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Electric Literature of 60166-43-0, New Advances in Chemical Research in 2021.In classical electrochemical theory, both the electron transfer rate and the adsorption of reactants at the electrode control the electrochemical reaction. 60166-43-0, name is 1,4-Dimethyl-1H-1,2,3-triazole, molecular formula is C4H7N3, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, below Introduce a new synthetic route.

In a 75 mL pressure vessel equipped with a magnetic stirring bar was added (75% purity, yellow foam as the title compound. NMR (500MHz, DMSO-c e) delta 8.71 – 8.62 (m, 2H), 8.21 (t, J=7.3 Hz, 1H), 7.46 (d, J=8.1 Hz, 1H), 7.41 – 7.24 (m, 2H), 7.12 (t, J=9.4 Hz, 1H), 6.18 (br. s., 1H), 4.01 (br. s., 3H), 3.93 – 3.82 (m, 2H), 3.74 (d, J=9.9 Hz, 1H), 3.53 (d, J=8.8 Hz, 1H), 3.49 – 3.36 (m, 1H), 3.30 – 3.12 (m, 1H), 2.29 (s, 3H), 1.66 (d, J=1 1.7 Hz, 1H), 1.53 – 1.39 (m, 1H), 1.39 – 1.26 (m, 1H), 0.96 (d, J=12.5 Hz, 1H). LC/MS (M+H) = 491.4; HPLC conditions: Rt = 3.30 min (Phenomenex LUNA C 18 2 x 50 mm (4 min grad) eluting with 5-95% aq ACN containing lOmM NH4OAC, 0.8 mL/min, monitoring at 254 nm); Temperature: 40C).

The potential utility of systematic synthetic strategy will be applicable to efficient generations of chemical libraries of compounds to find ‘hit’ molecules.Read on for other articles about 1,4-Dimethyl-1H-1,2,3-triazole, hurry up and to see.

Reference:
Patent; BRISTOL-MYERS SQUIBB COMPANY; NORRIS, Derek J.; VACCARO, Wayne; DEBENEDETTO, Mikkel V.; DEGNAN, Andrew P.; DELUCCA, George V.; DESKUS, Jeffrey A.; HAN, Wen-Ching; KUMI, Godwin Kwame; SCHMITZ, William D.; STARRETT, John E., JR.; HILL, Matthew D.; HUANG, Hong; (563 pag.)WO2016/183118; (2016); A1;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics