Analyzing the synthesis route of C9H9N3O

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 103755-58-4.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 103755-58-4, name is (1-Phenyl-1H-1,2,3-triazol-4-yl)methanol, This compound has unique chemical properties. The synthetic route is as follows., Safety of (1-Phenyl-1H-1,2,3-triazol-4-yl)methanol

A solution of 8.75 g (0.05 mol) of (1-phenyl-1H-1,2,3-triazol-4-yl)methanol (11) in 100 mL of methylene chloride was added in one portion with thorough stirring to a suspension of 16.15 g (0.075 mol) of freshly prepared pyridinium chlorochromate (PCC) in 200 mL of anhydrous methylene chloride. The mixture was stirred for 90 min at room temperature, 200 mL of anhydrous diethyl ether was added, the solution was separated from the black precipitate by decanting, and the precipitate was washed with diethyl ether (2 ¡Á 50 mL). The combined extracts were filtered through 20 g of silica gel, the solvent was distilled off under reduced pressure, and the residue was recrys-tallized from carbon tetrachloride. Yield 6.75 g (78%). mp 96-97C. 1 H NMR spectrum (500 MHz, DMSO-d 6 ), delta, ppm: 7.57 t (1H, p-H, J = 7.2 Hz), 7.65 t (2H, m-H, J = 7.2 Hz), 8.03 d (2H, o-H, J = 7.2 Hz), 9.59 s (1H, 5-H), 10.24 s (1H, CHO). Mass spectrum: m/z 174 [M + H] + . Found, %: C 62.45; H 4.14; N 24.21. C 9 H 7 N 3 O. Calculated, %: C 62.42; H 4.07; N 24.27.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 103755-58-4.

Reference:
Article; Pokhodylo; Tupychak; Shyyka, O. Ya.; Obushak; Russian Journal of Organic Chemistry; vol. 55; 9; (2019); p. 1310 – 1321; Zh. Org. Khim.; vol. 55; 9; (2019); p. 1393 – 1405,13;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics