New discoveries in chemical research and development in 2021. As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world.1455-77-2, name is 3,5-Diamino-1,2,4-triazole belongs to triazoles compound, it is a common compound, a new synthetic route is introduced below. Product Details of 1455-77-2
To a solution of 135.6 g (1.965 mol) of sodium nitrite in158.2 mL of water at -10 to -5 °C, we added a solution of 20 g(0.202 mol) of DAT in 423.7 mL 1.2 mol/L sulfuric acid for1.5 h. The reaction mixture was heated up to 60 °C and stirredfor another 1 h, then cooled the reaction mixture to roomtemperature. 67.2 mL 6 mol/L sulfuric acid and 11.85 g (0.121mol) aminosulfuric acid were added to reaction system andstirred for another 0.5 h, extracted with 322.5 × 3 mL of trioctylamineand 265.5 mL toluene, dried with magnesiumsulfate overnight. The magnesium sulfate was filtered and thefiltrate reacted with excess ammonia to obtain the yellow solid,dried in vacuum to give 25.1 g of 3,5-dinitro-1,2,4-triazoleammonium (AA DNT).
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 3,5-Diamino-1,2,4-triazole ,and how the biochemistry of the body works.
Reference:
Article; Li, Ya-Nan; Liu, Ning; Su, Peng-Fei; Wang, Ying-Lei; Ge, Zhong-Xue; Li, Hui; Wang, Bo-Zhou; Asian Journal of Chemistry; vol. 26; 21; (2014); p. 7151 – 7156;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics