Electric Literature of 1455-77-2,Some common heterocyclic compound, 1455-77-2, name is 3,5-Diamino-1,2,4-triazole, molecular formula is C2H5N5, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
3,5-Diamino-1,2,4-triazole (2:40 g 24:2 mmol) was dissolved in 50 mL DMF at ambient temperature, and 10 mL (6 mmol) of a 0:6 M solution of dichlorotetrazine in acetonitrile was added via a dropping funnel. The solution was stirred for 2 h at ambient temperature. The product started to precipitate rather quickly. The suspension was heated to 120 ¡ãC for 16 h. After filtration the product was successively washed with large amounts of DMF, water and acetonitrile to gain 1:40 g (5:07 mmol, 85percent) of 8 as a brownish-red powder.? Elemental analysis (C6H8N14, 276.22) exp. (calcd.)in percent: C 26.25 (26.09), N 69.99 (70.99), H 2.90 (2.92).? DSC (5 C min1): T dec:: 370 ¡ãC (onset). ? 1H NMR([D6]DMSO, 80 ¡ãC, ppm): d =7.34 (2H, NH2), 5.66 (2H,NH2). ? 13C NMR ([D6]DMSO, 80 ¡ãC, ppm): d =162.5(1C), 155.5 (1C), 152.6 (1C). ? MS ((+)-DEI): m=z=276[M]+ (23), 99 [C2H5N5]+ (100), 124 C2N5H4-CN]+ (21). ?Raman: n (cm-1)=1931 (6), 1643 (4), 1622 (9), 1560 (2),1546 (12), 1498 (100), 1420 (15), 1368 (12), 1166 (17), 1058(4), 844 (45), 797 (2), 780 (29), 746 (3), 658 (2), 591 (2), 478(3), 415 (8), 372 (2). ? IR (25 C, ATR): n (cm-1)=3416(w), 3383 (w), 3272 (w), 3214 (w), 3131 (w, br), 1620 (s),1554 (m), 1474 (s), 1448 (vs), 1388 (m), 1331 (w), 1151 (m),1134 (m), 1083 (w), 1054 (m), 1028 (m), 956 (m), 828 (m),758 (m), 704 (m), 669 (m), 655 (vw). ? Density: r (g cm3):1.75. ? Sensitivity data: IS: > 40 J; FS: > 360 N; ESD: > 1 J.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 3,5-Diamino-1,2,4-triazole, its application will become more common.
Reference:
Article; Klapoetke, Thomas M.; Preimesser, Andreas; Stierstorfer, Joerg; Zeitschrift fur Naturforschung, B: Chemical Sciences; vol. 68; 12; (2013); p. 1310 – 1320;,
1,2,3-Triazole – Wikipedia,
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