Synthetic Route of 16227-12-6, The chemical industry reduces the impact on the environment during synthesis 16227-12-6, name is 4-Phenyl-4H-1,2,4-triazole, I believe this compound will play a more active role in future production and life.
EXAMPLE 128 4-phenyl-1-(hept-1-yl)triazolium bromide 0.15 g (0.001 mol) 4-phenyltriazole 1 and 0.47 ml (0535 g, 0.003 mol) 1-bromoheptane 2 are combined in a pressure tube. The mixture is stirred for 12 h at 110 C. Subsequently, it is cooled down to room temperature. The precipitated solid is taken up in a 1:1 mixture of THF and petroleum ether, is filtered off, and washed with diethylether. M 324.26 C15H22N3Br Yield: 0.306 (94%) 1H-NMR DM-230 (300 MHz/DMSO): (ppm)=0.88 (t, 3H, 13-H); 1.37 (m, 8H, 9/10/11/12H); 1.96 (q, 2H, 8-H); 4.44 (t, 2H, 7-H); 7.69 (m, 3H, 5/5’/6H); 7.85 (d, 2H, 4/4′-H); 9.81 (s, 1H, 2-H); 10.85 (s, 1H, 1-H) 13C-NMR DM-230 (75.475 MHz/DMSO):
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Phenyl-4H-1,2,4-triazole, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; TECHNISCHE UNIVERSITAET DRESDEN; US2011/105761; (2011); A1;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics