On August 7, 2008, Kalisiak, Jaroslaw; Sharpless, K. Barry; Fokin, Valery V. published an article.Product Details of 5301-96-2 The title of the article was Efficient Synthesis of 2-Substituted-1,2,3-triazoles. And the article contained the following:
In this three-component reaction, alkynes undergo a CuSO4-catalyzed cycloaddition with sodium azide and formaldehyde to yield 2-hydroxymethyl-2H-1,2,3-triazoles, which are useful intermediates that can be readily converted to polyfunctional mols. The hydroxymethyl group can also be removed, providing convenient access to NH-1,2,3-triazoles. The reaction is exptl. simple and readily scalable. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Product Details of 5301-96-2
The Article related to triazole preparation, copper catalyst cycloaddition alkyne azide formaldehyde, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Product Details of 5301-96-2
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics