Et 1,2,3-triazole-4-carboxylate (I), and the other by glycosylation of the trimethylsilyl derivative of I with 2,3,5-tri-O-benzyl-D-arabinofuranosyl chloride or 3,5-di-O-(p-toluoyl)-D-2-deoxyribofuranosyl chloride. Evidence for the N-glycosylation sites (1 or 2 of triazole) and anomeric configurations of the resulting nucleosides is presented. Of the compounds prepared nucleosides II (R = H, OH) showed antiviral and cytotoxic activities (no data). In the experiment, the researchers used many compounds, for example, Ethyl 1H-1,2,3-triazole-5-carboxylate (cas: 40594-98-7Recommanded Product: 40594-98-7).
Ethyl 1H-1,2,3-triazole-5-carboxylate (cas: 40594-98-7) belongs to triazole derivatives. The many free lone pairs in triazoles make them useful as coordination compounds, although not typically as haptic ligands. The presence of the three nitrogen atoms in triazole structures afforded opportunities for a plethora of structural modification with the generation of novel therapeutically potential agents, which is different from other heterocyclic compounds.Recommanded Product: 40594-98-7
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics