Synthesis of 1H-1,2,3-triazole under microwave irradiation was written by Xu, Wei-liang;Li, Yun-zheng;Zhang, Qing-shan;Zhu, He-sun. And the article was included in Jingxi Huagong in 2003.Computed Properties of C4H3N3O4 This article mentions the following:
Starting with benzotriazole, 1H-1,2,3-triazole was synthesized through two step reactions including oxidation by potassium permanganate and decarboxylation under microwave irradiation in overall yield of 64.7%. Compared with conventional method, in the decarboxylation reaction under microwave irradiation,the reaction time was reduced from 6 h to 6 min and the yield was enhanced from 65% to 97%. The product was corroborated by 1H NMR, 13C NMR, IR and MS. In the experiment, the researchers used many compounds, for example, 1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6Computed Properties of C4H3N3O4).
1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6) belongs to triazole derivatives. Triazoles exhibit substantial isomerism, depending on the positioning of the nitrogen atoms within the ring.Triazole heterocyclic structures are found to form many weak nonbond interactions with the receptors and enzymes in biological systems.Computed Properties of C4H3N3O4
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics