Authors Liu, XT; Xing, SS; Xu, YT; Chen, RQ; Lin, C; Guo, LQ in PERGAMON-ELSEVIER SCIENCE LTD published article about in [Liu, Xiaotao; Xing, Shanshan; Guo, Liangqia] Fuzhou Univ, Coll Chem, Fujian Prov Key Lab Anal & Detect Technol Food Sa, Minist Educ,Key Lab Analyt Sci Food Safety & Biol, Fuzhou 350116, Peoples R China; [Xu, Yuanteng; Lin, Chang] Fujian Med Univ, Affiliated Hosp 1, Dept Otorhinolaryngol, Fuzhou 350005, Peoples R China; [Chen, Ruiqing] Fujian Med Univ, Affiliated Hosp 1, Cent Lab, Fuzhou 350005, Peoples R China in 2021.0, Cited 40.0. Recommanded Product: 61-82-5. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5
Graphitic carbon nitride (g-C3N4) has been shown as a promising visible-light photosensitizer for photodynamic therapy (PDT) application. Nevertheless, its therapeutic efficiency is limited by the low efficiency of visible-light utilization. To overcome this issue, 3-amino-1,2,4-triazole-derived graphitic carbon nitride nanosheets (g-C3N5 NSs) are prepared for PDT application. The addition of nitrogen-rich triazole group into the g-C3N4 motif significantly makes the light absorption of g-C3N5 NSs red-shift with the band gap down to 1.95 eV, corresponding to a absorption edge at a wavelength of 636 nm. g-C3N5 NSs generate superoxide anion radicals (O-2(center dot-)) and singlet oxygen (O-1(2)) under the irradiation of a low-intensity white light emitting diode. Owing to the high efficiency of visible-light utilization, g-C3N5 NSs show about 9.5 fold photocatalytic activity of g-C3N4 NSs. In vitro anticancer studies based on the results of CCK-8 assay, Calcein-AM/PI cell-survival assay and photo-induced intracellular ROS level analysis in living HeLa cells demonstrate the potential of g-C3N5 NSs as a low-toxic and biocompatible high-efficient photosensitizer for PDT. (C) 2020 Elsevier B.V. All rights reserved.
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Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics