A new synthetic route of 1455-77-2

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 3,5-Diamino-1,2,4-triazole help many people in the next few years.

New discoveries in chemical research and development in 2021. The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. 1455-77-2, name is 3,5-Diamino-1,2,4-triazole belongs to triazoles compound, it is a common compound, a new synthetic route is introduced below. category: Triazoles

Added to three neck fever bottle 126mmol stearic acid, 60mmol3,5-diamino -1, 2, 4-three nitrogen […] 21g glycol solvent, under the protection of argon gas, heating 80 °C after melting, by adding 3mmol potassium hydroxide, wherein stearic acid: 3,5-diamino -1, 2, 4-triazole: potassium hydroxide mole ratio is 2.1: 1 : 0.05, glycol as the above-mentioned reactant of the total weight of the 50percent. Continued heating to 150 °C, reaction 12h rear, with 1percent sodium carbonate water solution, in order to remove unreacted stearic acid and the solvent is ethylene glycol, drying to obtain yellow solid containing heterocyclic stearic acid amide-based intermediate A.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 3,5-Diamino-1,2,4-triazole help many people in the next few years.

Reference:
Patent; China Petroleum & Chemical Corporation; Yu, Jianye; Lu, Minhui; Yuan, Ping; Yuan, Yufeng; (9 pag.)CN105693640; (2016); A;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics