In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 162848-16-0, name is 4-[1,2,4]Triazol-1-yl-benzoic acid belongs to Triazoles compound, it is a common compound, a new synthetic route is introduced below. Computed Properties of C9H7N3O2
Synthesis of N-[2,6-dibromo-4-(l,l,l,2,3,3,3-heptafluoropropan-2-yl)phenyl]-4- (1H-1,2,4- triazol-l-yl)benzamide (Compound No. 1-78).[0147] Step 1 – 1 : Synthesis of 4-( 1 H- 1 ,2,4-triazol- 1 -yl)benzoyl chloride[0148] 4-(lH-l,2,4-triazol-l-yl)benzoic acid (0.90 g) was suspended in toluene. To the suspension, thionyl chloride (5.7 g) and an catalytic amount of N,N-dimethylformamide (2 to 3 drops) were added and the mixture was refluxed under heating for 4 hours. After adjusting the reaction solution to room temperature, the solvent was distilled off under reduced pressure to obtain4-(lH-l,2,4-triazol-l-yl)-benzoyl chloride as a crude product (0.95 g). Without further purification, the crude product was used for the next reaction.
The synthetic route of 162848-16-0 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; BAYER CROPSCIENCE AG; MIHARA, Jun; ARAKI , Koichi; MORI , Takuma; MURATA , Tetsuya; YONETA, Yasushi; WATANABE , Yukiyoshi; SHIMOJO , Eiichi; ICHIHARA , Teruyuki; ATAKA , Masashi; SHIBUYA , Katsuhiko; GOeRGENS, Ulrich; WO2011/18170; (2011); A2;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics