On May 18, 2017, Cha, Hyojin; Lee, Kyongkyu; Chi, Dae Yoon published an article.Electric Literature of 5301-96-2 The title of the article was Synthesis of N-unsubstituted 1,2,3-triazoles via aerobic oxidative N-dealkylation using copper(II) acetate. And the article contained the following:
A copper-catalyzed aerobic oxidative C-N bond cleavage reaction was developed for the synthesis of 4-substituted-NH-1,2,3-triazoles. Diverse β-ketotriazoles derivatives, which are the starting materials for the aerobic oxidative C-N bond cleavage reaction, were prepared from nine aryl and seven alkyl alkynes and α-azidoacetophenone by a copper(I)-catalyzed [3 + 2] cycloaddition reaction. The aerobic oxidation of α-(1,2,3-triazol-1-yl)acetophenones using a catalytic amount of copper(II) acetate in the presence oxygen under neutral conditions gave the title compounds in high yield [e.g., 1-phenacyl-4-phenyl-1H-1,2,3-triazole → 4-phenyl-1H-1,2,3-triazole (91%) in presence of Cu(OAc)2 and pyridine in PhCF3 under O2]. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Electric Literature of 5301-96-2
The Article related to copper catalyzed oxidative carbon nitrogen bond cleavage triazolylacetophenone, aerobic oxidative dealkylation triazolylacetophenone, triazole synthesis, azidoacetophenone cycloaddition aryl alkyl alkyne and other aspects.Electric Literature of 5301-96-2
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics