Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 86404-63-9, is researched, SMILESS is FC1=CC=C(C(CN2N=CN=C2)=O)C(F)=C1, Molecular C10H7F2N3OJournal, Chromatographia called Direct resolution of a new antifungal agent, voriconazole (UK-109,496) and its potential impurities, by use of coupled achiral-chiral high-performance liquid chromatography, Author is Ferretti, R.; Gallinella, B.; La Torre, F.; Zanitti, L., the main research direction is voriconazole resolution HPLC; enantiomer separation voriconazole HPLC.HPLC of Formula: 86404-63-9.
Coupled achiral-chiral high-performance liquid chromatog. (HPLC) with an achiral amino-based column coupled with a chiral amylose-based column was used for qual. and quant. determination of the potential chiral and achiral impurities of voriconazole (UK-109,496), a new antifungal agent with two stereogenic centers. The effect of the organic mobile-phase modifier, ethanol, was studied. The assay response was linearly dependent on concentration over the range 1.2-40.4 μg for voriconazole and 2.5-104.0 ng for the impurities. The limit of detection was 2.5 ng for each analyte.
The article 《Direct resolution of a new antifungal agent, voriconazole (UK-109,496) and its potential impurities, by use of coupled achiral-chiral high-performance liquid chromatography》 also mentions many details about this compound(86404-63-9)HPLC of Formula: 86404-63-9, you can pay attention to it, because details determine success or failure
Reference:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics