Epstein, Samuel S.; Timmis, Geoffrey M. published the artcile< Simple antimetabolites of vitamin B12>, COA of Formula: C5H3BrN4, the main research area is .
Nearly 300 compounds (mostly benzimidazoles, diazabenzimidazoles, purines, azapurines, pteridines, azapteridines, pyrimidines, nicotinamide and p-aminobenzoic acid derivatives, imidazoles, and alloxans) which bear no structural analogy to vitamin B12 (I), were tried as antimetabolites for the I on Euglena gracilis. For 43 compds, less than 500 γ/ml. produced a 50% inhibition of growth when the I concentration was 10-11 g./ml.; 10 of these compounds produced competitive antagonism as evidenced by the reversibility of their inhibition by higher (10-10-10-9 g./ml.) concentration of I. It is suggested that such simple metabolites as above may act indirectly by interfering with cofactors concerned with the utilization of I.
Journal of Protozoology published new progress about 92276-38-5. 92276-38-5 belongs to class triazoles, and the molecular formula is C5H3BrN4, COA of Formula: C5H3BrN4.
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics