Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1455-77-2, name is 3,5-Diamino-1,2,4-triazole, This compound has unique chemical properties. The synthetic route is as follows., HPLC of Formula: C2H5N5
Example 142-Amino-5-cyclopropyl-6- [(3,4-dichlorophenyl)methyl] -4H- [ 1 ,2,4] triazolo [5,1- b] pyrimidin-7-oneEthyl 3-cyclopropyl-2-[(3,4-dichlorophenyl)methyl]-3-oxo-propanoate (200 mg, 634.5 mmol, Method II) and lH-l,2,4-triazole-3,5-diamine (57.2 mg, 577 mmol) were added to tri-n-butylamine (228 mu) and the resulting mixture stirred at 160 ¡ãC for 48 h. The mixture was evaporated and the residue recrystallised from isopropanol to give the title compound (43 mg, 21percent) as a white solid.1H NMR (400.13 MHz, DMSO-d6) delta 0.90-1.05 (4H, m), 2.05-2.17 (1H, m), 4.00 (2H, s), 6.25 (2H, br s), 7.28 (1H, d), 7.52 (2H, d), 12.20 (1H, br s); m/z (ES) (M+H)+ = 350.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 1455-77-2.
Reference:
Patent; ASTRAZENECA AB; ASTRAZENECA UK LIMITED; BENGTSSON, Boel, Ase; BLACKABY, Wesley; CUMMING, John; FAULL, Alan, Wellington; LARSSON, Joakim; NASH, Ian, Alun; OLDHAM, Keith; PAPE, Andrew; WO2011/114148; (2011); A1;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics