Continuously updated synthesis method about 815588-93-3

The chemical industry reduces the impact on the environment during synthesis 1-Methyl-1H-1,2,4-triazole-5-carboxylic acid. I believe this compound will play a more active role in future production and life.

Reference of 815588-93-3, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 815588-93-3, name is 1-Methyl-1H-1,2,4-triazole-5-carboxylic acid, This compound has unique chemical properties. The synthetic route is as follows.

A mixture of 1 -methyl-1 H-1 ,2,4-triazole-5-carboxylic acid (7.0 g, 55.1 mmol) in SOCI2 (20 mL) was heated to 70 °C for 2 h. The mixture was concentrated to dryness. The residue was dissolved in Nh /MeOH (7M, 40 mL) and stirred at rt overnight. The precipitated solid was filtered off, extracted with Et20 and dried under reduced pressure to give the title compound

The chemical industry reduces the impact on the environment during synthesis 1-Methyl-1H-1,2,4-triazole-5-carboxylic acid. I believe this compound will play a more active role in future production and life.

Reference:
Patent; PHENEX PHARMACEUTICALS AG; STEENECK, Christoph; DEUSCHLE, Ulrich; ALBERS, Michael; HOFFMANN, Thomas; (64 pag.)WO2018/141855; (2018); A1;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics