Category: 16227-12-6

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 16227-12-6, name is 4-Phenyl-4H-1,2,4-triazole, This compound has unique chemical properties. The synthetic route is as follows., HPLC of Formula: C8H7N3

EXAMPLE 130 4-phenyl-1-(undec-1-yl)triazolium bromide 0.15 g (0.001 mol) 4-phenyltriazole 1 and 0.486 g (0.003 mol) 1-bromoheptane 2 are combined in a pressure tube. The mixture is stirred for 12 h at 110 C. Subsequently, it is cooled down on room temperature. The precipitated solid is taken up in a 1:1 mixture of THF and petroleum ether, is filtered off, and washed with diethylether. M 380.37 C15H22N3Br Yield: 0.242 g (64%) 1H-NMR DM-230 (300 MHz/DMSO): (ppm)=0.88 (t, 3H, 13-H); 1.37 (m, 8H, 9/10/11/12H); 1.96 (q, 2H, 8-H); 4.44 (t, 2H, 7-H); 7.69 (m, 3H, 5/5’/6H); 7.85 (d, 2H, 4/4′-H); 9.81 (s, 1H, 2-H); 10.85 (s, 1H, 1-H) 13C-NMR DM-230 (75.475 MHz/DMSO):

According to the analysis of related databases, 16227-12-6, the application of this compound in the production field has become more and more popular.

Reference:
Patent; TECHNISCHE UNIVERSITAET DRESDEN; US2011/105761; (2011); A1;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Synthetic Route of 16227-12-6, The chemical industry reduces the impact on the environment during synthesis 16227-12-6, name is 4-Phenyl-4H-1,2,4-triazole, I believe this compound will play a more active role in future production and life.

EXAMPLE 128 4-phenyl-1-(hept-1-yl)triazolium bromide 0.15 g (0.001 mol) 4-phenyltriazole 1 and 0.47 ml (0535 g, 0.003 mol) 1-bromoheptane 2 are combined in a pressure tube. The mixture is stirred for 12 h at 110 C. Subsequently, it is cooled down to room temperature. The precipitated solid is taken up in a 1:1 mixture of THF and petroleum ether, is filtered off, and washed with diethylether. M 324.26 C15H22N3Br Yield: 0.306 (94%) 1H-NMR DM-230 (300 MHz/DMSO): (ppm)=0.88 (t, 3H, 13-H); 1.37 (m, 8H, 9/10/11/12H); 1.96 (q, 2H, 8-H); 4.44 (t, 2H, 7-H); 7.69 (m, 3H, 5/5’/6H); 7.85 (d, 2H, 4/4′-H); 9.81 (s, 1H, 2-H); 10.85 (s, 1H, 1-H) 13C-NMR DM-230 (75.475 MHz/DMSO):

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Phenyl-4H-1,2,4-triazole, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; TECHNISCHE UNIVERSITAET DRESDEN; US2011/105761; (2011); A1;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

16227-12-6, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 16227-12-6, name is 4-Phenyl-4H-1,2,4-triazole, A new synthetic method of this compound is introduced below.

EXAMPLE 129 4-phenyl-1-(hex-1-yl)triazolium bromide 0.15 g (0.001 mol) 4-phenyltriazole 1 and 0.42 ml (0.495 g, 0.003 mol) 1-bromohexane 2 are combined in a pressure tube. The mixture is stirred for 12 h at 110 C. Subsequently, it is cooled down to room temperature. The precipitated solid is taken up in a 1:1 mixture of THF and petroleum ether, is filtered off, and washed with diethylether. M 310.23 C14H20N3Br Yield: 0.254 g (82%) 1H-NMR DM-231 (300 MHz/DMSO): (ppm)=0.89 (t, 3H, 12-H); 1.33 (m, 6H, 9/10/11H): 1.96 (q, 2H, 8-H); 4.45 (t, 2H, 7-H); 7.69 (m, 3H, 5/5’/6H); 7.86 (d, 2H, 4/4′-H); 9.81 (s, 1H, 2-H); 10.88 (s, 1H, 1-H) 13C-NMR DM-231 (75.475 MHz/DMSO):

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Patent; TECHNISCHE UNIVERSITAET DRESDEN; US2011/105761; (2011); A1;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics