Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 15294-81-2, name is 4,5-Dibromo-1H-1,2,3-triazole, A new synthetic method of this compound is introduced below., Recommanded Product: 15294-81-2
EXAMPLE 4 1(2 or 3)-N,N-Diethylcarbamyl-4,5-dibromo-1H-1,2,3-triazole STR13 To a suspension of 213 milligrams (mg) (8.89 mmoles) of sodium hydride in 20 ml of anhydrous tetrahydrofuran was added 2 g (8.89 mmoles) of 4,5-dibromo-1H-1,2,3-triazole. The resulting suspension was cooled to 0¡ã C. and 1.2 g (8.89 moles) of N,N-diethylcarbamoyl chloride was added by drop. The reaction mixture was heated to reflux overnight and the precipitated sodium chloride was removed by filtration. Concentration of the filtrate in vacuo gave 2.4 g (82percent) of 1(2 or 3)-N,N-diethylcarbamyl-4,5-dibromo-1H-1,2,3-triazole as a yellow oil. The structure was confirmed by n.m.r. and I.R.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Stauffer Chemical Company; US4596596; (1986); A;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics