Yamazaki, Chisato M.’s team published research in Nature Communications in 2021 | CAS: 510758-28-8

Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8) can stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.Recommanded Product: 510758-28-8Polytriazolylamines were synthesized by the copper(I)-catalyzed ligation of azides and alkynes.

Yamazaki, Chisato M.; Yamaguchi, Aiko; Anami, Yasuaki; Xiong, Wei; Otani, Yoshihiro; Lee, Jangsoon; Ueno, Naoto T.; Zhang, Ningyan; An, Zhiqiang; Tsuchikama, Kyoji published their research in Nature Communications in 2021. The article was titled 《Antibody-drug conjugates with dual payloads for combating breast tumor heterogeneity and drug resistance》.Recommanded Product: 510758-28-8 The article contains the following contents:

Breast tumors generally consist of a diverse population of cells with varying gene expression profiles. Breast tumor heterogeneity is a major factor contributing to drug resistance, recurrence, and metastasis after chemotherapy. Antibody-drug conjugates (ADCs) are emerging chemotherapeutic agents with striking clin. success, including T-DM1 for HER2-pos. breast cancer. However, these ADCs often suffer from issues associated with intratumor heterogeneity. Here, we show that homogeneous ADCs containing two distinct payloads are a promising drug class for addressing this clin. challenge. Our conjugates show HER2-specific cell killing potency, desirable pharmacokinetic profiles, minimal inflammatory response, and marginal toxicity at therapeutic doses. Notably, a dual-drug ADC exerts greater treatment effect and survival benefit than does co-administration of two single-drug variants in xenograft mouse models representing intratumor HER2 heterogeneity and elevated drug resistance. Our findings highlight the therapeutic potential of the dual-drug ADC format for treating refractory breast cancer and perhaps other cancers. In the experiment, the researchers used Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8Recommanded Product: 510758-28-8)

Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8) can stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.Recommanded Product: 510758-28-8Polytriazolylamines were synthesized by the copper(I)-catalyzed ligation of azides and alkynes.

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Steinmeyer, Jeannine’s team published research in Bioconjugate Chemistry in 2018 | CAS: 510758-28-8

Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8) can stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.Application In Synthesis of Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)aminePolytriazolylamines were synthesized by the copper(I)-catalyzed ligation of azides and alkynes.

In 2018,Steinmeyer, Jeannine; Wagenknecht, Hans-Achim published 《Synthesis of DNA Modified with Boronic Acid: Compatibility to Copper(I)-Catalyzed Azide-Alkyne Cycloaddition》.Bioconjugate Chemistry published the findings.Application In Synthesis of Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine The information in the text is summarized as follows:

The postsynthetic and sequence specific ligation chem. of a phenylboronic acid to oligonucleotides using the amide bond formation was worked out. In the first coupling experiments with 4 carboxyphenylboronic acid a 5′-hexylamino-modified oligonucleotide was used in order to evaluate and to optimize the reaction conditions. This postsynthetic modification works best in the presence of TBTU and triethanolamine and in a degassed DMF/carbonate buffer solvent mixture The successful attachment of the boronic acid was evidenced by HPLC separation from phenol side products and clear identification via MALDI-TOF mass spectrometry as citric acid derivative This postsynthetic chem. was further combined with the established Cu(I)-catalyzed azide-alkyne cycloaddition chem. to allow the first orthogonal and postsynthetic incorporation of both the phenylboronic acid moiety and two different cyanine-styryl dyes. Due to the undesired reactivity of boronic acids by the presence of copper salts, the dye azides were firstly attached to the pre-synthesized oligonucleotides using the Cu(I)-catalyzed cycloaddition at the 2′-position of a propargylated uridine. After careful removal of all copper contaminants the amide bond with the 4-carboxyphenylboronic acid at the propylamine linker of a 7-deaza-2′-deoxyadenosine as anchor point was formed. These doubly modified oligonucleotides were characterized by their optical properties to elucidate the influence of the phenylboronic acid. The latter modification has only little influence on the fluorescence of the applied dyes. In conclusion, this postsynthetic and orthogonal chem. opens the way to a broad variety of applications, in particular saccharide detection based on fluorescent DNA aptamers.Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8Application In Synthesis of Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine) was used in this study.

Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8) can stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.Application In Synthesis of Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)aminePolytriazolylamines were synthesized by the copper(I)-catalyzed ligation of azides and alkynes.

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Wu, Guolin’s team published research in Organic & Biomolecular Chemistry in 2019 | CAS: 510758-28-8

Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8) can stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.Formula: C30H30N10

The author of 《Identification of HSP90 as a direct target of artemisinin for its anti-inflammatory activity via quantitative chemical proteomics》 were Wu, Guolin; Cheng, Bao; Qian, Hui; Ma, Shengming; Chen, Qin. And the article was published in Organic & Biomolecular Chemistry in 2019. Formula: C30H30N10 The author mentioned the following in the article:

The anti-malarial drug artemisinin (ART) possesses potent antiinflammatory activity, yet its underlying mechanism of action has remained elusive. Here the authors employed quant. chem. proteomics to in situ profile the cellular targets of ART and identified heat shock protein 90 (HSP90) as a direct target. Further study revealed that ART suppressed the production of nitric oxide (NO) in macrophages via inhibiting the interaction between HSP90 and inducible NO synthase (iNOS).Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8Formula: C30H30N10) was used in this study.

Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8) can stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.Formula: C30H30N10

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Oh, Takahiro’s team published research in Polymer Journal (Tokyo, Japan) in 2019 | CAS: 510758-28-8

Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8) can stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.Quality Control of Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine

The author of 《Preparation of multifunctional glycopolymers using double orthogonal reactions and the effect of electrostatic groups on the glycopolymer-lectin interaction》 were Oh, Takahiro; Jono, Kazuki; Kimoto, Yuri; Hoshino, Yu; Miura, Yoshiko. And the article was published in Polymer Journal (Tokyo, Japan) in 2019. Quality Control of Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine The author mentioned the following in the article:

We investigated synthetic biomacromols. to control mol. interactions. Multifunctional glycopolymers for mol. recognition were prepared via living radical polymerization and post-click chem. with orthogonal Huisgen and thiol-epoxy reactions. The synthesis of the polymer backbone and the subsequent side-chain introduction successfully proceeded in high yield. The multifunctional glycopolymers had a tri-block structure: the first and third blocks contained mannose, and the second block contained either a pos. or neg. charged group or a neutral hydrophilic group. The mol. recognition of the glycopolymers toward lectin was evaluated via fluorescence quenching measurements. Because of the electrostatic interaction, the binding constant varied in the following order: pos. charged glycopolymer (PT110) > neg. charged glycopolymer (NT110). The effect of the electrostatic interactions was modest compared with the effect of the carbohydrate-lectin binding. These results suggested that the carbohydrate-lectin interaction was an important factor in the mol. recognition of glycopolymers. This study provides guidelines for the preparation of multifunctional polymers, such as biomaterials.Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8Quality Control of Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine) was used in this study.

Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8) can stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.Quality Control of Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Heise, Torben’s team published research in Journal of Medicinal Chemistry in 2019 | CAS: 510758-28-8

Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8) can stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.Related Products of 510758-28-8

The author of 《Potent Metabolic Sialylation Inhibitors Based on C-5-Modified Fluorinated Sialic Acids》 were Heise, Torben; Pijnenborg, Johan F. A.; Buell, Christian; van Hilten, Niek; Kers-Rebel, Esther D.; Balneger, Natasja; Elferink, Hidde; Adema, Gosse J.; Boltje, Thomas J.. And the article was published in Journal of Medicinal Chemistry in 2019. Related Products of 510758-28-8 The author mentioned the following in the article:

Sialic acid sugars on mammalian cells regulate numerous biol. processes, while aberrant expression of sialic acid is associated with diseases such as cancer and pathogenic infection. Inhibition of the sialic acid biosynthesis may therefore hold considerable therapeutic potential. To effectively decrease the sialic acid expression, we synthesized C-5-modified 3-fluoro sialic acid sialyltransferase inhibitors. We found that C-5 carbamates significantly enhanced and prolonged the inhibitory activity in multiple mouse and human cell lines. As an underlying mechanism, we have identified that carbamate-modified 3-fluoro sialic acid inhibitors are more efficiently metabolized to their active cytidine monophosphate analogs, reaching higher effective inhibitor concentrations inside cells. In addition to this study using Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine, there are many other studies that have used Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8Related Products of 510758-28-8) was used in this study.

Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8) can stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.Related Products of 510758-28-8

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Guo, Huijuan’s team published research in Chemistry – A European Journal in 2018 | CAS: 510758-28-8

Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8) is a polytriazolylamine ligand which stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.Quality Control of Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine

《Expanding the Rubterolone Family: Intrinsic Reactivity and Directed Diversification of PKS-derived Pyrans》 was written by Guo, Huijuan; Benndorf, Rene; Koenig, Stefanie; Leichnitz, Daniel; Weigel, Christiane; Peschel, Gundela; Berthel, Patrick; Kaiser, Marcel; Steinbeck, Christoph; Werz, Oliver; Poulsen, Michael; Beemelmanns, Christine. Quality Control of Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amineThis research focused ontropolone alkaloid biosynthesis antimicrobial cytotoxic antiinflammatory antiparasitic activity; biosynthetic pathway; chemical probes; natural products; polyketides; tropolone alkaloids. The article conveys some information:

We characterized two key biosynthetic intermediates of the intriguing rubterolone family (tropolone alkaloids) that contain a highly reactive pyran moiety (in equilibrium with the hydrolyzed 1,5-dione form) and undergo spontaneous pyridine formation in the presence of primary amines. We exploited the intrinsic reactivity of the pyran moiety and isolated several new rubterolone derivatives, two of which contain a unique thiazolidine moiety, e.g., I. Three rubterolone derivatives were chem. modified with fluorescence and biotin tags using peptide coupling and click reaction. Overall, eight derivatives were fully characterized by HRMS/MS and 1D and 2D NMR spectroscopy and their antimicrobial, cytotoxic, anti-inflammatory and antiparasitic activities evaluated. In addition to this study using Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine, there are many other studies that have used Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8Quality Control of Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine) was used in this study.

Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8) is a polytriazolylamine ligand which stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.Quality Control of Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Zhang, Aigui’s team published research in Chemistry – A European Journal in 2022 | CAS: 510758-28-8

Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8) is a polytriazolylamine ligand which stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.Recommanded Product: 510758-28-8

Recommanded Product: 510758-28-8In 2022 ,《Anomeric DNA: Functionalization of α-D Anomers of 7-Deaza-2′-deoxyadenosine and 2′-Deoxyuridine with Clickable Side Chains and Click Adducts in Homochiral and Heterochiral Double Helices》 was published in Chemistry – A European Journal. The article was written by Zhang, Aigui; Leonard, Peter; Seela, Frank. The article contains the following contents:

Anomeric base pairs in heterochiral DNA with strands in the α-D and β-D configurations and homochiral DNA with both strands in α-D configuration were functionalized. The α-D anomers of 2′-deoxyuridine and 7-deaza-2′-deoxyadenosine were synthesized and functionalized with clickable octadiynyl side chains. Nucleosides were protected and converted to phosphoramidites. Solid-phase synthesis furnished 12-mer oligonucleotides, which were hybridized. Pyrene click adducts display fluorescence, a few of them with excimer emission. Tm values and thermodn. data revealed the following order of duplex stability α/α-D≫β/β-D≥α/β-D. CD spectra disclosed that conformational changes occur during hybridization. Functionalized DNAs were modeled and energy minimized. Clickable side chains and bulky click adducts are well accommodated in the grooves of anomeric DNA. The investigation shows for the first time that anomeric DNAs can be functionalized in the same way as canonical DNA for potential applications in nucleic acid chem., chem. biol., and DNA material science. The results came from multiple reactions, including the reaction of Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8Recommanded Product: 510758-28-8)

Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8) is a polytriazolylamine ligand which stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.Recommanded Product: 510758-28-8

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Henning, Irene’s team published research in Advanced Functional Materials in 2020 | CAS: 510758-28-8

Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8) can stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.Product Details of 510758-28-8Polytriazolylamines were synthesized by the copper(I)-catalyzed ligation of azides and alkynes.

《A Click Chemistry Strategy for the Synthesis of Efficient Photoinitiators for Two-Photon Polymerization》 was published in Advanced Functional Materials in 2020. These research results belong to Henning, Irene; Woodward, Adam W.; Rance, Graham A.; Paul, Benjamin T.; Wildman, Ricky D.; Irvine, Derek J.; Moore, Jonathan C.. Product Details of 510758-28-8 The article mentions the following:

It is reported that efficient photoinitiators, suitable for two-photon polymerization, can be obtained using the copper catalyzed azide/alkyne cycloaddition reaction. This click chem. strategy provides a modular approach to the assembly of photoinitiators that enables the rapid variation of key fragments to produce photoinitiators with desirable properties. To assess the performance of the first-in-class photoinitiators generated by this approach, a screening method is developed to enable the rapid determination of polymerization and damage thresholds in numerous photoresists during two-photon polymerization The degree of consumption of vinyl groups (DC) and homogeneity of the polymerization are further assessed by micro-Raman spectroscopy. Finally, more complex structures are fabricated to demonstrate that the efficient two-photon polymerization of stable 3D microarchitectures can be achieved using triazole-based photoinitiators. In the part of experimental materials, we found many familiar compounds, such as Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8Product Details of 510758-28-8)

Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8) can stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.Product Details of 510758-28-8Polytriazolylamines were synthesized by the copper(I)-catalyzed ligation of azides and alkynes.

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Keivanloo, Ali’s team published research in Polycyclic Aromatic Compounds in 2022 | CAS: 510758-28-8

Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8) can stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.HPLC of Formula: 510758-28-8

In 2022,Keivanloo, Ali; Abbaspour, Sima; Sepehri, Saghi; Bakherad, Mohammad published an article in Polycyclic Aromatic Compounds. The title of the article was 《Synthesis, Antibacterial Activity and Molecular Docking Study of a Series of 1,3-Oxazole-Quinoxaline Amine Hybrids》.HPLC of Formula: 510758-28-8 The author mentioned the following in the article:

A series of 1,3-oxazole-quinoxaline amine hybrids I (R = -NHMe, -NHBn, morpholin-4-yl, etc.; X = H, Cl) were prepared successfully through a copper-free Sonogashira coupling followed by heteroannulation in a one-pot process. The reaction of benzoyl chlorides, prop-2-yn-1-amine, and 2-amine-substituted 3-chloroquinoxalines catalyzed by Pd(Ph3P)2Cl2 in the presence of tris(benzyltriazolylmethyl)amine (TBTA) as an efficient ligand in EtOH produced 1,3-oxazole-quinoxaline amine hybrids in high yields. All the synthesized 1,3-oxazole-quinoxaline amine hybrids were screened for antibacterial properties and were exposed to mol. docking studies. Mol. docking study manifested the possible binding mode of compounds with its bacterial target protein. The consequences of biol. activity and docking study disclosed that the increase of lipophilic and extra hydrogen bond characters are essential for suitable antibacterial activity. In the part of experimental materials, we found many familiar compounds, such as Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8HPLC of Formula: 510758-28-8)

Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8) can stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.HPLC of Formula: 510758-28-8

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Shaw, Scott K.’s team published research in Chemistry – A European Journal in 2018 | CAS: 510758-28-8

Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8) can stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.Electric Literature of C30H30N10Polytriazolylamines were synthesized by the copper(I)-catalyzed ligation of azides and alkynes.

In 2018,Shaw, Scott K.; Liu, Wenqi; Gomez Duran, Cesar Fernando Azael; Schreiber, Cynthia L.; de Lourdes Betancourt Mendiola, Maria; Zhai, Canjia; Roland, Felicia M.; Padanilam, Simon J.; Smith, Bradley D. published 《Non-Covalently Pre-Assembled High-Performance Near-Infrared Fluorescent Molecular Probes for Cancer Imaging》.Chemistry – A European Journal published the findings.Electric Literature of C30H30N10 The information in the text is summarized as follows:

New fluorescent mol. probes, which can selectively target specific cell surface receptors, are needed for microscopy, in vivo imaging, and image guided surgery. The preparation of multivalent probes using standard synthetic chem. can be a laborious process due to low reaction yields caused by steric effects. In this study, fluorescent mol. probes were prepared by a programmed non-covalent pre-assembly process that used a near-IR fluorescent squaraine dye to thread a macrocycle bearing a cyclic arginine-glycine-aspartate peptide antagonist (cRGDfK) as a cancer targeting unit. Cell microscopy studies using OVCAR-4 (ovarian cancer) and A549 (lung cancer) cells that express high levels of the integrin αvβ3 or αvβ5 receptors, resp., revealed a multivalent cell targeting effect. That is, there was comparatively more cell uptake of a pre-assembled probe equipped with two copies of the cRGDfK antagonist than a pre-assembled probe with only one appended cRGDfK antagonist. The remarkably high photostability and low phototoxicity of these near-IR probes allowed for acquisition of long-term fluorescence movies showing endosome trafficking in living cells. In vivo near-IR fluorescence imaging experiments compared the biodistribution of a targeted and untargeted probe in a xenograft mouse tumor model. The average tumor-to-muscle ratio for the pre-assembled targeted probe was 3.6 which matches the tumor targeting performance reported for analogous cRGDfK-based probes that were prepared entirely by covalent synthesis. The capability to excite these pre-assembled near-IR fluorescent probes with blue or deep-red excitation light makes it possible to determine if a target site is located superficially or buried in tissue, a probe performance feature that is likely to be very helpful for eventual applications such as fluorescence guided surgery. In the experiment, the researchers used Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8Electric Literature of C30H30N10)

Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine(cas: 510758-28-8) can stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.Electric Literature of C30H30N10Polytriazolylamines were synthesized by the copper(I)-catalyzed ligation of azides and alkynes.

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics