《ZINClick v.18: Expanding Chemical Space of 1,2,3-Triazoles》 was written by Levre, Doriana; Arcisto, Chiara; Mercalli, Valentina; Massarotti, Alberto. Formula: C2H3N3This research focused onZINClick database triazole alkyne azide. The article conveys some information:
In the last years, we have investigated the click-chem. space covered by mols. containing the triazole ring and generated a database of 1,2,3-triazoles called ZINClick, starting from literature-reported alkynes and azides synthesizable in no more than three synthetic steps from com. available products. This combinatorial database contains millions of 1,4-disubstituted 1,2,3-triazoles that are easily synthesizable. The library is regularly updated and can be freely downloaded from http://www.ZINClick.organic In this communication, the new implementation of ZINClick will be discussed as well as our new strategy for clustering the chem. space covered by 1,4-disubstituted 1,2,3-triazoles around their availability: from direct purchase to different degrees of synthetic feasibility of the compounds In the part of experimental materials, we found many familiar compounds, such as 1H-1,2,3-Triazole(cas: 288-36-8Formula: C2H3N3)
1H-1,2,3-Triazole(cas: 288-36-8) belongs to triazoles. Triazoles are an important group of nitrogen-containing five-membered heterocyclic scaffolds. Triazoles are core structures of several drugs and pharmaceutical agents. Triazole derivatives possess antimicrobial, antiparasitic, antidiabetic, analgesic, and anti-inflammatory properties Formula: C2H3N3
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics