Computed Properties of C2H4N4. In 2020.0 PLANT PHYSIOL published article about ABIOTIC STRESS; ARABIDOPSIS; SUMO; PROTEINS; DROUGHT; CONJUGATION; BINDING; TOLERANCE; PATHWAYS; IDENTIFY in [Wang, Feige; Shi, Yaqiao; Han, Danlu; Wu, Yuanyuan; Ye, Weixian; Yang, Huanling; Lai, Jianbin; Yang, Chengwei] South China Normal Univ, Sch Life Sci, Guangdong Prov Key Lab Biotechnol Plant Dev, Guangzhou 510631, Peoples R China; [Liu, Yiyang; Li, Guowei; Cui, Feng; Wan, Shubo] Shandong Acad Agr Sci, Biotechnol Res Ctr, Jinan 250100, Peoples R China; [Liu, Yiyang; Li, Guowei; Cui, Feng; Wan, Shubo] Shandong Prov Key Lab Crop Genet Improvement Ecol, Jinan 250100, Peoples R China in 2020.0, Cited 35.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.
Heat stress (HS) has serious effects on plant development, resulting in heavy agricultural losses. A critical transcription factor network is involved in plant adaptation to high temperature. DEHYDRATION RESPONSIVE ELEMENT-BINDING PROTEIN2A (DREB2A) is a key transcription factor that functions in plant thermotolerance. The DREB2A protein is unstable under normal temperature and is degraded by the 26S proteasome; however, the mechanism by which DREB2A protein stability dramatically increases in response to HS remains poorly understood. In this study, we found that the DREB2A protein of Arabidopsis (Arabidopsis thaliana) is stabilized under high temperature by the posttranslational modification SUMOylation. Biochemical data indicated that DREB2A is SUMOylated at K163, a conserved residue adjacent to the negative regulatory domain during HS. SUMOylation of DREB2A suppresses its interaction with BPM2, a ubiquitin ligase component, consequently increasing DREB2A protein stability under high temperature. In addition, analysis of plant heat tolerance and marker gene expression indicated that DREB2A SUMOylation is essential for its function in the HS response. Collectively, our data reveal a role for SUMOylation in the maintenance of DREB2A stability under high temperature, thus improving our understanding of the regulatory mechanisms underlying HS response in plant cells. SUMOylation increases the protein stability of DREB2A, a key transcription factor in the response to heat stress in plant cells.
Computed Properties of C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Wang, FG; Liu, YY; Shi, YQ; Han, DL; Wu, YY; Ye, WX; Yang, HL; Li, GW; Cui, F; Wan, SB; Lai, JB; Yang, CW or concate me.
Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics