Category: 4546-95-6

Cao, Wenli et al. published their research in Molecules in 2021 | CAS: 4546-95-6

1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6) belongs to triazole derivatives. Among the nitrogen-containing heterocyclic compounds, triazoles emerge with superior pharmacological applications. Triazole growth retardants such as uniconazole and paclobutrazol have been known to inhibit the biosynthesis of gibberellins by blocking kaurene oxidase, an P450 enzymeApplication of 4546-95-6

4,5-Dicyano-1,2,3-Triazole-A Promising Precursor for a New Family of Energetic Compounds and Its Nitrogen-Rich Derivatives: Synthesis and Crystal Structures was written by Cao, Wenli;Qin, Jian;Zhang, Jianguo;Sinditskii, Valery P.. And the article was included in Molecules in 2021.Application of 4546-95-6 This article mentions the following:

The nitrogen-rich compounds and intermediates with structure of monocyclic, bicyclic, and fused rings based on 1,2,3-triazole were synthesized and prepared by using a promising precursor named 4,5-dicyano-1,2,3-triazole, which was obtained by the cyclization reaction of diaminomaleonitrile. Their structure and configurational integrity were assessed by Fourier transform-IR spectroscopy (FT-IR), mass spectrometry (MS), and elemental anal. (EA). Addnl., fourteen compounds were further confirmed by X-ray single crystal diffraction. Meanwhile, the phys. properties of four selected compounds including thermal stability, detonation parameters, and sensitivity were also estimated All these compounds could be considered to construct more abundant 1,2,3-triazole-based neutral energetic mols., salts, and complex compounds, which need to continue study in the future in the field of energetic materials. In the experiment, the researchers used many compounds, for example, 1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6Application of 4546-95-6).

1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6) belongs to triazole derivatives. Among the nitrogen-containing heterocyclic compounds, triazoles emerge with superior pharmacological applications. Triazole growth retardants such as uniconazole and paclobutrazol have been known to inhibit the biosynthesis of gibberellins by blocking kaurene oxidase, an P450 enzymeApplication of 4546-95-6

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Capitan, F. et al. published their research in Anales de Quimica (1968-1979) in 1973 | CAS: 4546-95-6

1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6) belongs to triazole derivatives. However, triazoles are also useful in bioorthogonal chemistry, because the large number of nitrogen atoms causes triazoles to react similar to azides. Due to the structural characteristics, both 1,2,3- and 1,2,4-triazoles are able to accommodate a broad range of substituents (electrophiles and nucleophiles) around the core structures and pave the way for the construction of diverse novel bioactive molecules.Application of 4546-95-6

The ir and uv spectra, and reactivity with inorganic ions, of 1,2,3-triazole-4,5-dicarboxylic acid was written by Capitan, F.;Salinas, F.;Alonso, E. J.. And the article was included in Anales de Quimica (1968-1979) in 1973.Application of 4546-95-6 This article mentions the following:

1,2,3-triazole-4,5-dicarboxylic acid was prepared according to the literature, and its ir and uv spectra was established. The acidity constants were determined from the influence of the pH on the uv spectrum. The reactivity against 45 inorganic ions was studied also. This substance possesses a high selective character, because it only reacts with the cations Ag(I), Pb(II), Hg2(II), Hg(II), Cu(II), Pd(II), Co(II), Cr(III), and Rh(III). The sensitivities of these reactions are low. In the experiment, the researchers used many compounds, for example, 1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6Application of 4546-95-6).

1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6) belongs to triazole derivatives. However, triazoles are also useful in bioorthogonal chemistry, because the large number of nitrogen atoms causes triazoles to react similar to azides. Due to the structural characteristics, both 1,2,3- and 1,2,4-triazoles are able to accommodate a broad range of substituents (electrophiles and nucleophiles) around the core structures and pave the way for the construction of diverse novel bioactive molecules.Application of 4546-95-6

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Yuan, Gang et al. published their research in Science China: Chemistry in 2010 | CAS: 4546-95-6

1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6) belongs to triazole derivatives. Triazoles exhibit substantial isomerism, depending on the positioning of the nitrogen atoms within the ring. Triazole growth retardants such as uniconazole and paclobutrazol have been known to inhibit the biosynthesis of gibberellins by blocking kaurene oxidase, an P450 enzymeElectric Literature of C4H3N3O4

Synthesis and characterization of two novel coordination polymers based on the rigid 1H-1,2,3-triazole-4,5-dicarboxylic acid ligand was written by Yuan, Gang;Shao, Kui Zhan;Du, Dong Ying;Wang, Xin Long;Su, Zhong Min. And the article was included in Science China: Chemistry in 2010.Electric Literature of C4H3N3O4 This article mentions the following:

Two novel three-dimensional (3-D) coordination polymers, [Pb(HTDA)]n(1) and [Co5(TDA)2(H2TDA)2(H2O)8]n (2) [H3TDA = 1H-1,2,3-triazole-4,5-dicarboxylic acid], were prepared by hydrothermal reactions and characterized by elemental anal., IR spectroscopy and single-crystal x-ray diffraction. Compound 1 is constructed from rod-shaped secondary building units (SBUs) and exhibits a 3-D network with (410·65)(410·63·82) topol. Compound 2 is built up from ligands bridging three different cobalt ions and exhibits a 3-D network with (4.82)3(4.82·103) topol. In addition, the thermal stabilities of the two compounds, the photoluminescence properties of compound 1 and the magnetic properties of compound 2 were studied. In the experiment, the researchers used many compounds, for example, 1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6Electric Literature of C4H3N3O4).

1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6) belongs to triazole derivatives. Triazoles exhibit substantial isomerism, depending on the positioning of the nitrogen atoms within the ring. Triazole growth retardants such as uniconazole and paclobutrazol have been known to inhibit the biosynthesis of gibberellins by blocking kaurene oxidase, an P450 enzymeElectric Literature of C4H3N3O4

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Wu, Jiali et al. published their research in Chemical Engineering Journal (Amsterdam, Netherlands) in 2020 | CAS: 4546-95-6

1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6) belongs to triazole derivatives. Many triazoles are versatile, biologically active compounds commonly used as fungicides and plant retardants. Triazole growth retardants such as uniconazole and paclobutrazol have been known to inhibit the biosynthesis of gibberellins by blocking kaurene oxidase, an P450 enzymeRecommanded Product: 1H-1,2,3-Triazole-4,5-dicarboxylic acid

Degradation of benzotriazole by DBD plasma and peroxymonosulfate: Mechanism, degradation pathway and potential toxicity was written by Wu, Jiali;Xiong, Qing;Liang, Jialiang;He, Qiang;Yang, Dongxu;Deng, Ruoyu;Chen, Yi. And the article was included in Chemical Engineering Journal (Amsterdam, Netherlands) in 2020.Recommanded Product: 1H-1,2,3-Triazole-4,5-dicarboxylic acid This article mentions the following:

Benzotriazole (BTA), a widely used chem. in domestic and industrial products, is bio-refractory and is an emerging contaminant in the aquatic environment. An approach to degrade BTA was developed by integrating falling water film dielec. barrier discharge (DBD) plasma with peroxymonosulfate (PMS) or persulfate (PS). BTA degradation was significantly improved (47%) by adding PMS to the DBD plasma system; in addition, the energy yield increased 84%. Enhanced degradation efficiency was attributed to PMS activation which enriched the active species and increased the DBD plasma system oxidation potential. Radical scavenger experiments showed that SO4– and OH– radicals contribute to BTA degradation, but the latter had greater direct impact on BTA degradation Superoxide radicals, singlet oxygen, and electrons also played an important role in the DBD-PMS system. BTA degradation intermediates and proposed reaction pathways were identified, including hydroxylation, cleavage, and coupling reactions. Intermediates toxicity anal. demonstrated toxicity of oral rat LD50 and BTA developmental toxicity were alleviated. Overall, integrated DBD and PMS is a promising technol. for efficient, economic, environment-friendly refractory pollutant removal from water. In the experiment, the researchers used many compounds, for example, 1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6Recommanded Product: 1H-1,2,3-Triazole-4,5-dicarboxylic acid).

1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6) belongs to triazole derivatives. Many triazoles are versatile, biologically active compounds commonly used as fungicides and plant retardants. Triazole growth retardants such as uniconazole and paclobutrazol have been known to inhibit the biosynthesis of gibberellins by blocking kaurene oxidase, an P450 enzymeRecommanded Product: 1H-1,2,3-Triazole-4,5-dicarboxylic acid

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Zou, Ji-Yong et al. published their research in CrystEngComm in 2014 | CAS: 4546-95-6

1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6) belongs to triazole derivatives. Among the nitrogen-containing heterocyclic compounds, triazoles emerge with superior pharmacological applications. Both the triazoles and their derivatives have significant biological properties including antimicrobial, antiviral, antitubercular, anticancer, anticonvulsant, analgesic, antioxidant, anti-inflammatory, and antidepressant activities.Product Details of 4546-95-6

Alkaline cation directed structural diversity of cubic-cage-based cobalt(II) metal-organic frameworks: from pcu to bct net was written by Zou, Ji-Yong;Shi, Wei;Zhang, Jing-Ya;He, Yan-Fei;Gao, Hong-Ling;Cui, Jian-Zhong;Cheng, Peng. And the article was included in CrystEngComm in 2014.Product Details of 4546-95-6 This article mentions the following:

Three 2p-3d heterometallic cubic-cage-based metal-organic frameworks (MOFs), formulated as {[H2N(CH3)2]9(H3O)6[Co(H2O)6][Co8Li3(TDA)12]·14H2O}n (1), {(H3O)15[Co(H2O)6][Co8Li3(TDA)12]·10H2O}n (2) and {[H2N(CH3)2](H3O)16[Co8K5(μ2-O)(TDA)12(H2O)2]·10H2O}n (3) (H3TDA = 1H-1,2,3-triazole-4,5-dicarboxylic acid), have been successfully synthesized and structurally characterized. In these 2p-3d heterometallic cubic-cage-based MOFs, eight Co2+ cations as the vertexes are interconnected by twelve TDA3- ligands as the edges to form an unusual [Co8(TDA)12]20- cubic cage with edges of 6.12 Å, in which a hexahydrated Co2+ ion is captured for 1 and 2. The neighboring [Co8(TDA)12]20- cubic cages are further bridged by Li+ ions for 1 and 2 and K+ ions for 3 to give 3D 6-connected pcu nets for 1 and 2 and a 10-connected bct net for 3. The magnetic properties of 1–3 were studied. In the experiment, the researchers used many compounds, for example, 1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6Product Details of 4546-95-6).

1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6) belongs to triazole derivatives. Among the nitrogen-containing heterocyclic compounds, triazoles emerge with superior pharmacological applications. Both the triazoles and their derivatives have significant biological properties including antimicrobial, antiviral, antitubercular, anticancer, anticonvulsant, analgesic, antioxidant, anti-inflammatory, and antidepressant activities.Product Details of 4546-95-6

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

De Robertis, Alessandro et al. published their research in Journal of Chemical Research, Synopses in 1995 | CAS: 4546-95-6

1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6) belongs to triazole derivatives. Many triazoles are versatile, biologically active compounds commonly used as fungicides and plant retardants. 1,2,3-Triazoles are usually prepared following (3+2) cycloaddition protocols. A common technique for unsubstituted triazoles is the Huisgen azide-alkyne 1,3-dipolar cycloaddition: a azide and an alkyne react at high temperature to form a ring. However, the Huisgen strategy produces a mixture of isomers (typically 1,4- and 1,5-disubstituted) when used to produce substituted triazoles.Synthetic Route of C4H3N3O4

Ionic strength dependence of formation constants. Part 20. Salt effects on the protonation of 1H-1,2,3-trazole-4,5-dicarboxylic acid in aqueous solution was written by De Robertis, Alessandro;Foti, Claudia;Gianguzza, Antonio. And the article was included in Journal of Chemical Research, Synopses in 1995.Synthetic Route of C4H3N3O4 This article mentions the following:

The dependence on ionic strength of the protonation constants of 1H-1,2,3-triazole-4,5-dicarboxylic acid has been studied in Et4NI, NaCl and CaCl2 aqueous solution, and it has been found that the complexation behavior of this ligand is very similar to that of tricarboxylic acids. In the experiment, the researchers used many compounds, for example, 1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6Synthetic Route of C4H3N3O4).

1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6) belongs to triazole derivatives. Many triazoles are versatile, biologically active compounds commonly used as fungicides and plant retardants. 1,2,3-Triazoles are usually prepared following (3+2) cycloaddition protocols. A common technique for unsubstituted triazoles is the Huisgen azide-alkyne 1,3-dipolar cycloaddition: a azide and an alkyne react at high temperature to form a ring. However, the Huisgen strategy produces a mixture of isomers (typically 1,4- and 1,5-disubstituted) when used to produce substituted triazoles.Synthetic Route of C4H3N3O4

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Zheng, Ze-Bao et al. published their research in Journal of Molecular Structure in 2009 | CAS: 4546-95-6

1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6) belongs to triazole derivatives. However, triazoles are also useful in bioorthogonal chemistry, because the large number of nitrogen atoms causes triazoles to react similar to azides. The presence of the three nitrogen atoms in triazole structures afforded opportunities for a plethora of structural modification with the generation of novel therapeutically potential agents, which is different from other heterocyclic compounds.Formula: C4H3N3O4

Hydrothermal syntheses and structural characterization of four complexes with in situ formation of 1,2,3-triazole-4-carboxylate ligand was written by Zheng, Ze-Bao;Wu, Ren-Tao;Li, Ji-Kun;Sun, Yi-Feng. And the article was included in Journal of Molecular Structure in 2009.Formula: C4H3N3O4 This article mentions the following:

Four new complexes constructed with 1,2,3-triazole-4-carboxylate and bipyridyl-like ligands, [Cu(ta)(bipy)·H2O]n (1), [Mn2(ta)2(bipy)2(H2O)2·2H2O]n (2), [Zn(ta)(phen)2·5H2O]n (3) and [Ni(ta)(phen)2·8H2O]n (4) (ta = 1,2,3-triazole-4-carboxylate, bipy = 2,2′-bipyridine, phen = 1,10-phenanthroline), were prepared under hydrothermal conditions and characterized by IR, elemental analyses and single-crystal x-ray analyses. The ta ligand is formed in situ by the decarboxylation of 1H-1,2,3-triazole-4,5-dicarboxylic acid. In the complex 1, the Cu(II) ions are bridged by ta ligand into a 1-dimensional zigzag chain coordination polymer motif. Binuclear [Mn2(ta)2(bipy)2(H2O)2] units bridged by ta ligands are linked into a two-dimensional layered structure via interdimeric hydrogen bonds within the structure of 2. Compounds 3 and 4 are mononuclear complexes. Most interestingly, the crystal-lattice water mols. in complexes 3 and 4 are connected via intermol. O-H···O hydrogen bonds into 1-dimensional tapes and 2-dimensional layers, resp. In the experiment, the researchers used many compounds, for example, 1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6Formula: C4H3N3O4).

1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6) belongs to triazole derivatives. However, triazoles are also useful in bioorthogonal chemistry, because the large number of nitrogen atoms causes triazoles to react similar to azides. The presence of the three nitrogen atoms in triazole structures afforded opportunities for a plethora of structural modification with the generation of novel therapeutically potential agents, which is different from other heterocyclic compounds.Formula: C4H3N3O4

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Zou, Ji-Yong et al. published their research in Chemical Communications (Cambridge, United Kingdom) in 2013 | CAS: 4546-95-6

1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6) belongs to triazole derivatives. The triazole ring is a relatively stable functional group, and the triazole bond can be used for a variety of applications, such as replacing the phosphate backbone of DNA. Due to the structural characteristics, both 1,2,3- and 1,2,4-triazoles are able to accommodate a broad range of substituents (electrophiles and nucleophiles) around the core structures and pave the way for the construction of diverse novel bioactive molecules.SDS of cas: 4546-95-6

A homospin cobalt(II) topological ferrimagnet was written by Zou, Ji-Yong;Shi, Wei;Xu, Na;Li, Lei-Lei;Tang, Jin-Kui;Gao, Hong-Ling;Cui, Jian-Zhong;Cheng, Peng. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2013.SDS of cas: 4546-95-6 This article mentions the following:

An unusual 3D homospin Co(II) mol. topol. ferrimagnet was successfully assembled using a mixed ligand approach, which shows a critical temperature of 9 K and a compensation temperature of 5 K. Crystal data: orthorhombic, Fddd, a = 15.6139(8), b = 18.3439(11), c = 34.336(3) Å, Z = 16, R1 = 0.0490, wR2 = 0.1473 [I > 2σ(I)]. In the experiment, the researchers used many compounds, for example, 1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6SDS of cas: 4546-95-6).

1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6) belongs to triazole derivatives. The triazole ring is a relatively stable functional group, and the triazole bond can be used for a variety of applications, such as replacing the phosphate backbone of DNA. Due to the structural characteristics, both 1,2,3- and 1,2,4-triazoles are able to accommodate a broad range of substituents (electrophiles and nucleophiles) around the core structures and pave the way for the construction of diverse novel bioactive molecules.SDS of cas: 4546-95-6

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Zhou, Xin-Hui et al. published their research in Crystallography Reports in 2017 | CAS: 4546-95-6

1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6) belongs to triazole derivatives. Triazoles consist of a five-membered ring containing three nitrogen atoms and are biologically active, especially as antifungal, antimicrobial and enzyme inhibitors. The presence of the three nitrogen atoms in triazole structures afforded opportunities for a plethora of structural modification with the generation of novel therapeutically potential agents, which is different from other heterocyclic compounds.Computed Properties of C4H3N3O4

A three-dimensional coordination polymer based on 1,2,3-triazole-4,5-dicarboxylic acid (H3tda): {[Cd12(tda)8(H2O)11]·(H2O)6.25}n was written by Zhou, Xin-Hui;Chen, Qiang. And the article was included in Crystallography Reports in 2017.Computed Properties of C4H3N3O4 This article mentions the following:

The title coordination polymer {[Cd12(tda)8(H2O)11]·(H2O)6.25}n (H3tda = 1,2,3-triazole-4,5-dicarboxylic acid), has been hydrothermally synthesized and structurally characterized by single-crystal x-ray diffraction. Complex crystallizes in orthorhombic sp. gr. Pmn21 with Z = 4. The Cd2 unit doublebridged by one carboxylate oxygen atom and two neighboring nitrogen atoms from the tda3- ligands are linked by the tda3-ligands to lead to the 2D (4,4) network in the ac plane. The almost coplanar Cd2(μ5-tda)2 unit comprised of two Cd ions double-bridged by two tda3- ligands through the neighboring nitrogen atoms is connected with the other four Cd2(μ5-tda)2 units form the undulating 2D network in the ac plane. The (4,4) networks and undulating 2D networks are alternatively connected along the b axis by the tda3- ligands coordinating to the Cd ions to form the 3D framework. In the experiment, the researchers used many compounds, for example, 1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6Computed Properties of C4H3N3O4).

1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6) belongs to triazole derivatives. Triazoles consist of a five-membered ring containing three nitrogen atoms and are biologically active, especially as antifungal, antimicrobial and enzyme inhibitors. The presence of the three nitrogen atoms in triazole structures afforded opportunities for a plethora of structural modification with the generation of novel therapeutically potential agents, which is different from other heterocyclic compounds.Computed Properties of C4H3N3O4

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Liu, Jiang et al. published their research in Chemical Communications (Cambridge, United Kingdom) in 2017 | CAS: 4546-95-6

1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6) belongs to triazole derivatives. Triazoles are important five-member nitrogen heterocycles involved in a wide range of industrial applications such as agrochemicals, corrosion inhibitors, dyes, optical brighteners, as well as biologically active agents.Triazole heterocyclic structures are found to form many weak nonbond interactions with the receptors and enzymes in biological systems.Electric Literature of C4H3N3O4

Controllable porosity conversion of metal-organic frameworks composed of natural ingredients for drug delivery was written by Liu, Jiang;Bao, Tian-Yi;Yang, Xi-Ya;Zhu, Pei-Pei;Wu, Lian-He;Sha, Jing-Quan;Zhang, Lei;Dong, Long-Zhang;Cao, Xue-Li;Lan, Ya-Qian. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2017.Electric Literature of C4H3N3O4 This article mentions the following:

Two extremely rare β-cyclodextrin (β-CD) supported metal-organic frameworks (MOFs), CD-MOF-1 and CD-MOF-2, were induced to crystallize for the first time through a template-induced approach. The targeted CD-MOFs were employed to perform controlled drug delivery and cytotoxicity assays that confirmed their favorable biol. potential of being used as drug carriers. In the experiment, the researchers used many compounds, for example, 1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6Electric Literature of C4H3N3O4).

1H-1,2,3-Triazole-4,5-dicarboxylic acid (cas: 4546-95-6) belongs to triazole derivatives. Triazoles are important five-member nitrogen heterocycles involved in a wide range of industrial applications such as agrochemicals, corrosion inhibitors, dyes, optical brighteners, as well as biologically active agents.Triazole heterocyclic structures are found to form many weak nonbond interactions with the receptors and enzymes in biological systems.Electric Literature of C4H3N3O4

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics