In 2017,Castro, Vida; Noti, Christian; Chen, Wenqian; Cristau, Michele; Livignston, Andrew; Rodriguez, Hortensia; Albericio, Fernando published 《Novel Globular Polymeric Supports for Membrane-Enhanced Peptide Synthesis》.Macromolecules (Washington, DC, United States) published the findings.SDS of cas: 56602-33-6 The information in the text is summarized as follows:
Membrane-enhanced peptide synthesis (MEPS), a technique that combines liquid-phase peptide synthesis (LPPS) with organic solvent nanofiltration (OSN), has emerged as a new methodol. to tackle current challenges in solid-phase peptide synthesis (SPPS), the current strategy of choice for the preparation of peptides. This new technol. platform is scalable beyond kilogram scale, automatable, and compatible with established Fmoc chem., as it combines chem. in solution with expedient membrane purification Here we screened novel highly rejected soluble polymeric supports and studied their application for the preparation of a model peptide. Our findings make a significant contribution to the development of MEPS. In addition to this study using ((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tris(dimethylamino)phosphonium hexafluorophosphate(V), there are many other studies that have used ((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tris(dimethylamino)phosphonium hexafluorophosphate(V)(cas: 56602-33-6SDS of cas: 56602-33-6) was used in this study.
((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tris(dimethylamino)phosphonium hexafluorophosphate(V)(cas: 56602-33-6) is used as a reagent for peptide coupling, lactonization, selective esterification, amidation of alfa amino acids without racemization and synthesis of magnolamide for antioxidative activity and catalyst for 9-acridinecaroboxamide derivative. It acts as a substitute for (Benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) reagent.SDS of cas: 56602-33-6
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics