Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 288-88-0, name is 1H-1,2,4-Triazole, A new synthetic method of this compound is introduced below., COA of Formula: C2H3N3
In 250ml three bottles,23.8 g of 2-tert-butyl-2- (4-chlorophenethyl) oxirane was added,2.0 g of potassium hydroxide and 800 g of PEG were added,And 8.0 g of 1,2,4-triazole was added,Temperature and control the temperature 130 ,Reaction for 7 hours,Stop the reaction.The filter mother liquor in Example 6 was added and the temperature was adjusted to 30 C for 3 hours and evacuated.The filter cake was dried to obtain 29.1 g of tebuconazole (white solid)Content of 98.1%,Yield 94.0%.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Yancheng Glorious Chemical Co., Ltd.; Dong Jiansheng; Guo Jianfa; Lu Chunhua; Wang Zhengrong; (7 pag.)CN106588791; (2017); A;,
1,2,3-Triazole – Wikipedia,
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