Topchiy, Maxim A.’s team published research in ChemistrySelect in 2019 | CAS: 510758-28-8

Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8) can stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.Application In Synthesis of Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)aminePolytriazolylamines were synthesized by the copper(I)-catalyzed ligation of azides and alkynes.

In 2019,ChemistrySelect included an article by Topchiy, Maxim A.; Ageshina, Alexandra A.; Chesnokov, Gleb A.; Sterligov, Grigorii K.; Rzhevskiy, Sergey A.; Gribanov, Pavel S.; Osipov, Sergey N.; Nechaev, Mikhail S.; Asachenko, Andrey F.. Application In Synthesis of Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine. The article was titled 《Alkynyl- or Azido-Functionalized 1,2,3-Triazoles: Selective MonoCuAAC Promoted by Physical Factors》. The information in the text is summarized as follows:

In this present work, the possibility of selectivity control for mono addition in the copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction of sym. diazides or diacetylenes in equimolar amounts based on phys. rather than chem. factors was proposed and investigated. Single cycloaddition in the CuAAC reaction of sym. diazides or diynes could be achieved by (a) precipitation of the monoaddn. product, from nonpolar solvent heptane and (b) the reaction halt after formation of monoaddn. product due to increase of the viscosity in solvent-free procedure. Thus, two new green one-step methods for the synthesis of alkynyl- or azido-functionalized 1,2,3-triazoles I [R = n-Pr, SiMe3, Ph, etc.; R1 = CH2CO2Et, Ph, Bn, etc.] were devised. By using these methods 17 compounds were obtained with good to excellent yields. In addition to this study using Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine, there are many other studies that have used Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8Application In Synthesis of Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine) was used in this study.

Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8) can stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.Application In Synthesis of Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)aminePolytriazolylamines were synthesized by the copper(I)-catalyzed ligation of azides and alkynes.

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics