107534-96-3, A common heterocyclic compound, 107534-96-3, name is 3-((1H-1,2,4-Triazol-1-yl)methyl)-1-(4-chlorophenyl)-4,4-dimethylpentan-3-ol, molecular formula is C16H22ClN3O, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
A portion of cis-[PtCl2(DMSO)2] (0.53 g, 1.26 mmol) placed into a pear-shaped flask of 100 mL in volume was dissolved in chloroform (20 mL) under stirring on a water bath (40C). To the resulting solution, reagent L (0.89 g, 2.89 mmol) was added. The formed light-yellow transparent solution was boiled on a water bath for 19 h under reflux and magnetically stirring and then transferred into a 150-mL beaker and evaporated one-half. Complex I was precipitated from the solution cooled to room temperature with hexane. The mixture of the precipitate and the mother solution was cooled to 10C, the solution was then decanted, and hexane (100 mL) was added to the precipitate, thereupon the mixture was allowed to stand at -10C for 15 h. The precipitate was twice washed with hexane, reprecipitated with hexane from a chloroform solution, filtered out, washed with hexane, and dried in air. The yield was 62%.
The synthetic route of 107534-96-3 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Khisamutdinov; Anpilogova; Shitikova; Murinov, Yu. I.; Russian Journal of Inorganic Chemistry; vol. 61; 12; (2016); p. 1530 – 1537; Zh. Neorg. Khim.; vol. 61; 12; (2016); p. 1591 – 1598,8;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics