So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Pore, Vandana S.; Aher, Nilkanth G.; Kumar, Manish; Shukla, Praveen K. researched the compound: 1-(2,4-Difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone( cas:86404-63-9 ).Safety of 1-(2,4-Difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone.They published the article 《Design and synthesis of fluconazole/bile acid conjugate using click reaction》 about this compound( cas:86404-63-9 ) in Tetrahedron. Keywords: fluconazole bile acid conjugate regioselective synthesis antifungal activity; Candida antifungal fluconazole bile acid conjugate regioselective synthesis; steroid azide preparation intermol dipolar cycloaddition triazolylpentynol. We’ll tell you more about this compound (cas:86404-63-9).
Novel fluconazole/bile acid conjugates I (R1 = H, OH) and II (R2 = H, OH) were designed and their regioselective synthesis was achieved in very high yield via Cu(I) catalyzed intermol. 1,3-dipolar cycloaddition These new mols. showed good antifungal activity against Candida species.
After consulting a lot of data, we found that this compound(86404-63-9)Safety of 1-(2,4-Difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics