Some common heterocyclic compound, 27996-86-7, name is 4-[1,2,4]Triazol-1-yl-benzaldehyde, molecular formula is C9H7N3O, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Formula: C9H7N3O
Weigh 1.73 g (10 mmol) of 1,2,4-triazole benzaldehyde, 4.28 g (10 mmol) of rhodamine hydrazine was dissolved in 20 mL of ethanol, and added to a 100 mL three-necked flask equipped with a thermometer and a stirring apparatus. To the above mixed solution, 0.40 g (7 mmol) of glacial acetic acid was added, and the mixture was refluxed under constant stirring at 80 C for 5 h, cooled to room temperature, and a white solid was precipitated, washed with cold ethanol and dried under vacuum at 50 C for 8 h to obtain a final product compound. (Triazolyl benzaldehyde, rhodamine hydrazine, Schiff base).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 27996-86-7, its application will become more common.
Reference:
Patent; Qilu University of Technology; Duan Hongdong; Zhong Wenxia; Wang Lizhen; (12 pag.)CN109761992; (2019); A;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics