Holzer, Wolfgang published an article in Tetrahedron. The title of the article was 《Spectral and structural assignments with various N-substituted 1,2,4-triazoles: NOE difference spectroscopy as a powerful tool》.Computed Properties of C9H8N4O4S The author mentioned the following in the article:
The unambiguous discrimination between signals due to H-3 and H-5 in various 1-substituted 1H-1,2,4-triazoles as well as the differentiation between isomeric 1,3-, 1,5- and 3,4-disubstituted 1,2,4-triazoles by means of NOE difference spectroscopy is described. The assignments based on NOE difference experiments are shown to agree with those resting on triazole 13C,1H spin-coupling constants The experimental part of the paper was very detailed, including the reaction process of 3-Nitro-1-tosyl-1H-1,2,4-triazole(cas: 77451-51-5Computed Properties of C9H8N4O4S)
3-Nitro-1-tosyl-1H-1,2,4-triazole(cas: 77451-51-5) belongs to triazoles. Triazoles are an important group of nitrogen-containing five-membered heterocyclic scaffolds. Triazoles are core structures of several drugs and pharmaceutical agents. Triazole derivatives possess antimicrobial, antiparasitic, antidiabetic, analgesic, and anti-inflammatory properties Computed Properties of C9H8N4O4S
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics