Category: 77-85-0

Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 77-85-0, Name is 1,1,1-Tris(hydroxymethyl)ethane, molecular formula is , belongs to Triazoles compound. In a document, author is Ali, Tamer A., Name: 1,1,1-Tris(hydroxymethyl)ethane.

Ionic liquid-multi-walled carbon nanotubes modified screen-printed electrodes for sensitive electrochemical sensing of uranium

Here, two screen-printed electrodes modified with multi-walled carbon nanotubes alone (electrode III) or along with a triazole-based ionic liquid (electrode VII) were developed for sensitive uranium(VI) determination. The electrodes exhibited calibration slopes of 25.10 +/- 1.35 and 29.93 +/- 0.88 mV decade(-1) over the concentration ranges of 1.0 x 10(-5)-1.0 x 10(-1) and 4.7 x 10(-7)-1.0 x 10(-1) mol L-1 for electrodes III and VII, respectively. The electrodes showed fast response times with a service life exceeding 5 months. The electrodes revealed good thermal stability and fairly high uranium(VI) selectivity over many cations and anions. The electrodes were successfully employed for sensitive detection of uranium(VI) in different water samples.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 77-85-0, in my other articles. Name: 1,1,1-Tris(hydroxymethyl)ethane.

Chemistry is an experimental science, Recommanded Product: 1,1,1-Tris(hydroxymethyl)ethane, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 77-85-0, Name is 1,1,1-Tris(hydroxymethyl)ethane, molecular formula is C5H12O3, belongs to Triazoles compound. In a document, author is Li, Xin.

[N-N=N-N]-linked fused triazoles with pi-pi stacking and hydrogen bonds: Towards thermally stable, Insensitive, and highly energetic materials

It is the main task and challenge to reach a fine balance between high energy density and good molecular stability in energetic material research. In this study, two series of energetic compounds, 3-amino-7,7′-azo-[1,2,4] triazolo[4,3-b][1,2,4]triazole and 3,6-diamino-7,7′-azo-[1,2,4]triazolo[4,3-b][1,2,4] triazole featuring the N-4 [N-N=N-N] linkage and fused triazoles, are presented. Their structures were determined by single crystal X-ray diffraction, elemental analysis, NMR, and IR spectroscopy. Their properties were studied in terms of density, thermal stability, detonation performance, and mechanical sensitivity. The N-4 [N-N=N-N] linkages accord these compounds with high heat of formation, thus increasing the detonation performance. All fused triazoles exhibit planar structures, which result in low mechanical sensitivity. Through careful investigation of crystal data, strong pi-pi stacking and extensive hydrogen-bonding interactions were observed between molecules, which gives positive impact on mechanical sensitivity and thermal stability. The properties between different cations (or ions) were carefully studied. Quantum chemistry calculations were performed to investigate the potential relationship between structures and properties. Among them, compound 5 possesses high thermal stability (T-d: 275 degrees C), good detonation performance (D: 8677 m s(-1); P: 36.1 GPa), and excellent insensitivity (IS: 40 J; FS: 360 N), which makes it a balanced and promising energetic material.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 77-85-0, in my other articles. Recommanded Product: 1,1,1-Tris(hydroxymethyl)ethane.

Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 77-85-0, Name is 1,1,1-Tris(hydroxymethyl)ethane, molecular formula is C5H12O3, belongs to Triazoles compound. In a document, author is Abu-Hashem, Ameen Ali, introduce the new discover, Recommanded Product: 77-85-0.

Synthesis of new pyrazoles, oxadiazoles, triazoles, pyrrolotriazines, and pyrrolotriazepines as potential cytotoxic agents

4-Oxo-4-phenylbutanehydrazide (1) reacted with many active methylene reagents such as acetylacetone, diethylmalonate, ethylacetoacetate, ethylcyanoacetate, benzoyl-acetonitrile, and malononitrile under neat conditions to afford the corresponding pyrazoles (2-7), also, treatment of butanehydrazide (1) with electrophilic reagents as triethylorthoformate, dimethylformamide-dimethylacetal, acetic anhydride, and carbon disulfide to give 1,3,4-oxadiazoles (8,10,11) and N ‘-acetyl-butanehydrazide (9). Reacted of butanehydrazide (1) with potassium thiocyanate gave 1,2,4-triazoles (12). Similarly, treatment of (1) with chloroacetamide gave 1,2,4-triazinones (13). The pyrrolotriazinones (14) was obtained by cyclization of (13). Also, butanehydrazide (1) was utilized as a starting material for the synthesized of new Schiff bases as N ‘-(4-sub-benzylidene)-phenylbutane-hydrazide (15a-c), which are used as an initiative to prepare new compounds such as 1,2,4-triazepinones (16a-c), pyrrolotriazepinones (17a-c), 1,2,4-triazines (18a-c), and pyrrolotriazines (19a-c) by reacted of (15a-c) with each chloroacetamide or formamide. The chemical structure of the newly prepared compounds was determined through the spectrum data, including IR, NMR, and MS. The prepared compounds were tested for their in vitro antitumor activities. The compounds 17a-c, 16a-c, and 19a-c displayed activity against several types of cancer cell lines.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 77-85-0. Recommanded Product: 77-85-0.

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 77-85-0, Name is 1,1,1-Tris(hydroxymethyl)ethane, SMILES is CC(CO)(CO)CO, in an article , author is Nehra, Nidhi, once mentioned of 77-85-0, Category: Triazoles.

CuAAC Mediated Synthesis of 2-HBT Linked Bioactive 1,2,3-Triazole Hybrids: Investigations through Fluorescence, DNA Binding, Molecular Docking, ADME Predictions and DFT Study

A series of three different classes of benzothiazole linked 1,2,3-triazole hybrid molecules with varying alkyl spacers (ethyl, propyl, and butyl) between 2-hydroxyphenyl benzothiazoles and 1,2,3-triazoles are efficiently synthesized under CuAAC condition. All compounds are satisfactorily characterized by FTIR, H-1-NMR, C-13-NMR, ESI-MS data and structures of some compounds were finally supported by single-crystal X-ray diffraction data. Most of the synthesized compounds exhibited good to better DNA binding property (0.28×10(5) M-1 to 2.91×10(5) M-1) and well drug-like properties. Some promising compounds showed good agreement to all experimental and theoretical computed properties (fluorescence study, DNA binding, molecular docking, DFT, and ADME Predictions).

Interested yet? Read on for other articles about 77-85-0, you can contact me at any time and look forward to more communication. Category: Triazoles.

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 77-85-0, Name is 1,1,1-Tris(hydroxymethyl)ethane, molecular formula is C5H12O3. In an article, author is Liao, Kui,once mentioned of 77-85-0, Computed Properties of C5H12O3.

Highly Enantioselective CuAAC of Functional Tertiary Alcohols Featuring an Ethynyl Group and Their Kinetic Resolution

The first highly enantioselective Cu-I-catalyzed azide-alkyne cycloaddition (CuAAC) of tertiary alcohols and their kinetic resolution is reported. This approach allows facile access to multifunctional tertiary alcohols featuring an alpha-ethynyl or alpha-triazole moiety, and represents the first successful kinetic resolution of racemates with a tetrasubstituted carbon stereocenter via CuAAC. Newly developed pyridinebisoxazoline (PYBOX) ligands with a C4 phosphonate group play a key role.

Interested yet? Keep reading other articles of 77-85-0, you can contact me at any time and look forward to more communication. Computed Properties of C5H12O3.

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 77-85-0, Name is 1,1,1-Tris(hydroxymethyl)ethane, molecular formula is , belongs to Triazoles compound. In a document, author is Saadat, Mostafa, Formula: C5H12O3.

Sulfonic acid-functionalized magnetic carbon nitride as highly efficient ionic composite for sustainable assembly of 1,2,3-triazoles

An efficient and straightforward method for constructing of biologically active 4-aryl-NH-1,2,3-triazoles by the 1,3-dipolar cycloaddition reaction of beta-nitrostyrene and sodium azide in the presence of acidic graphitic carbon nitride (Fe3O4@g-C3N4-SO3H) ionic nanocomposite has developed. Using a magnetically recoverable acidic ionic catalyst allows eco-friendly and facile conversion and simplifies experimental setup and work-up procedure that enables the direct synthesis of triazole derivatives under mild conditions. The designed catalytic system provides a broader scope under short reaction times in good to excellent yields. Fe3O4@g-C3N4-SO3H could be simply recovered by magnetic separation using an external magnet, maintaining stable activity up to five cycles without appreciable loss of activity. [GRAPHICS] .

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One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 77-85-0, Name is 1,1,1-Tris(hydroxymethyl)ethane, formurla is C5H12O3. In a document, author is Moghaddampour, Issa Mousazadeh, introducing its new discovery. Quality Control of 1,1,1-Tris(hydroxymethyl)ethane.

Agar-entrapped sulfonated DABCO: Agelly acidic catalyst for the acceleration of one-pot synthesis of 1,2,4-triazoloquinazolinone and some pyrimidine derivatives

In this project, a recently synthesized DABCO-based catalyst is entrapped in agar to reduce its moisture sensitivity leading to enhancement of its stability and catalytic activity. After preparation and identification this new reagent is used as an efficient and environmentally safe catalyst for the preparation of 1, 2, 4-triazoloquinazolinone and some pyrimidine derivatives. This method is accompanied with some superiorities such as, simple operation, mild and green conditions, use of low cost and non-hazardous natural material, short reaction times, easy preparation methods and simple work-up procedures. The prepared catalyst can be re-used for several times in all of the studied reactions without any appreciable loss in its activity. (C) 2020 Elsevier B.V. All rights reserved.

If you are hungry for even more, make sure to check my other article about 77-85-0, Quality Control of 1,1,1-Tris(hydroxymethyl)ethane.

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 77-85-0, Name is 1,1,1-Tris(hydroxymethyl)ethane, formurla is C5H12O3. In a document, author is Kasemsuk, Teerapich, introducing its new discovery. Formula: C5H12O3.

A novel synthetic acanthoic acid analogues and their cytotoxic activity in cholangiocarcinoma cells

A novel series of acanthoic acid analogues containing triazole moiety were synthesized through esterification and CuAAC reaction. Evaluation of their biological activities against four cell lines of cholangiocarcinoma cells showed that 3d exhibited the strongest activity with an IC50 value of 18 mu M against KKU-213 cell line, which was 8 fold more potent than acanthoic acid. Interestingly, the triazole ring and nitro group on benzyl ring play very significant role in cytotoxic activity. The computational studies revealed that 3d occupies the binding energy of -12.7 and -10.8 kcal/mol with CDK-2 and EGFR protein kinases, respectively. This result might provide a beginning for the development of acanthoic acid analogues as an anticancer agent.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 77-85-0 help many people in the next few years. Formula: C5H12O3.

Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 77-85-0, Name is 1,1,1-Tris(hydroxymethyl)ethane, molecular formula is C5H12O3, belongs to Triazoles compound, is a common compound. In a patnet, author is Roana, Janira, once mentioned the new application about 77-85-0, Product Details of 77-85-0.

Antifungal Activity of Melaleuca alternifolia Essential Oil (TTO) and Its Synergy with Itraconazole or Ketoconazole against Trichophyton rubrum

Over the past 20-30 years, Trichophyton rubrum represented the most widespread dermatophyte with a prevalence accounting for 70% of dermatophytosis. The treatment for cutaneous infections caused by Trichophyton spp. are imidazoles (ketoconazole (KTZ)) and triazoles (itraconazole (ITZ)). T. rubrum can develop resistance to azoles after prolonged exposure to subinhibitory concentrations resulting in therapeutic failures and chronic infections. These problems have stimulated the search for therapeutic alternatives, including essential oils, and their potential use in combination with conventional antifungals. The purpose of this study was to evaluate the antifungal activity of tea tree oil (TTO) (Melaleuca alternifolia essential oil) and the main components against T. rubrum and to assess whether TTO in association with KTZ/ITZ as reference drugs improves the antifungal activity of these drugs. We used a terpinen-4-ol chemotype (35.88%) TTO, and its antifungal properties were evaluated by minimum inhibitory and minimum fungicidal concentrations in accordance with the CLSI guidelines. The interaction between TTO and azoles was evaluated through the checkerboard and isobologram methods. The results demonstrated both the fungicide activity of TTO on T. rubrum and the synergism when it was used in combination with azoles. Therefore, this mixture may reduce the minimum effective dose of azole required and minimize the side effects of the therapy. Synergy activity offered a promise for combination topical treatment for superficial mycoses.

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Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Ouyang, Fan, once mentioned the application of 77-85-0, Name is 1,1,1-Tris(hydroxymethyl)ethane, molecular formula is C5H12O3, molecular weight is 120.147, MDL number is MFCD00004687, category is Triazoles. Now introduce a scientific discovery about this category, Category: Triazoles.

Synthesis, structures and magnetic properties of copper(II) complexes with 1,2,3-triazole derivate as ligand: a single-crystal-to-single-crystal transformation from mononuclear to polymeric complex of copper(II)

A new mononuclear complex Cu(tdp)Br-2 center dot MeCN (1, tdp = 2,2 ‘-(1H-1,2,3-triazole-1,4-diyl)dipyridine) has been synthesized, which can transform to a 1D coordination polymer [Cu(tdp)Br-2](n) (2) under ambient conditions through an irreversible single-crystal-to-single-crystal transformation process. The loss of lattice MeCN molecules in 1 was accompanied by the generation of new covalent bonds and an increase in dimensionality from 0 to 1D, leading to a change in magnetic exchange couplings between the adjacent Cu(II) ions. Magnetic susceptibility measurements indicate that 1 exhibits ferromagnetic interactions between the adjacent Cu(II) centers, while the intrachain magnetic interactions between Cu(II) ions are antiferromagnetic within 2.

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