HPLC of Formula: C2H4N4. Recently I am researching about OXIDATIVE STRESS; INORGANIC NANOPARTICLES; 1-CYS PEROXIREDOXIN; ANTIOXIDANT ENZYMES; FREE-RADICALS; CATALASE; 3-AMINO-1-2-4-TRIAZOLE; NANOMATERIALS; GLUTATHIONE; GENERATION, Saw an article supported by the Department of Science and Technology, New DelhiDepartment of Science & Technology (India); Department of Science and Technology.Science and Engineering Research Board (SERB) [ILS/SERB/2015-16/01]; Ahmedabad University [AU/SG/SAS/DBLS/17-18/03]; Centre for Nanotechnology Research and Applications (CENTRA) by The Gujarat Institute for Chemical Technology (GICT). Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Shah, J; Pandya, A; Goyal, P; Misra, SK; Singh, S. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine
Inorganic nanomaterials have gathered significant attention due to their biological enzyme-like catalytic activities, which are currently being utilized to display excellent biomedical applications. Among these, inorganic nanomaterials exhibiting catalase enzyme-like properties are of particular interest because they can impart protection to mammalian cells from cellular hydrogen peroxide (H2O2) and other free radicals. In this study, we have investigated the utility of bovine serum albumin (BSA) coated magnesium nanopartides (BSA-MgNPs) with respect to the protection of mammalian hepatic cells with depleted cellular catalase enzyme. We observed that BSA-MgNPs lead to the rapid breakdown of H2O2 and therefore protect mammalian cells exposed to 3-amino-1,2,4-triazole (3-AT), an irreversible catalase enzyme inhibitor. Results revealed that 3-AT induces oxidative stress by challenging the glutathione (GSH) and catalase enzyme, thus altering the cellular redox balance, which leads to the formation of reactive oxygen species (ROS) in human hepatocytes (WRL-68). Results showed that BSA-MgNPs impart protection to the catalase depleted hepatic cells. Expression analysis showed that BSA-MgNPs favorably modulate cellular antioxidant proteins/ enzymes and genes such as catalase, thioredoxin reductase (TrxR), peroxiredoxin 6 (Prx6), and Hsp 70 (heat shock protein). These results conclude that BSA-MgNPs impart protection to WRL-68 cells from acatalasia to display better cell survival as well as a remarkable decrease in the intracellular ROS levels.
HPLC of Formula: C2H4N4. Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.
Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics