Holmberg, Rebecca J. et al. published their research in Chemical Communications (Cambridge, United Kingdom) in 2014 | CAS: 157069-48-2

4-(4H-1,2,4-Triazol-4-yl)benzoic acid (cas: 157069-48-2) belongs to triazole derivatives. Many triazoles are versatile, biologically active compounds commonly used as fungicides and plant retardants. 1,2,3-Triazoles are usually prepared following (3+2) cycloaddition protocols. A common technique for unsubstituted triazoles is the Huisgen azide-alkyne 1,3-dipolar cycloaddition: a azide and an alkyne react at high temperature to form a ring. However, the Huisgen strategy produces a mixture of isomers (typically 1,4- and 1,5-disubstituted) when used to produce substituted triazoles.Application In Synthesis of 4-(4H-1,2,4-Triazol-4-yl)benzoic acid

An unprecedented CoII cuboctahedron as the secondary building unit in a Co-based metal-organic framework was written by Holmberg, Rebecca J.;Kay, Marika;Korobkov, Ilia;Kadantsev, Eugene;Boyd, Peter G.;Aharen, Tomoko;Desgreniers, Serge;Woo, Tom K.;Murugesu, Muralee. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2014.Application In Synthesis of 4-(4H-1,2,4-Triazol-4-yl)benzoic acid This article mentions the following:

A cubic metal-organic framework, [CoII8(OH)6(cpt)6][CoCl4]2 (Hcpt = 4-(4′-carboxyphenyl)-1,2,4-triazole), with an unprecedented octanuclear secondary building unit (SBU) was isolated. The obtained SBU is composed of 8 CoII ions at each vertex, 6 μ4-OH groups at each face, and 12 cpt– ligands framing the metal core. The cuboctahedra arrange in a ubt framework topol., eliciting a highly sym. MOF structure. Magnetic measurements as well as DFT calculations on this crystalline MOF reveal intramol. antiferromagnetic coupling between CoII ions in the octanuclear SBU. In the experiment, the researchers used many compounds, for example, 4-(4H-1,2,4-Triazol-4-yl)benzoic acid (cas: 157069-48-2Application In Synthesis of 4-(4H-1,2,4-Triazol-4-yl)benzoic acid).

4-(4H-1,2,4-Triazol-4-yl)benzoic acid (cas: 157069-48-2) belongs to triazole derivatives. Many triazoles are versatile, biologically active compounds commonly used as fungicides and plant retardants. 1,2,3-Triazoles are usually prepared following (3+2) cycloaddition protocols. A common technique for unsubstituted triazoles is the Huisgen azide-alkyne 1,3-dipolar cycloaddition: a azide and an alkyne react at high temperature to form a ring. However, the Huisgen strategy produces a mixture of isomers (typically 1,4- and 1,5-disubstituted) when used to produce substituted triazoles.Application In Synthesis of 4-(4H-1,2,4-Triazol-4-yl)benzoic acid

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics