Chen, Hai-Jiang published the artcileNew triazole derivatives containing substituted 1,2,3-triazole side chains: Design, synthesis and antifungal activity, Product Details of C12H13F2N3O4S, the publication is Chinese Chemical Letters (2017), 28(4), 913-918, database is CAplus.
A series of novel antifungal triazoles I (R = t-Bu, cyclopropyl, Ph) was designed and synthesized by reaction of azides with terminal alkynes. Synthesized compounds I were screened for their antifungal activity; results revealed that several target compounds showed good antifungal activity with a broad spectrum. In particular, compound I (R = cyclopropyl) was highly active against Candida albicans and Candida glabrata. Moreover, compound I (R = cyclopropyl) showed potent in vivo antifungal efficiency in the Caenorhabditis elegans-C. albicans infection model.
Chinese Chemical Letters published new progress about 86386-77-8. 86386-77-8 belongs to triazoles, auxiliary class Epoxides,Triazole,Fluoride,Salt,Sulfonic acid,Benzene, name is 1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole methanesulfonate, and the molecular formula is C12H13F2N3O4S, Product Details of C12H13F2N3O4S.
Referemce:
https://en.wikipedia.org/wiki/1,2,3-Triazole,
Triazoles – an overview | ScienceDirect Topics