Analyzing the synthesis route of 288-88-0

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1H-1,2,4-Triazole, other downstream synthetic routes, hurry up and to see.

Adding a certain compound to certain chemical reactions, such as: 288-88-0, name is 1H-1,2,4-Triazole, belongs to triazoles compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 288-88-0, name: 1H-1,2,4-Triazole

0.69 g (10 mmol) of 1,2,4-triazole, 2.07 g (15 mmol) of potassium carbonate, 1.49 g(12mmol) of p-fluorobenzaldehyde, and dissolved in 50 mL of N,N-dimethylformamide. It was placedina 100 mL three-neckedflaskequipped with a thermometer and a stirring device.The reaction was carried out under constant temperature stirring at 100 C for 16 h, cooled to room temperature, extracted, suction filtered, separated by column chromatography, washed with warm water, recrystallized from anhydrous ethanol, and dried under vacuum at 50 C for 8 h to obtain 1,2,4-triazole benzaldehyde.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1H-1,2,4-Triazole, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Qilu University of Technology; Duan Hongdong; Zhong Wenxia; (12 pag.)CN109867683; (2019); A;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics