On January 19, 2018, Bhagat, Ujjawal Kumar; Peddinti, Rama Krishna published an article.Name: 4-(p-Tolyl)-1H-1,2,3-triazole The title of the article was Asymmetric Organocatalytic Approach to 2,4-Disubstituted 1,2,3-Triazoles by N2-Selective Aza-Michael Addition. And the article contained the following:
Cycloalkenones (2-cyclohexen-1-one, 4,4-dimethyl-2-cyclohexen-1-one, 2-cyclopenten-1-one) underwent regio- and enantioselective aza-Michael reactions with aryl-1,2,3-triazoles in the presence of a nonracemic cinchonine-derived thiourea to yield nonracemic (oxocycloalkyl)aryltriazoles I [R = Ph, 3-MeOC6H4, 4-MeOC6H4, 4-MeC6H4, 4-i-PrC6H4, 2-ClC6H4, 4-ClC6H4, 2-O2NC6H4, 3-O2NC6H4, 2-BrC6H4, 4-BrC6H4, 2,5-(MeO)2C6H3, 3,4-(MeO)2C6H3, 2,3-Cl2C63, 2,4,5-(MeO)3C6H2, 2-methoxy-1-naphthyl; X = CH2, CMe2, bond] in 58-75% yields and in 44->99% ee (with 0-25% yields of regioisomeric products derived from N1-addition). The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Name: 4-(p-Tolyl)-1H-1,2,3-triazole
The Article related to oxocycloalkyl aryltriazole regioselective enantioselective preparation, regioselective enantioselective aza michael addition aryltriazole cycloalkenone cinchonine thiourea, cinchonine thiourea catalyst regioselective enantioselective michael addition aryltriazole cycloalkenone and other aspects.Name: 4-(p-Tolyl)-1H-1,2,3-triazole
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics