Formula: C2H3N3In 2019 ,《1,2,3-Triazole-containing hybrids as leads in medicinal chemistry: A recent overview》 appeared in Bioorganic & Medicinal Chemistry. The author of the article were Bozorov, Khurshed; Zhao, Jiangyu; Aisa, Haji A.. The article conveys some information:
A review. The 1,2,3-triazole ring is a major pharmacophore system among nitrogen-containing heterocycles. These five-membered heterocyclic motifs with three nitrogen heteroatoms can be prepared easily using ‘click’ chem. with copper- or ruthenium-catalyzed azide-alkyne cycloaddition reactions. Recently, the ‘linker’ property of 1,2,3-triazoles was demonstrated, and a novel class of 1,2,3-triazole-containing hybrids and conjugates was synthesized and evaluated as lead compounds for diverse biol. targets. These lead compounds have been demonstrated as anticancer, antimicrobial, anti-tubercular, antiviral, antidiabetic, antimalarial, anti-leishmanial, and neuroprotective agents. The present review summarises advances in lead compounds of 1,2,3-triazole-containing hybrids, conjugates, and their related heterocycles in medicinal chem. published in 2018. This review will be useful to scientists in research fields of organic synthesis, medicinal chem., phytochem., and pharmacol. After reading the article, we found that the author used 1H-1,2,3-Triazole(cas: 288-36-8Formula: C2H3N3)
1H-1,2,3-Triazole(cas: 288-36-8) belongs to triazoles. Triazoles are an important group of nitrogen-containing five-membered heterocyclic scaffolds. Triazoles are core structures of several drugs and pharmaceutical agents. Triazole derivatives possess antimicrobial, antiparasitic, antidiabetic, analgesic, and anti-inflammatory properties Formula: C2H3N3
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics