In 2016,Zeng, Vicky Ziman; Su, Haibin; Li, Tianhu published 《Computation-guided improved one-pot synthesis of macrocyclic cation-binding aromatic pyridone pentamers》.Organic & Biomolecular Chemistry published the findings.Computed Properties of C12H22F6N6OP2 The information in the text is summarized as follows:
By using polar DMF to relax the H-bonded rigid backbone and to lower the energetic penalty associated with the sterically-crowded environment, the yields for BOP-mediated 1-pot synthesis of pentameric macrocycles can be improved from 10-25% as obtained in CH2Cl2 to 13-47% when 15% DMF in CH2Cl2 was used as the reaction medium. In the experimental materials used by the author, we found ((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tris(dimethylamino)phosphonium hexafluorophosphate(V)(cas: 56602-33-6Computed Properties of C12H22F6N6OP2)
((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tris(dimethylamino)phosphonium hexafluorophosphate(V)(cas: 56602-33-6) is a peptide coupling reagent. Can be used in the preparation of phenyl esters of amino acids which have been shown to be valuable as blocked derivatives of amino acids in the field of peptide synthesis.Computed Properties of C12H22F6N6OP2
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics