Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 2873-97-4, Name is N-(2-Methyl-4-oxopentan-2-yl)acrylamide, molecular formula is C9H15NO2, belongs to Triazoles compound. In a document, author is Fukumoto, Yoshiya, introduce the new discover, Product Details of 2873-97-4.
Iridium-Catalyzed Direct Amidation of Imidazoles at the C-2 Position with Isocyanates in the Presence of Hydrosilanes Leading to Imidazole-2-Carboxamides
Regioselective coupling reaction of N-substituted imidazoles with isocyanates in the presence of a stoichiometric amount of hydrosilanes catalyzed by Ir-4(CO)(12) to give imidazole-2-carboxamides is reported. Imidazoles bearing an (O-silyl)carboximidate group at the 2-position appear to be initially formed in the reaction; these are then hydrolyzed to the final products in situ. The addition of the hydrosilane was essential for the catalytic reaction to proceed. Substituents on the imidazole ring had no effect on the reaction, except for certain bulky substituents such as tBu and Ph groups at the 4-position. Triazoles such as 4-methyl-4H-1,2,4-triazole and 1-methyl-1H-1,2,4-triazole were also applicable to this C-H amidation, and the latter reaction proceeded regioselectively at the carbon atom between the sp(3) and sp(2) nitrogen atoms of the ring, and not between the two sp(2) nitrogen atoms.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 2873-97-4. Product Details of 2873-97-4.