In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 1455-77-2 as follows. category: Triazoles
1H-1,2,4-Triazole-3,5-diamine (12.4 g, 0.125 mol) was dissolved in AcOH (50 ml), and diethyl 2-(ethoxymethylene)malonate (32.5 g, 0.15 mol) was added. The solution was refluxed overnight, then cooled, filtered, and dried to give Key Intermediate VI (22 g, 79percent) as a white solid.
According to the analysis of related databases, 1455-77-2, the application of this compound in the production field has become more and more popular.
Reference:
Patent; WOLKERSTORFER, Andrea; Szolar, Oliver; Handler, Norbert; Cusack, Stephen; Sauvaitre, Thibault; Simon, Celine; Morice, Christophe; Giethlen, Bruno; Langer, Thierry; Smith, Mark; So, Sung-Sau; Classen-Houben, Dirk; Buschmann, Helmut; US2013/317021; (2013); A1;,
1,2,3-Triazole – Wikipedia,
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