Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 65705-44-4, is researched, SMILESS is NC1=NC(C2=CC=C(Br)C=C2)=C(C)S1, Molecular C10H9BrN2SJournal, Asian Journal of Chemistry called Synthesis and antimicrobial activities of some novel 2,3-substituted-1,3-thiazolidin-4-ones derived from 2-amino-1,3-thiazole, Author is Maher, K., the main research direction is Staphylococcus Escherichia Pseudomonas Candida antimicrobial antifungal.Electric Literature of C10H9BrN2S.
New 2,3-substituted-1,3-thiazolidin-4-one (6a-f) were prepared by cyclocondensation of 2-[6-(4-chlorobenzyloxy)-2-naphthyliden]-4- (4-substituted phenyl)-5-methyl-1,3-thiazole (5a-f) and mercaptoacetic acid in benzene. The synthesized compounds were characterized on the basis of elemental anal., 1H NMR, 13C NMR and FT-IR. The prepared compounds have been screened in vitro against two Gram- pos. Staphylococcus aureus, Staphylococcus epidermidis, and two Gram-neg. Escherichia coli, Pseudomonas aernuginosa for antibacterial activity and two fungal strains Candida albicans, Candida krusei for antifungal activity using ciprofloxacin, ampicillin and ketoconazole with minimal inhibitory concentration (MIC) value of 10 mcg/L in DMSO. Compounds 6a and 6d showed good antibacterial and antifungal activities compared to reference medications utilized within this study.
There is still a lot of research devoted to this compound(SMILES：NC1=NC(C2=CC=C(Br)C=C2)=C(C)S1)Electric Literature of C10H9BrN2S, and with the development of science, more effects of this compound(65705-44-4) can be discovered.
Reference:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics