Related Products of 956317-36-5, New Advances in Chemical Research in 2021. Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 956317-36-5, name is 5-Methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid, molecular formula is C10H9N3O2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, below Introduce a new synthetic route.
Step 2) Synthesis of 5-methyl-2- (2H-1, 2, 3-triazol-2-yl) benzoyl chlorideTo a solution of 5-methyl-2- (2H-1, 2, 3-triazol-2-yl) benzoic acid (2.03 g, 10 mmol) in anhydrous DCM (20 mL) were added sulfoxide chloride (15 mL, 206 mmol) and pyridine (0.15 mL, 2 mmol) slowly. The reaction was heated to reflux for 3 hours, and then cooled. The solvent was removed in vacuo to give a product, which was used directly in the next step.
Therefore, this conceptually novel strategy might open impressive avenues to establish green and sustainable chemistry platforms.In my other articles, you can also check out more blogs about 5-Methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid.
Reference:
Patent; SUNSHINE LAKE PHARMA CO., LTD.; ZHANG, Yingjun; JIN, Chuanfei; ZHANG, Ji; (90 pag.)WO2017/88759; (2017); A1;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics