An efficient method for the solid-phase synthesis of fluorescently labelled peptides was written by Fernandez-Carneado, Jimena;Giralt, Ernest. And the article was included in Tetrahedron Letters in 2004.HPLC of Formula: 156311-83-0 The following contents are mentioned in the article:
Fluorescent labeling of peptides is necessary in a wide range of cell biol. applications. In the last decade, the application of cell-penetrating mols. has been advanced by the use of peptides, which have proven efficient in aiding non-permeant mols. to cross the cell membrane. Currently, the development of new cell-penetrating peptides based on the design and synthesis of labeled peptide libraries is becoming critically important. We report an improved method for the solid-phase labeling of peptides, mediated by the activation of 5(6)-carboxyfluorescein with PyAOP/HOAt. This study involved multiple reactions and reactants, such as ((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0HPLC of Formula: 156311-83-0).
((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0) belongs to triazole derivatives. The triazole ring is a relatively stable functional group, and the triazole bond can be used for a variety of applications, such as replacing the phosphate backbone of DNA. The presence of the three nitrogen atoms in triazole structures afforded opportunities for a plethora of structural modification with the generation of novel therapeutically potential agents, which is different from other heterocyclic compounds.HPLC of Formula: 156311-83-0
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics