A new synthetic route of 27996-86-7

The chemical industry reduces the impact on the environment during synthesis 4-[1,2,4]Triazol-1-yl-benzaldehyde. I believe this compound will play a more active role in future production and life.

Related Products of 27996-86-7, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 27996-86-7, name is 4-[1,2,4]Triazol-1-yl-benzaldehyde, This compound has unique chemical properties. The synthetic route is as follows.

To a solution of i-(3,5-dichlorophenyl)ethanone (0.5 g, 2.6 mmol) in ethanol (20 mE) was added 4-(iH-i,2, 4-triazol-i -yl)benzaldehyde (0.46 g, 2.65 mmol) and the reaction was cooled to 0C. Sodium hydroxide (0.22 g, 5.29 mmol) in water (10 mE) was then added and the reaction was allowed to stir for 2 hat 0 C. The reaction was extracted with EtOAc and the combined organic layers were dried over Na2504 and concentrated under reduced pressure to afford the title compound (0.149 g, 17%):); ESIMS mlz 430.05 ([M+H]) 344.08

The chemical industry reduces the impact on the environment during synthesis 4-[1,2,4]Triazol-1-yl-benzaldehyde. I believe this compound will play a more active role in future production and life.

Reference:
Patent; Dow AgroSciences LLC; Lo, William C.; Hunter, James E.; Watson, Gerald B.; Patny, Akshay; Iyer, Pravin S.; Boruwa, Joshodeep; US2014/171312; (2014); A1;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics